Antimicrobial Peptides and Their Superior Fluorinated Analogues: Structure-Activity Relationships as Revealed by NMR Spectroscopy and MD Calculations

ChemBioChem ◽  
2010 ◽  
Vol 11 (17) ◽  
pp. 2424-2432 ◽  
Author(s):  
M. Dolores Díaz ◽  
Martina Palomino-Schätzlein ◽  
Francisco Corzana ◽  
Cecilia Andreu ◽  
Rodrigo J. Carbajo ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Antimicrobial Peptides ◽  
Structure Activity Relationships ◽  
Structure Activity

Sila-Pharmaka, 26. Mitt. [1]. Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, III / Sila-Pharmaca, 26th Communication [1]. Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, III

1982 ◽  
Vol 37 (11) ◽  
pp. 1461-1471 ◽  
Author(s):  
Reinhold Tacke ◽  
Haryanto Linoh ◽  
Moayad T. Attar-Bashi ◽  
William S. Sheldrick ◽  
Ludger Ernst ◽  
...  
Keyword(s):  
Solid State ◽  
Nmr Spectroscopy ◽  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Agents ◽  
X Ray Diffraction ◽  
Silicon Compounds ◽  
X Ray ◽  
Structure Activity Relationships ◽  
H Nmr ◽  
Structure Activity

The potentially curare-like silicon compounds 8a-8f wore synthesized and investigated with respect to their structure-activity relationships. The conformations of the com­pounds in the solid state and in solution were studied by X-ray diffraction analysis (8a-8e) and 1H NMR spectroscopy (8a-8f), respectively. The muscle relaxing properties of 8a-8f were investigated on the mouse. The observed structure-activity relationships are not in accordance with the classical “14 Å model” for neuromuscular blocking agents.

Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy

FEBS Letters ◽  
2004 ◽  
Vol 577 (3) ◽  
pp. 415-421 ◽  
Author(s):  
Aviva Lapidot ◽  
Veerappan Vijayabaskar ◽  
Alexander Litovchick ◽  
Jingua Yu ◽  
Thomas L. James
Keyword(s):  
Nmr Spectroscopy ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Hiv 1

Application of ‘HESH’ Descriptors for the Structure-Activity Relationships of Antimicrobial Peptides

2009 ◽  
Vol 16 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Mao Shu ◽  
Yongjun Jiang ◽  
Li Yang ◽  
Yuqian Wu ◽  
Hu Mei ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Exploring Structure-Activity Relationships in Synthetic Antimicrobial Peptides (synAMPs) by a Ferrocene Scan

2016 ◽  
Vol 2017 (2) ◽  
pp. 360-367 ◽  
Author(s):  
Jack C. Slootweg ◽  
Pascal Prochnow ◽  
Sandra Bobersky ◽  
Julia E. Bandow ◽  
Nils Metzler-Nolte
Keyword(s):  
Antimicrobial Peptides ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Synthetic Antimicrobial Peptides

Structure-activity relationships and action mechanisms of collagen-like antimicrobial peptides

Biopolymers ◽  
2017 ◽  
Vol 108 (1) ◽  
pp. e22931 ◽  
Author(s):  
Ryo Masuda ◽  
Yui Dazai ◽  
Takehiko Mima ◽  
Takaki Koide
Keyword(s):  
Antimicrobial Peptides ◽  
Structure Activity Relationships ◽  
Action Mechanisms ◽  
Structure Activity
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