HLA–B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease

Hla B27 ◽

Transgenic Rats ◽

Heavy Chains ◽

Unfolded Protein ◽

Faculty Opinions recommendation of HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.724437679.793503040 ◽

2015 ◽

Author(s):

William St Clair

Keyword(s):

Hla B27 ◽

Transgenic Rats ◽

Heavy Chains ◽

Unfolded Protein ◽

HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats

Arthritis & Rheumatism ◽

10.1002/art.24763 ◽

2009 ◽

Vol 60 (9) ◽

pp. 2633-2643 ◽

Cited By ~ 244

Author(s):

Monica L. DeLay ◽

Matthew J. Turner ◽

Erin I. Klenk ◽

Judith A. Smith ◽

Dawn P. Sowders ◽

...

Keyword(s):

Hla B27 ◽

Transgenic Rats ◽

Unfolded Protein ◽

Interleukin 23 ◽

HLA-B27 Misfolding in Transgenic Rats Is Associated with Activation of the Unfolded Protein Response

The Journal of Immunology ◽

10.4049/jimmunol.175.4.2438 ◽

2005 ◽

Vol 175 (4) ◽

pp. 2438-2448 ◽

Cited By ~ 175

Author(s):

Matthew J. Turner ◽

Dawn P. Sowders ◽

Monica L. DeLay ◽

Rajashree Mohapatra ◽

Shuzhen Bai ◽

...

Keyword(s):

Hla B27 ◽

Transgenic Rats ◽

Unfolded Protein ◽

OP0279 The Unfolded Protein Response Genes in Synovium and Blood Mononuclear Cells of HLA-B27 Positive Ankylosing Spondylitis Patients is not Increased Compared to Other Arthritis Patients and Healthy Controls

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.484 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A148.2-A148

Author(s):

B. Neerinckx ◽

S. Carter ◽

R. Lories

Keyword(s):

Ankylosing Spondylitis ◽

Mononuclear Cells ◽

Healthy Controls ◽

Hla B27 ◽

Unfolded Protein ◽

Blood Mononuclear Cells ◽

Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes

FEBS Letters ◽

10.1016/j.febslet.2007.03.069 ◽

2007 ◽

Vol 581 (9) ◽

pp. 1819-1824 ◽

Cited By ~ 11

Author(s):

Andrew J. Lemin ◽

Khalil Saleki ◽

Marcel van Lith ◽

Adam M. Benham

Keyword(s):

Alternative Splicing ◽

Hla B27 ◽

Unfolded Protein ◽

IL-23 expression and activation of autophagy in synovium and PBMCs of HLA-B27 positive patients with ankylosing spondylitis. Response to: ‘Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation’ by Cicciaet al

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-206277 ◽

2014 ◽

Vol 73 (11) ◽

pp. e68-e68 ◽

Cited By ~ 13

Author(s):

B Neerinckx ◽

S Carter ◽

R Lories

Keyword(s):

Ankylosing Spondylitis ◽

Hla B27 ◽

Gut Inflammation ◽

Unfolded Protein ◽

Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLA–B27 Activates the Unfolded Protein Response

Arthritis & Rheumatology ◽

10.1002/art.40033 ◽

2017 ◽

Vol 69 (5) ◽

pp. 1009-1015 ◽

Cited By ~ 8

Author(s):

Zhenbo Zhang ◽

Francesco Ciccia ◽

Fanxing Zeng ◽

Giuliana Guggino ◽

Kirby Yee ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Hla B27 ◽

Functional Interaction ◽

Unfolded Protein ◽

Oestrogen-driven changes in the bovine uterus are associated with activation of the unfolded protein response

Reproduction Abstracts ◽

10.1530/repabs.1.p007 ◽

2014 ◽

Author(s):

Mohammed A Alfattah ◽

Paul Anthony McGettigan ◽

John Arthur Browne ◽

Khalid M Alkhodair ◽

Katarzyna Pluta ◽

...

Keyword(s):

Unfolded Protein ◽

Faculty Opinions recommendation of The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007041.165807 ◽

2002 ◽

Author(s):

David Ron

Keyword(s):

Disease Severity ◽

Unfolded Protein ◽

Protein Response ◽

Pelizaeus Merzbacher Disease

Faculty Opinions recommendation of Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013206.189603 ◽

2003 ◽

Author(s):

Dan Conrad

Keyword(s):

Transcription Factor ◽

Cell Differentiation ◽

Plasma Cell ◽

Plasma Cell Differentiation ◽

Unfolded Protein ◽