scholarly journals Mouse Hind Limb Skeletal Muscle Functional Adaptation in a Simulated Fine Branch Arboreal Habitat

2018 ◽  
Vol 301 (3) ◽  
pp. 434-440 ◽  
Author(s):  
Joseph E. Rupert ◽  
J. Ethan Joll ◽  
Wiaam Y. Elkhatib ◽  
Jason M. Organ
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Functional Adaptation ◽  
Arboreal Habitat ◽  
Fine Branch

Countercurrent compartmental models describe hind limb skeletal muscle helium kinetics at resting and low blood flows in sheep

2005 ◽  
Vol 185 (2) ◽  
pp. 109-121 ◽  
Author(s):  
D. J. Doolette ◽  
R. N. Upton ◽  
C. Grant
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Compartmental Models ◽  
Blood Flows

scholarly journals The Ubr2 gene is expressed in skeletal muscle atrophying as a result of hind limb suspension, but not Merg1a expression alone

2014 ◽  
Vol 24 (3) ◽  
Author(s):  
Gregory H. Hockerman ◽  
Nicole M. Dethrow ◽  
Sohaib Hameed ◽  
Maureen Doran ◽  
Christine Jaeger ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Hind Limb Suspension

scholarly journals Apolipoprotein E–/– mice have delayed skeletal muscle healing after hind limb ischemia–reperfusion

2008 ◽  
Vol 48 (3) ◽  
pp. 701-708 ◽  
Author(s):  
Jeanwan Kang ◽  
Hassan Albadawi ◽  
Virendra I. Patel ◽  
Thomas A. Abbruzzese ◽  
Jin-Hyung Yoo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Apolipoprotein E ◽  
Hind Limb ◽  
Ischemia Reperfusion ◽  
Limb Ischemia ◽  
Hind Limb Ischemia

scholarly journals Slow- and fast-twitch rat hind limb skeletal muscle phenotypes 8 months after spinal cord transection and olfactory ensheathing glia transplantation

2008 ◽  
Vol 586 (10) ◽  
pp. 2593-2610 ◽  
Author(s):  
Pilar Negredo ◽  
José-Luis L. Rivero ◽  
Beatriz González ◽  
Almudena Ramón-Cueto ◽  
Rafael Manso
Keyword(s):  
Skeletal Muscle ◽  
Spinal Cord ◽  
Hind Limb ◽  
Spinal Cord Transection ◽  
Olfactory Ensheathing Glia ◽  
Fast Twitch

Evaluation of skeletal muscle perfusion in canine hind limb ischemia model using color-coded digital subtraction angiography

2019 ◽  
Vol 123 ◽  
pp. 81-85 ◽  
Author(s):  
Tao Wang ◽  
Haobo Su ◽  
Wensheng Lou ◽  
Jianping Gu ◽  
Xu He ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Digital Subtraction Angiography ◽  
Hind Limb ◽  
Limb Ischemia ◽  
Digital Subtraction ◽  
Muscle Perfusion ◽  
Hind Limb Ischemia

scholarly journals Experimental supporting data on evaluation of skeletal muscle perfusion in canine hind limb ischemia model using color-coded digital subtraction angiography

Data in Brief ◽  
2019 ◽  
Vol 25 ◽  
pp. 103737
Author(s):  
Tao Wang ◽  
Haobo Su ◽  
Wensheng Lou ◽  
Jianping Gu ◽  
Xu He ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Digital Subtraction Angiography ◽  
Hind Limb ◽  
Limb Ischemia ◽  
Digital Subtraction ◽  
Muscle Perfusion ◽  
Hind Limb Ischemia

Effect of respiratory alkalosis on skeletal muscle metabolism in the dog

1985 ◽  
Vol 58 (2) ◽  
pp. 658-664 ◽  
Author(s):  
A. G. Brice ◽  
H. G. Welch
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Gastrocnemius Muscle ◽  
Minute Ventilation ◽  
Lactate Concentration ◽  
Muscle Metabolism ◽  
Respiratory Alkalosis ◽  
Whole Body ◽  
Venous Blood Flow ◽  
Skeletal Muscle Metabolism

