Evaluation of antityrosinase activity and mechanism, antioxidation, and UV filter properties of theaflavin

2021 ◽  
Author(s):  
Jianmin Chen ◽  
Mengnan Ran ◽  
Meixia Wang ◽  
Xinying Liu ◽  
Siwan Liu ◽  
...  
Keyword(s):  
Uv Filter ◽  
Antityrosinase Activity

LC-MS and NMR guided isolation of monoterpene dimers from cultivated Thymus vulgaris Varico 3 hybrid and their antityrosinase activity

2019 ◽  
Author(s):  
I Stefanis ◽  
D Hadjipavlou-Litina ◽  
AR Bilia ◽  
A Karioti
Keyword(s):  
Thymus Vulgaris ◽  
Antityrosinase Activity

A Study on UV Filter Chemicals from Annex VII of European Union Directive 76/768/EEC, in the In Vitro 3T3 NRU Phototoxicity Test

1998 ◽  
Vol 26 (5) ◽  
pp. 679-708 ◽  
Author(s):  
Horst Spielmann ◽  
Michael Balls ◽  
Jack Dupuis ◽  
Wolfgang J. W. Pape ◽  
Odile de Silva ◽  
...  
Keyword(s):  
Neutral Red ◽  
Optimum Concentration ◽  
Alternative Methods ◽  
Uv Filter ◽  
Eu Directive ◽  
Optimum Concentration Range ◽  
The Impact ◽  
Positive Results

In 1996, the Scientific Committee on Cosmetology of DGXXIV of the European Commission asked the European Centre for the Validation of Alternative Methods to test eight UV filter chemicals from the 1995 edition of Annex VII of Directive 76/768/EEC in a blind trial in the in vitro 3T3 cell neutral red uptake phototoxicity (3T3 NRU PT) test, which had been scientifically validated between 1992 and 1996. Since all the UV filter chemicals on the positive list of EU Directive 76/768/EEC have been shown not to be phototoxic in vivo in humans under use conditions, only negative effects would be expected in the 3T3 NRU PT test. To balance the number of positive and negative chemicals, ten phototoxic and ten non-phototoxic chemicals were tested under blind conditions in four laboratories. Moreover, to assess the optimum concentration range for testing, information was provided on appropriate solvents and on the solubility of the coded chemicals. In this study, the phototoxic potential of test chemicals was evaluated in a prediction model in which either the Photoirritation Factor (PIF) or the Mean Photo Effect (MPE) were determined. The results obtained with both PIF and MPE were highly reproducible in the four laboratories, and the correlation between in vitro and in vivo data was almost perfect. All the phototoxic test chemicals provided a positive result at concentrations of 1μg/ml, while nine of the ten non-phototoxic chemicals gave clear negative results, even at the highest test concentrations. One of the UV filter chemicals gave positive results in three of the four laboratories only at concentrations greater than 100μg/ml; the other laboratory correctly identified all 20 of the test chemicals. An analysis of the impact that exposure concentrations had on the performance of the test revealed that the optimum concentration range in the 3T3 NRU PT test for determining the phototoxic potential of chemicals is between 0.1μg/ml and 10μg/ml, and that false positive results can be obtained at concentrations greater than 100μg/ml. Therefore, the positive results obtained with some of the UV filter chemicals only at concentrations greater than 100μg/ml do not indicate a phototoxic potential in vivo. When this information was taken into account during calculation of the overall predictivity of the 3T3 NRU PT test in the present study, an almost perfect correlation of in vitro versus in vivo results was obtained (between 95% and 100%), when either PIF or MPE were used to predict the phototoxic potential. The management team and participants therefore conclude that the 3T3 NRU PT test is a valid test for correctly assessing the phototoxic potential of UV filter chemicals, if the defined concentration limits are taken into account.

scholarly journals Multifunctional Activities of Gold Nanoparticles Biosynthesized Using Bacteria Isolated from Mining Areas

2021 ◽  
Vol 11 (8) ◽  
pp. 3670
Author(s):  
Chih-Yu Chen ◽  
Yung-Chu Chang ◽  
Teh-Hua Tsai ◽  
Man-Hai Liu ◽  
Ying-Chien Chung
Keyword(s):  
Gold Nanoparticles ◽  
Mining Area ◽  
Synthesis Process ◽  
Average Particle ◽  
Bifidobacterium Lactis ◽  
E Coli ◽  
Mining Areas ◽  
Skin Cells ◽  
Study Results ◽  
Antityrosinase Activity

