Clinical Algorithms for the Surgical Management of Locally Recurrent Rectal Cancer

2010 ◽  
Vol 53 (9) ◽  
pp. 1248-1257 ◽  
Author(s):  
Alexander H. Mirnezami ◽  
Peter M. Sagar ◽  
Dara Kavanagh ◽  
Paul Witherspoon ◽  
Peter Lee ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Surgical Management ◽  
Recurrent Rectal Cancer ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent ◽  
Clinical Algorithms

scholarly journals Advances in surgical management for locally recurrent rectal cancer: How far have we come?

2017 ◽  
Vol 23 (23) ◽  
pp. 4170 ◽  
Author(s):  
Daniel Jin-Keat Lee ◽  
Peter M Sagar ◽  
Gaitri Sadadcharam ◽  
Kok-Yang Tan
Keyword(s):  
Rectal Cancer ◽  
Surgical Management ◽  
Recurrent Rectal Cancer ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent

scholarly journals Surgical Management of Locally Recurrent Rectal Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Niamh M. Hogan ◽  
Myles R. Joyce
Keyword(s):  
Rectal Cancer ◽  
Surgical Technique ◽  
Multidisciplinary Approach ◽  
Recurrent Rectal Cancer ◽  
Recurrence Rates ◽  
New Techniques ◽  
Locally Recurrent Rectal Cancer ◽  
Operative Planning ◽  
Locally Recurrent ◽  
Clinical Algorithms

Developments in chemotherapeutic strategies and surgical technique have led to improved loco regional control of rectal cancer and a decrease in recurrence rates over time. However, locally recurrent rectal cancer continues to present considerable technical challenges and results in significant morbidity and mortality. Surgery remains the only therapy with curative potential. Despite a hostile intra-operative environment, with meticulous pre-operative planning and judicious patient selection, safe surgery is feasible. The potential benefit of new techniques such as intra-operative radiotherapy and high intensity focussed ultrasonography has yet to be thoroughly investigated. The future lies in identification of predictors of recurrence, development of schematic clinical algorithms to allow standardised surgical technique and further research into genotyping platforms to allow individualisation of therapy. This review highlights important aspects of pre-operative planning, intra-operative tips and future strategies, focussing on a multimodal multidisciplinary approach.

The role of surgical management of locally recurrent rectal cancer(LRRC)

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 3712-3712
Author(s):  
M. Yasui ◽  
M. Ikeda ◽  
Y. Fujie ◽  
T. Shingai ◽  
T. Hata ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Surgical Management ◽  
Recurrent Rectal Cancer ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent

Type of recurrence is associated with disease-free survival after salvage surgery for locally recurrent rectal cancer

2021 ◽  
Author(s):  
Rosa M. Jimenez-Rodriguez ◽  
Jonathan B. Yuval ◽  
Charles-Etienne Gabriel Sauve ◽  
Isaac Wasserman ◽  
Piyush Aggarwal ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Salvage Surgery ◽  
Disease Free Survival ◽  
Recurrent Rectal Cancer ◽  
Free Survival ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent ◽  
Disease Free

scholarly journals Intraoperative Electron Radiation Therapy (IOERT) in the management of locally recurrent rectal cancer

BMC Cancer ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Falk Roeder ◽  
Joerg-Michael Goetz ◽  
Gregor Habl ◽  
Marc Bischof ◽  
Robert Krempien ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Radiation Therapy ◽  
Recurrent Rectal Cancer ◽  
Electron Radiation ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent

Aggressive surgical treatment with bony pelvic resection for locally recurrent rectal cancer

2015 ◽  
Vol 41 (3) ◽  
pp. 413-420 ◽  
Author(s):  
K. Uehara ◽  
Z. Ito ◽  
Y. Yoshino ◽  
A. Arimoto ◽  
T. Kato ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Surgical Treatment ◽  
Recurrent Rectal Cancer ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent ◽  
Pelvic Resection

Usefulness of carcinoembryonic antigen doubling time in prognosis prediction after curative resection of locally recurrent rectal cancer: A retrospective study

2021 ◽  
Author(s):  
JUNICHI SAKAMOTO ◽  
Heita Ozawa ◽  
Hiroki Nakanishi ◽  
Shin Fujita
Keyword(s):  
Rectal Cancer ◽  
Carcinoembryonic Antigen ◽  
Curative Resection ◽  
Doubling Time ◽  
Multivariate Analyses ◽  
Recurrent Rectal Cancer ◽  
Oncologic Outcomes ◽  
Prognosis Prediction ◽  
Locally Recurrent Rectal Cancer ◽  
Locally Recurrent

Introduction: Given that doubling time is an indicator of tumor growth, we assessed the usefulness of carcinoembryonic antigen doubling time (CEA-DT) in prognosis prediction after curative resection for locally recurrent rectal cancer. Methods: During January 1986 to December 2016, 33 patients with locally recurrent rectal cancer who underwent curative resection at our hospital were retrospectively reviewed. The primary endpoint was the 3-year recurrence-free survival (RFS) rate. The Kaplan-Meier method was used to compare RFS rates and evaluate univariate and multivariate analyses for factors associated with oncologic outcomes, including CEA-DT. CEA-DT was classified into two groups: the short and long CEA-DT groups. Results: The 3-year overall survival and RFS rates were 62.6% and 42.4%, respectively. In multivariate analyses, CEA-DT was an independent risk factor for poor RFS. The 3-year RFS rate was significantly better in the long CEA-DT group than in the short CEA-DT group (58.8% vs. 25.0%, p = 0.0063). Conclusion: CEA-DT is a useful prognostic factor that can be assessed before surgery for locally recurrent rectal cancer. Long CEA-DT may indicate a favorable prognosis. Contrarily, short CEA-DT is associated with poor prognosis; therefore, further treatment intervention is necessary for patients with short CEA-DT.

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