These experiments were conducted to determine whether changes in skeletal muscle metabolism contribute to the previously reported increase in whole-body O2 uptake (VO2) during respiratory alkalosis. The hind-limb and gastrocnemius-plantaris preparations in anesthetized and paralyzed dogs were used. VO2 of the hindlimb and gastrocnemius muscle was calculated from measurements of venous blood flow and arterial and venous O2 concentrations (Van Slyke analysis). Whole-body VO2 was measured by the open-circuit method. Minute ventilation (hence blood gases and pH) was controlled by a mechanical respirator. Whole-body, hind-limb, and gastrocnemius muscle VO2 increased 14, 19, and 20%, respectively, during alkalosis (P less than 0.05). In all experiments, arterial lactate concentration increased significantly (P less than 0.05) during alkalosis. A positive venoarterial lactate difference across muscle during alkalosis indicated that skeletal muscle is a source of the elevated blood lactate. We concluded that VO2 of resting skeletal muscle is increased during states of respiratory alkalosis and that this increase can account for much of the increase in whole-body VO2.

scholarly journals Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice

1998 ◽  
Vol 337 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Garret J. ETGEN ◽  
William J. ZAVADOSKI ◽  
Geoffrey D. HOLMAN ◽  
E. Michael GIBBS
Keyword(s):  
Skeletal Muscle ◽  
Cell Surface ◽  
Transgenic Mice ◽  
Glucose Transport ◽  
Hind Limb ◽  
Glucose Transporter ◽  
Glut4 Translocation ◽  
Transport Activity ◽  
Fast Twitch Muscle ◽  
Fast Twitch

Skeletal muscle glucose transport was examined in transgenic mice overexpressing the glucose transporter GLUT1 using both the isolated incubated-muscle preparation and the hind-limb perfusion technique. In the absence of insulin, 2-deoxy-d-glucose uptake was increased ∼ 3–8-fold in isolated fast-twitch muscles of GLUT1 transgenic mice compared with non-transgenic siblings. Similarly, basal glucose transport activity was increased ∼ 4–14-fold in perfused fast-twitch muscles of transgenic mice. In non-transgenic mice insulin accelerated glucose transport activity ∼ 2–3-fold in isolated muscles and to a much greater extent (∼ 7–20-fold) in perfused hind-limb preparations. The observed effect of insulin on glucose transport in transgenic muscle was similarly dependent upon the technique used for measurement, as insulin had no effect on isolated fast-twitch muscle from transgenic mice, but significantly enhanced glucose transport in perfused fast-twitch muscle from transgenic mice to ∼ 50–75% of the magnitude of the increase observed in non-transgenic mice. Cell-surface glucose transporter content was assessed via 2-N-4-(l-azi-2,2,2-trifluoroethyl)benzoyl-1,3-bis-(d -mannos-4-yloxy)-2-propylamine photolabelling methodology in both isolated and perfused extensor digitorum longus (EDL). Cell-surface GLUT1 was enhanced by as much as 70-fold in both isolated and perfused EDL of transgenic mice. Insulin did not alter cell-surface GLUT1 in either transgenic or non-transgenic mice. Basal levels of cell-surface GLUT4, measured in either isolated or perfused EDL, were similar in transgenic and non-transgenic mice. Interestingly, insulin enhanced cell-surface GLUT4 ∼ 2-fold in isolated EDL and ∼ 6-fold in perfused EDL of both transgenic and non-transgenic mice. In summary, these results reveal differences between isolated muscle and perfused hind-limb techniques, with the latter method showing a more robust responsiveness to insulin. Furthermore, the results demonstrate that muscle overexpressing GLUT1 has normal insulin-induced GLUT4 translocation and the ability to augment glucose-transport activity above the elevated basal rates.

Effect of hind-limb immobilization on contractile and histochemical properties of skeletal muscle

1973 ◽  
Vol 342 (3) ◽  
pp. 231-238 ◽  
Author(s):  
F. W. Booth ◽  
J. R. Kelso
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Limb Immobilization

Effect of Neutrophil Depletion on Extracellular Traps Accumulation in Skeletal Muscle tissue Following Hind Limb Ischemia Reperfusion Injury

2014 ◽  
Vol 186 (2) ◽  
pp. 692
Author(s):  
H. Albadawi ◽  
R. Oklu ◽  
R.M. O'Keefe ◽  
N.R. Cormier ◽  
M. Sillesen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Reperfusion Injury ◽  
Muscle Tissue ◽  
Hind Limb ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Limb Ischemia ◽  
Skeletal Muscle Tissue ◽  
Extracellular Traps ◽  
Neutrophil Depletion
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