scholarly journals Late gestational exposure to dexamethasone and fetal programming of abnormal behavior in Wistar Kyoto rats

2021 ◽  
Vol 11 (4) ◽  
Author(s):  
Christine Lalonde ◽  
Julie Grandbois ◽  
Sandhya Khurana ◽  
Alyssa Murray ◽  
Sujeenthar Tharmalingam ◽  
...  
Keyword(s):  
Fetal Programming ◽  
Abnormal Behavior ◽  
Wistar Kyoto Rats ◽  
Gestational Exposure ◽  
Wistar Kyoto

scholarly journals Circulating and local visfatin/Nampt/PBEF levels in spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats

2010 ◽  
Vol 60 (5) ◽  
pp. 317-324 ◽  
Author(s):  
Pei Wang ◽  
Hui Du ◽  
Ruo-Yu Zhang ◽  
Yun-Feng Guan ◽  
Tian-Ying Xu ◽  
...  
Keyword(s):  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto rats

1978 ◽  
Vol 51 (4) ◽  
pp. 429-439 ◽  
Author(s):  
Judith C. Juskevich ◽  
Donald S. Robinson ◽  
David Whitehorn
Keyword(s):  
Hypothalamic Stimulation ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

91 Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats

1993 ◽  
Vol 11 (5) ◽  
pp. S437
Author(s):  
Karl F. Hilgers ◽  
R. Veelken ◽  
H. Geiger ◽  
Detlev Ganten ◽  
F. C. Luft ◽  
...  
Keyword(s):  
Angiotensin I ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

Effects of electroconvulsive seizures on depression-related behavior, memory and neurochemical changes in Wistar and Wistar–Kyoto rats

2014 ◽  
Vol 54 ◽  
pp. 170-178 ◽  
Author(s):  
C. Kyeremanteng ◽  
J.C. MacKay ◽  
J.S. James ◽  
P. Kent ◽  
C. Cayer ◽  
...  
Keyword(s):  
Wistar Kyoto Rats ◽  
Neurochemical Changes ◽  
Wistar Kyoto ◽  
Electroconvulsive Seizures

Increased Pressor Responsiveness to Enkephalin in Spontaneously Hypertensive Rats: The Role of Vasopressin

1980 ◽  
Vol 59 (s6) ◽  
pp. 235s-237s ◽  
Author(s):  
R. W. Rockhold ◽  
J. T. Crofton ◽  
L. Share
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pressor Response ◽  
Cardiovascular Effects ◽  
Hypertensive Rats ◽  
Methionine Enkephalin ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

1. The cardiovascular effects of an enkephalin analogue were examined in spontaneously hypertensive and normotensive Wistar-Kyoto rats. (D-Ala2)-methionine enkephalin caused a biphasic increase in blood pressure and an increase in heart rate after intracerebroventricular injection. 2. The initial pressor response to (D-Ala2)-methionine enkephalin was greater in hypertensive than in normotensive rats. No difference was noted between groups during the secondary pressor response. Heart rate increases paralleled the secondary increase in blood pressure. 3. Naloxone pretreatment abolished the secondary increase in blood pressure and the tachycardia, but did not blunt the initial pressor response in female Wistar-Kyoto rats. 4. Plasma levels of arginine vasopressin were depressed during the plateau phase of the pressor response in hypertensive rats given intracerebroventricular (d-Ala2)-methionine enkephalin. 5. The results suggest that the cardiovascular effects of central enkephalin are not due to vasopressin, but may involve activation of the sympathetic nervous system.

Genetic Relationship Between a Lymphocyte Membrane Abnormality and Blood Pressure in Spontaneously Hypertensive Stroke Prone and Wistar-Kyoto Rats

1987 ◽  
Vol 5 (3) ◽  
pp. 293-297 ◽  
Author(s):  
Philip B. Furspan ◽  
Pentti T. Jokelainen ◽  
Charles F. Sing ◽  
David F. Bohr
Keyword(s):  
Blood Pressure ◽  
Genetic Relationship ◽  
Spontaneously Hypertensive ◽  
Lymphocyte Membrane ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto

Contribution of Vascular Nitric Oxide to Basal Blood Pressure in Conscious Spontaneously Hypertensive Rats and Normotensive Wistar Kyoto Rats

1995 ◽  
Vol 89 (2) ◽  
pp. 177-182 ◽  
Author(s):  
Naoyoshi Minami ◽  
Yutaka Imai ◽  
Jun-Ichiro Hashimoto ◽  
Keishi Abe
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Methyl Ester ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Basal Blood Pressure ◽  
Wistar Kyoto

1. The aim of this study was to clarify the extent to which vascular nitric oxide contributes to basal blood pressure in conscious spontaneously hypertensive rats and normotensive Wistar Kyoto rats. 2. The contribution of vascular nitric oxide to maintenance of blood pressure was estimated by measuring the pressor response to an intravenous injection of nitric oxide synthase inhibitor, Nω-l-arginine methyl ester, given after serial injections of captopril, vasopressin V1-receptor antagonist (V1-antagonist) and ganglion blocker (pentolinium) in conscious spontaneously hypertensive and Wistar Kyoto rats aged 20–28 weeks. To estimate the ‘amplifier property’ of hypertrophied vasculature in spontaneously hypertensive rats, which is known to modulate pressor responses, the lower blood pressure plateau after serial injections of captopril, V1-antagonist and pentolinium and the maximum blood pressure elicited by subsequent injection of increasing doses of phenylephrine were also measured. 3. The serial injections of captopril, V1-antagonist and pentolinium decreased mean arterial pressure from 164 ± 9 mmHg to 67 ± 2 mmHg and from 117 ± 2 mmHg to 49 ± 1 mmHg in spontaneously hypertensive and Wistar Kyoto rats respectively. The subsequent injection of Nω-l-arginine methyl ester restored mean arterial pressure almost to its control levels in both spontaneously hypertensive and Wistar Kyoto rats. The absolute changes in mean arterial pressure elicited by Nω-l-arginine methyl ester were significantly greater in spontaneously hypertensive than in Wistar Kyoto rats (P < 0.01), but there was no significant difference in the responses to Nω-l-arginine methyl ester when they were expressed as percentages of either the lower blood pressure plateau or maximum blood pressure. 4. These results indicate that basal blood pressure in both spontaneous hypertensive and Wistar Kyoto rats is maintained by a balance between vascular nitric oxide and major pressor systems. They also suggest that the vasodilatory effect of vascular nitric oxide does not differ between spontaneously hypertensive and Wistar Kyoto rats, and that the increased pressor effect of Nω-l-arginine methyl ester in spontaneously hypertensive rats is due to a vascular amplifier mechanism.

Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats

1996 ◽  
Vol 14 (2) ◽  
pp. 183-189 ◽  
Author(s):  
Kohtaro Numaguchi ◽  
Kensuke Egashira ◽  
Makoto Sakata ◽  
Hiroaki Shimokawa ◽  
Akira Takeshita
Keyword(s):  
Potassium Channels ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto Rats ◽  
Wistar Kyoto
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