scholarly journals Responsiveness of Patient‐Reported Outcomes Measurement Information System Measures in Rheumatoid Arthritis Patients Starting or Switching a Disease‐Modifying Antirheumatic Drug

2019 ◽  
Vol 71 (4) ◽  
pp. 521-529 ◽  
Author(s):  
Alyssa Wohlfahrt ◽  
Clifton O. Bingham ◽  
Wendy Marder ◽  
Kristine Phillips ◽  
Marcy B. Bolster ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Information System ◽  
Patient Reported Outcomes ◽  
Antirheumatic Drug ◽  
Measurement Information ◽  
Outcomes Measurement ◽  
Patient Reported ◽  
Measurement Information System ◽  
Disease Modifying ◽  
Disease Modifying Antirheumatic Drug

Meaningful change thresholds for Patient-Reported Outcomes Measurement Information System (PROMIS) fatigue and pain interference scores in patients with rheumatoid arthritis

2021 ◽  
pp. jrheum.200990
Author(s):  
Jennifer L. Beaumont ◽  
Elizabeth S. Davis ◽  
James F. Fries ◽  
Jeffrey R. Curtis ◽  
David Cella ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Information System ◽  
Patient Reported Outcomes ◽  
Pain Interference ◽  
Measurement Information ◽  
Meaningful Change ◽  
Outcomes Measurement ◽  
Small Effect Size ◽  
Patient Reported ◽  
Measurement Information System

Objective We estimated meaningful change thresholds (MCTs) for Patient-Reported Outcomes Measurement Information System (PROMIS®) Fatigue and Pain Interference in rheumatoid arthritis (RA). Methods The responsiveness of several patient-reported outcomes (PROs) was assessed among 521 RA patients in the Arthritis, Rheumatism, and Aging Medical Information Systems (ARAMIS) cohort. PROMIS Fatigue (7 item) and Pain Interference (6 item) short form instruments were administered at baseline, 6 months, and 12 months. Self-reported retrospective changes over the previous 6 months (a lot better/worse, a little better/worse, stayed the same) were obtained at 6 and 12 months follow-up. We estimated MCTs using the mean change in PROMIS scores for patients who rated their change ‘a little better’ or ‘a little worse.’ Results Baseline fatigue and pain interference scores were near normal (median 54 and 56, respectively). At 6 months, 7.9% of patients reported their fatigue was a little better compared to baseline (mean change [SD]: -2.6 [4.8]), 22.8% a little worse (1.7 [5.6]). Pain was a little better for 11.5% of patients (-1.9 [6.1]) and a little worse for 24.2% of patients (0.6 [5.7]). At 12 months, results were similar. Thus, the MCT range was 1-2 points for both Fatigue and Pain Interference. Correlations between change scores and retrospective ratings were low (0.13-0.29), indicating possible underestimate for MCT. Conclusion The group-level MCT for PROMIS Fatigue and Pain Interference is roughly 2-3 points and corresponds to a small effect size, which is consistent with earlier work demonstrating a MCT of 2 points for PROMIS Physical Functioning.

scholarly journals PERFORMANCE OF PROMIS-29 (PATIENT REPORTED OUTCOMES MEASUREMENT INFORMATION SYSTEM-29) IN PATIENTS OF RHEUMATIOD ARTHRITIS

2021 ◽  
Vol 71 (1) ◽  
pp. 172-78
Author(s):  
Naveed Aslam Lashari ◽  
Saira E.A Khan ◽  
Shabnam Batool ◽  
Asadullah Khan ◽  
Zia U Din
Keyword(s):  
Rheumatoid Arthritis ◽  
Information System ◽  
Disease Activity ◽  
Patient Reported Outcomes ◽  
Outcome Measurement ◽  
High Disease Activity ◽  
Measurement Information ◽  
Outcomes Measurement ◽  
Patient Reported ◽  
Measurement Information System

Objective: To determine the performance of patient reported outcome measurement information system inpatients with rheumatoid arthritis in our setup. Study Design: Cross sectional study. Place and Duration of Study: Division of Rheumatology, Fatima memorial hospital, Lahore Pakistan, from May2019 to Jul 2019. Methodology: A total of 191 patients of either gender, aged more than 16 years with sero +ve rheumatoid arthritis were included in the study. Results: Majority of patients 156 (81.67%) were female and male 35 (18.32%) with mean age 38 ± 12.19 years.Diagnosed as rheumatoid arthritis and compliant with csDMARDs. Out of all these, majority were in low diseaseactivity (LDA) 72 (38%), remission 62 (32%), moderate 42 (22%) and high disease activity 16 (8%). Mean T-score of all measures showed variations of scores as disease progresses. For all measures, mild change was noted between low disease activity and moderate disease activity whereas high difference was seen in remission and high disease activity. Highest correlations were seen among similar constructs of physical health, mental health, and social health. Fatigue was strongly correlated with social role and social activity. Conclusion: There was a considerable impact of rheumatoid arthritis on physical, social and mental healthcalculated with patient reported outcomes measurement information system-29 (PROMIS-29).

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