Protein-Release Behavior of Self-Assembled PEG-β-Cyclodextrin/PEG-Cholesterol Hydrogels

2009 ◽  
Vol 19 (18) ◽  
pp. 2992-3001 ◽  
Author(s):  
Frank van de Manakker ◽  
Kevin Braeckmans ◽  
Najim el Morabit ◽  
Stefaan C. De Smedt ◽  
Cornelus F. van Nostrum ◽  
...  
Keyword(s):  
Protein Release ◽  
Release Behavior ◽  
Self Assembled

The effect of self-assembled layers on the release behavior of rifampicin-loaded silicone

2007 ◽  
Vol 18 (6) ◽  
pp. 687-700 ◽  
Author(s):  
Xuemei Liang ◽  
Anfeng Wang ◽  
Haiying Tang ◽  
Ting Cao ◽  
James P. Mcallister ◽  
...  
Keyword(s):  
Release Behavior ◽  
Self Assembled

scholarly journals A Photocleavable Amphiphilic Prodrug Self-Assembled Nanoparticles with Effective Anticancer Activity In Vitro

Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 860 ◽  
Author(s):  
Ji Chen ◽  
Guotao Li ◽  
Qihong Liu ◽  
Yan Liang ◽  
Miaochang Liu ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Laser Irradiation ◽  
Pharmacological Action ◽  
Coumarin Derivative ◽  
Intracellular Uptake ◽  
Release Behavior ◽  
Triggered Drug Release ◽  
Self Assembled ◽  
Clinical Drug

Accelerating degradation of prodrug is an effective strategy for improving the pharmacological action. A photocleavable amphiphilic prodrug of methotrexate-coumarin derivative-PEG conjugates (MTX-AMC-PEG) with photo-triggered breakage to release clinical drug under laser irradiation was fabricated and self-assembled into nanoparticles for chemotherapy. The nanoparticles exhibited good intracellular uptake and excellent photolysis release of MTX, which resulted in efficient anticancer activity in vitro with laser irradiation. This research provides a way to fabricate photocleavable prodrug nanoparticles with stimuli-triggered drug release behavior.

Artificial peptide-controlled protein release of Zn2+-triggered, self-assembled histidine-tagged protein microparticle

2020 ◽  
Vol 187 ◽  
pp. 110644 ◽  
Author(s):  
Tzu-Yin Chen ◽  
Wan-Jung Cheng ◽  
Jia-Cherng Horng ◽  
Hsin-Yun Hsu
Keyword(s):  
Protein Release ◽  
Self Assembled

Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers

2016 ◽  
Vol 4 (18) ◽  
pp. 3054-3064 ◽  
Author(s):  
Margaret M. Fettis ◽  
Yaohua Wei ◽  
Antonietta Restuccia ◽  
Justin J. Kurian ◽  
Shannon M. Wallet ◽  
...  
Keyword(s):  
Protein Binding ◽  
Protein Release ◽  
Peptide Nanofibers ◽  
Self Assembled

We demonstrate an approach to fabricate microgels from self-assembled peptide nanofibers via desolvation. Proteins can be co-desolvated with nanofibers to create protein-loaded microgels. Modifying nanofibers with a protein-binding ligand provides tunable affinity-controlled protein release.

Protein release behavior from carbonate apatite hydrogel

2006 ◽  
Vol 26 (4-5) ◽  
pp. 519-523 ◽  
Author(s):  
Yoshiyuki Yokogawa ◽  
Fukue Nagata ◽  
Katsuya Kato ◽  
Yoshikazu Shiotsu ◽  
Makoto Watanabe
Keyword(s):  
Protein Release ◽  
Carbonate Apatite ◽  
Release Behavior

Polyelectrolyte complex beads composed of water-soluble chitosan/alginate: Characterization and their protein release behavior

2006 ◽  
Vol 100 (6) ◽  
pp. 4614-4622 ◽  
Author(s):  
Xiaowen Shi ◽  
Yumin Du ◽  
Liping Sun ◽  
Baozhong Zhang ◽  
Abo Dou
Keyword(s):  
Polyelectrolyte Complex ◽  
Protein Release ◽  
Water Soluble ◽  
Release Behavior

Protein release behavior from porous microparticle with lysozyme/hyaluronate ionic complex

2007 ◽  
Vol 55 (1) ◽  
pp. 125-130 ◽  
Author(s):  
Eun Seong Lee ◽  
Min Jung Kwon ◽  
Kun Na ◽  
Jun Ho Bae
Keyword(s):  
Protein Release ◽  
Release Behavior ◽  
Ionic Complex
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