Research on gold nanoparticles (AuNPs) has often focused on their physical, chemical, and crystalline characteristics. Commercial AuNPs have been applied in the diverse fields of biomedicine, catalysis, photovoltaics, and sensing. In this study, we explored the various activities of AuNPs to widen their applicability. This paper presents a simple and rapid synthesis process of AuNPs with bacteria isolated from a gold mining area. We also investigated the optimization of reaction parameters for AuNP synthesis. The study results revealed that among the isolated strains, Bifidobacterium lactis and Escherichia coli demonstrated the highest capabilities of AuNP synthesis. The optimal pH values for AuNP synthesis by B. lactis (BLAuNPs) and E. coli (ECAuNPs) were 5.0 for 72 h of incubation and 8.0 for 24 h of incubation. The average particle sizes of ECAuNPs and BLAuNPs were 4.2 and 5.6 nm, respectively. Furthermore, these biogenic AuNPs were found to be stable with no aggregation after 3 months of storage. BLAuNPs and ECAuNPs exhibited high levels of antimicrobial, antioxidant, photocatalytic, and antityrosinase activity. Moreover, they were noncytotoxic to skin cells even at 100% melanin inhibitory concentrations. Considering the demonstrated multifunctional activities of AuNPs, BLAuNPs and ECAuNPs have promising potential for commercialization.

Design, synthesis and biological evaluation of hydroxy substituted amino chalcone compounds for antityrosinase activity in B16 cells

2015 ◽  
Vol 62 ◽  
pp. 117-123 ◽  
Author(s):  
Sini Radhakrishnan ◽  
Ronald Shimmon ◽  
Costa Conn ◽  
Anthony Baker
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Antityrosinase Activity ◽  
Synthesis And Biological Evaluation

Identification of a new human lens UV filter compound

FEBS Letters ◽  
2001 ◽  
Vol 509 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Lisa M. Taylor ◽  
J.Andrew Aquilina ◽  
Richard H. Willis ◽  
Joanne F. Jamie ◽  
Roger J.W. Truscott
Keyword(s):  
Human Lens ◽  
Uv Filter

scholarly journals Commonly used UV filter toxicity on biological functions: review of last decade studies

2013 ◽  
Vol 35 (3) ◽  
pp. 208-219 ◽  
Author(s):  
E. Gilbert ◽  
F. Pirot ◽  
V. Bertholle ◽  
L. Roussel ◽  
F. Falson ◽  
...  
Keyword(s):  
Biological Functions ◽  
Uv Filter

Ultraviolet reflectance and female mating preferences in the common kestrel (Falco tinnunculus)

2008 ◽  
Vol 86 (6) ◽  
pp. 479-483 ◽  
Author(s):  
E. Zampiga ◽  
G. Gaibani ◽  
D. Csermely
Keyword(s):  
Female Mate Choice ◽  
Female Preference ◽  
Visible Spectral Range ◽  
Falco Tinnunculus ◽  
Uv Filter ◽  
Skin Reflectance ◽  
Ultraviolet Reflectance ◽  
Uv Reflectance ◽  
Female Mating Preferences ◽  
Uv Reflection

Previous studies revealed the importance of plumage brightness (considering only the visible spectral range) in female mate choice of common kestrels ( Falco tinnunculus L., 1758). Our study focuses on the effect of UV reflectance on female preference; we hypothesize that common kestrel females prefer males with UV-reflecting plumage and refuse, or are not attracted to, males whose plumage UV reflectance is prevented. We tested the preference of 20 captive females who were given a choice between two males, one behind a UV-transmitting (UV+) filter and another one behind a UV-blocking (UV–) filter. Female preference was measured as frequency and duration of visits to either male, specifically by sitting on the perch or hanging on to the partition wall. Females visited the male behind the UV+ filter more often than the male behind the UV– filter, indicating that females prefer males with UV-reflecting plumage than males without UV reflection. UV plumage and skin reflectance could provide females with information regarding current male conditions more so than other colours and other morphological parameters.

Improved uv Filter for Isolation of the 2537‐A Line of a Mercury Low‐Pressure Lamp

1958 ◽  
Vol 29 (8) ◽  
pp. 738-739 ◽  
Author(s):  
Robert H. McFarland ◽  
Richard A. Anderson ◽  
Mohammed Nasim ◽  
Donald G. McDonald
Keyword(s):  
Low Pressure ◽  
Uv Filter

A new UV-filter compound in human lenses

FEBS Letters ◽  
1994 ◽  
Vol 348 (2) ◽  
pp. 173-176 ◽  
Author(s):  
Roger J.W. Truscott ◽  
Andrew M. Wood ◽  
John A. Carver ◽  
Margaret M. Sheil ◽  
Glen M. Stutchbury ◽  
...  
Keyword(s):  
Uv Filter ◽  
Human Lenses
Sign in / Sign up

Export Citation Format

Share Document