Base-Pairing Properties of a Structural Isomer of Glycerol Nucleic Acid

2013 ◽  
Vol 125 (22) ◽  
pp. 5952-5956 ◽  
Author(s):  
Phaneendrasai Karri ◽  
Venkateshwarlu Punna ◽  
Keunsoo Kim ◽  
Ramanarayanan Krishnamurthy
2013 ◽  
Vol 52 (22) ◽  
pp. 5840-5844 ◽  
Author(s):  
Phaneendrasai Karri ◽  
Venkateshwarlu Punna ◽  
Keunsoo Kim ◽  
Ramanarayanan Krishnamurthy

2014 ◽  
Vol 10 ◽  
pp. 2131-2138 ◽  
Author(s):  
Keunsoo Kim ◽  
Venkateshwarlu Punna ◽  
Phaneendrasai Karri ◽  
Ramanarayanan Krishnamurthy

IsoGNA, an isomer of glycerol nucleic acid GNA, is a flexible (acyclic) nucleic acid with bases directly attached to its linear backbone. IsoGNA exhibits (limited) base-pairing properties which are unique compared to other known flexible nucleic acids. Herein, we report on the details of the preparation of isoGNA phosphoramidites and an alternative route for the synthesis of the adenine derivative. The synthetic improvements described here enable an easy access to isoGNA and allows for the further exploration of this structural unit in oligonucleotide chemistry thereby spurring investigations of its usefulness and applicability.


2002 ◽  
Vol 59 (12) ◽  
pp. 792-799
Author(s):  
Takahiro HARADA ◽  
Takashi MIYAHARA ◽  
Naotoshi NAKASHIMA ◽  
Kazue KURIHARA

1991 ◽  
Vol 95 (4) ◽  
pp. 1530-1532 ◽  
Author(s):  
Anthony Harriman ◽  
Darren J. Magda ◽  
Jonathan L. Sessler

1992 ◽  
Vol 20 (19) ◽  
pp. 5011-5016 ◽  
Author(s):  
Richard Lavery ◽  
Krystyna Zakrzewska ◽  
Jian-Sheng Sun ◽  
Stephen C. Harvey

2014 ◽  
Vol 5 (4) ◽  
pp. 1533-1537 ◽  
Author(s):  
Kyoung-Ran Kim ◽  
Taemin Lee ◽  
Byeong-Su Kim ◽  
Dae-Ro Ahn
Keyword(s):  

CrystEngComm ◽  
2017 ◽  
Vol 19 (37) ◽  
pp. 5679-5685 ◽  
Author(s):  
Elizabeth S. Koch ◽  
Kelly A. McKenna ◽  
Hyo Jung Kim ◽  
Victor G. Young ◽  
Jennifer A. Swift

Cocrystal design through DNA-type base pairing between a nucleic acid and complementary heterocycles.


Biopolymers ◽  
1994 ◽  
Vol 34 (12) ◽  
pp. 1573-1581 ◽  
Author(s):  
G. Raghunathan ◽  
H. Todd Miles ◽  
V. Sasisekharan

Sign in / Sign up

Export Citation Format

Share Document