Surgical management of locally recurrent rectal cancer

1996 ◽  
Vol 83 (3) ◽  
pp. 293-304 ◽  
Author(s):  
P. M. Sagar ◽  
J. H. Pemberton
2017 ◽  
Vol 23 (23) ◽  
pp. 4170 ◽  
Author(s):  
Daniel Jin-Keat Lee ◽  
Peter M Sagar ◽  
Gaitri Sadadcharam ◽  
Kok-Yang Tan

2010 ◽  
Vol 53 (9) ◽  
pp. 1248-1257 ◽  
Author(s):  
Alexander H. Mirnezami ◽  
Peter M. Sagar ◽  
Dara Kavanagh ◽  
Paul Witherspoon ◽  
Peter Lee ◽  
...  

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 3712-3712
Author(s):  
M. Yasui ◽  
M. Ikeda ◽  
Y. Fujie ◽  
T. Shingai ◽  
T. Hata ◽  
...  

Author(s):  
Rosa M. Jimenez-Rodriguez ◽  
Jonathan B. Yuval ◽  
Charles-Etienne Gabriel Sauve ◽  
Isaac Wasserman ◽  
Piyush Aggarwal ◽  
...  

BMC Cancer ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Falk Roeder ◽  
Joerg-Michael Goetz ◽  
Gregor Habl ◽  
Marc Bischof ◽  
Robert Krempien ◽  
...  

2015 ◽  
Vol 41 (3) ◽  
pp. 413-420 ◽  
Author(s):  
K. Uehara ◽  
Z. Ito ◽  
Y. Yoshino ◽  
A. Arimoto ◽  
T. Kato ◽  
...  

2021 ◽  
Author(s):  
JUNICHI SAKAMOTO ◽  
Heita Ozawa ◽  
Hiroki Nakanishi ◽  
Shin Fujita

Introduction: Given that doubling time is an indicator of tumor growth, we assessed the usefulness of carcinoembryonic antigen doubling time (CEA-DT) in prognosis prediction after curative resection for locally recurrent rectal cancer. Methods: During January 1986 to December 2016, 33 patients with locally recurrent rectal cancer who underwent curative resection at our hospital were retrospectively reviewed. The primary endpoint was the 3-year recurrence-free survival (RFS) rate. The Kaplan-Meier method was used to compare RFS rates and evaluate univariate and multivariate analyses for factors associated with oncologic outcomes, including CEA-DT. CEA-DT was classified into two groups: the short and long CEA-DT groups. Results: The 3-year overall survival and RFS rates were 62.6% and 42.4%, respectively. In multivariate analyses, CEA-DT was an independent risk factor for poor RFS. The 3-year RFS rate was significantly better in the long CEA-DT group than in the short CEA-DT group (58.8% vs. 25.0%, p = 0.0063). Conclusion: CEA-DT is a useful prognostic factor that can be assessed before surgery for locally recurrent rectal cancer. Long CEA-DT may indicate a favorable prognosis. Contrarily, short CEA-DT is associated with poor prognosis; therefore, further treatment intervention is necessary for patients with short CEA-DT.


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