scholarly journals Randomized clinical trial of 24 versus 72 h antimicrobial prophylaxis in patients undergoing open total gastrectomy for gastric cancer

2017 ◽  
Vol 104 (2) ◽  
pp. e158-e164 ◽  
Author(s):  
A. Takagane ◽  
Y. Mohri ◽  
T. Konishi ◽  
R. Fukushima ◽  
T. Noie ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Total Gastrectomy ◽  
Antimicrobial Prophylaxis ◽  
Open Total Gastrectomy

Randomized clinical trial of single-versus multiple-dose antimicrobial prophylaxis in gastric cancer surgery

2007 ◽  
Vol 94 (6) ◽  
pp. 683-688 ◽  
Author(s):  
Y. Mohri ◽  
H. Tonouchi ◽  
M. Kobayashi ◽  
K. Nakai ◽  
M Kusunoki ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Multiple Dose ◽  
Antimicrobial Prophylaxis ◽  
Cancer Surgery ◽  
Gastric Cancer Surgery ◽  
Single Versus

Laparoscopic versus open total gastrectomy for clinical stage I gastric cancer: Morbidity and mortality results from a prospective randomized multicenter controlled trial (CLASS02).

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 378-378
Author(s):  
Fenglin Liu ◽  
Changming Huang ◽  
Zekuan Xu ◽  
Xiangqian Su ◽  
Gang Zhao ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Trial ◽  
Postoperative Complication ◽  
Total Gastrectomy ◽  
Intraoperative Complications ◽  
Clinical Stage ◽  
Stage I ◽  
Morbidity And Mortality ◽  
Significant Difference ◽  
Open Total Gastrectomy

378 Background: The safety of laparoscopic total gastrectomy (LTG) for the treatment of gastric cancer remains lack of clinical evidence. The aim of this study was to compare the safety of LTG for clinical stage I gastric cancer with the conventional open total gastrectomy (OTG). Methods: From January 2017 to September 2018, a total of 227 patients with clinical stage T1N0-1M0/T2N0M0 gastric cancer were enrolled in this clinical trial and randomly assigned to Laparoscopic Gastrectomy group (LG, n=113) or Open Gastrectomy group (OG, n=114). The morbidity and mortality within 30 days following surgery, the recovery course, and the postoperative hospital stay between LG group (n=105) and OG group (n=109) were compared. Clavien-Dindo classification system was used to stratify surgical complications. Results: The overall morbidity rate was not significantly different in each group (LG group: 19.05%; OG group: 20.18%; Rate difference [RD]: -1.14%, 95%CI, -11.75%-9.58%). Intraoperative complications occurred in 3 (2.86%) patients in LG group and 4 (3.67%) patients in OG group (RD: -0.81%, 95%CI, -6.52%-4.85%). In addition, there was no significant difference in the overall postoperative complication rate of 18.10% in LG group and 17.43% in OG group (RD: 0.66%, 95%CI, -9.61%-11.01%). Each subtypes of postoperative complication were not significantly different between groups. One patient in LG group died of intra-abdominal bleeding from splenic artery, and there was no significant difference in mortality between LG group and OG group (RD: 0.95%, 95%CI, -2.54%-5.20%). The distribution of severity was similar between the two groups. Conclusions: Experienced surgeons can safely perform LTG with lymphadenectomy for clinical stage I gastric cancer. Clinical trial information: NCT03007550.

Randomized clinical trial comparing standard diet with perioperative oral immunonutrition in total gastrectomy for gastric cancer

2017 ◽  
Vol 104 (4) ◽  
pp. 377-383 ◽  
Author(s):  
S. Ida ◽  
N. Hiki ◽  
H. Cho ◽  
K. Sakamaki ◽  
S. Ito ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Total Gastrectomy ◽  
Standard Diet

scholarly journals A Re-Analysis of a Randomized Clinical Trial for Gastric Cancer Using Interval Censoring

1997 ◽  
Vol 27 (6) ◽  
pp. 445-446 ◽  
Author(s):  
J. Sakamoto ◽  
S. Teramukai ◽  
H. Nakazato ◽  
Y. Ohashi
Keyword(s):  
Gastric Cancer ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Interval Censoring

scholarly journals Dual-center randomized clinical trial exploring the optimal duration of antimicrobial prophylaxis in patients undergoing pancreaticoduodenectomy following biliary drainage

2018 ◽  
Vol 2 (6) ◽  
pp. 442-450 ◽  
Author(s):  
Tomohisa Yamamoto ◽  
Sohei Satoi ◽  
Tsutomu Fujii ◽  
Suguru Yamada ◽  
Hiroaki Yanagimoto ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Biliary Drainage ◽  
Antimicrobial Prophylaxis ◽  
Optimal Duration
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