Effects of Maternal Exposure to Piperonyl Butoxide (PBO) on Behavioral Development in F1-Generation Mice

2015 ◽  
Vol 104 (6) ◽  
pp. 227-237 ◽  
Author(s):  
Toyohito Tanaka ◽  
Akiko Inomata
Keyword(s):  
Behavioral Development ◽  
Maternal Exposure ◽  
Piperonyl Butoxide ◽  
F1 Generation

Effects of piperonyl butoxide on spontaneous behavior in F1-generation mice

2009 ◽  
Vol 25 (7) ◽  
pp. 489-497 ◽  
Author(s):  
Toyohito Tanaka ◽  
Osamu Takahashi ◽  
Shinshi Oishi ◽  
Akio Ogata
Keyword(s):  
Dose Group ◽  
Female Offspring ◽  
Piperonyl Butoxide ◽  
High Dose Group ◽  
High Dose ◽  
Adult Females ◽  
Developmental Parameters ◽  
Spontaneous Behavior ◽  
Dose Levels ◽  
F1 Generation

Piperonyl butoxide was given in the diet to provide levels of 0 (control), 0.02%, 0.06%, and 0.18% from 5 weeks of age of the F0 generation to 12 weeks of age of the F1 generation in mice. Select reproductive and neurobehavioral parameters were then measured. In exploratory behavior in the F0 generation, vertical time of adult females increased significantly in a dose-related manner. In behavioral developmental parameters, cliff avoidance was delayed significantly in the high-dose group in male offspring, and this effect was significantly dose-related. In female offspring, surface righting was significantly delayed in the high-dose group, and this effect was significantly dose-related. In spontaneous behavior in the F1 generation, females showed more activities in some variables in the high-dose group. Dose levels of piperonyl butoxide used in the present study produced several adverse effects in neurobehavioral parameters in mice.

Combined effects of maternal exposure to fungicides on behavioral development in F 1 ‐generation mice: 2. Fixed‐dose study of thiabendazole

2020 ◽  
Vol 112 (20) ◽  
pp. 1809-1824
Author(s):  
Toyohito Tanaka ◽  
Toshinari Suzuki ◽  
Akiko Inomata ◽  
Takako Moriyasu
Keyword(s):  
Behavioral Development ◽  
Maternal Exposure ◽  
Fixed Dose ◽  
Combined Effects ◽  
Dose Study

scholarly journals Effects of maternal exposure to thiamazole on behavioral development in infant cynomolgus monkeys

2013 ◽  
Vol 53 (4) ◽  
pp. 149-154
Author(s):  
Ayumi Inoue ◽  
Akihiro Arima ◽  
Hirohito Kato ◽  
Nobuyoshi Yamashita ◽  
Yoshiro Nishida ◽  
...  
Keyword(s):  
Behavioral Development ◽  
Maternal Exposure ◽  
Cynomolgus Monkeys

scholarly journals Toxicogenomic study in rat thymus of F1 generation offspring following maternal exposure to silver ion

2015 ◽  
Vol 2 ◽  
pp. 341-350 ◽  
Author(s):  
Xiugong Gao ◽  
Jeffrey J. Yourick ◽  
Vanessa D. Topping ◽  
Thomas Black ◽  
Nicholas Olejnik ◽  
...  
Keyword(s):  
Maternal Exposure ◽  
Silver Ion ◽  
F1 Generation ◽  
Generation Offspring

scholarly journals Cadmium Enhances Locomotor Behaviour in F1 Generation Mice Following Maternal Exposure During Lactation: Modulation by Quercetin

2017 ◽  
Vol 03 (01) ◽  
Author(s):  
Sumita Halder ◽  
Rajarshi Kar ◽  
Nilesh Chandra ◽  
Swapan K Bhattacharya ◽  
Pramod K Mediratta ◽  
...  
Keyword(s):  
Maternal Exposure ◽  
Locomotor Behaviour ◽  
F1 Generation
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