Is there randomized controlled trial evidence for the use of nonoxynol-9 to prevent vaginal acquisition of sexually transmitted infections by women from men?

2015 ◽  
Author(s):  
Dane Gruenebaum
Keyword(s):  
Randomized Controlled Trial ◽  
Sexually Transmitted Infections ◽  
Controlled Trial ◽  
Sexually Transmitted ◽  
Randomized Controlled ◽  
Trial Evidence

scholarly journals A randomized controlled trial evaluating combination detection of HIV in Malawian sexually transmitted infections clinics

2021 ◽  
Vol 24 (4) ◽  
Author(s):  
Jane S Chen ◽  
Mitch Matoga ◽  
Brian W Pence ◽  
Kimberly A Powers ◽  
Courtney N Maierhofer ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Sexually Transmitted Infections ◽  
Controlled Trial ◽  
Sexually Transmitted ◽  
Randomized Controlled

scholarly journals Positive deviance for dual-method promotion among women in Uganda: Study protocol for a cluster randomized controlled trial

2020 ◽  
Author(s):  
Hodaka Kosugi ◽  
Akira Shibanuma ◽  
Junko Kiriya ◽  
Ken Ing Cherng Ong ◽  
Stephen Mucunguzi ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Sexually Transmitted Infections ◽  
Controlled Trial ◽  
Positive Deviance ◽  
Cluster Randomized Controlled Trial ◽  
Dual Method ◽  
Sexually Transmitted ◽  
Randomized Controlled ◽  
Unintended Pregnancies ◽  
Cluster Randomized

Abstract Background Dual-method use is known as the most reliable protection against unintended pregnancies and sexually transmitted infections, including HIV. However, it is not commonly used in sub-Sharan Africa, especially among women using highly effective contraceptives. This article describes a protocol to evaluate the effect of an intervention formulated under the positive deviance approach for promoting dual-method use in Uganda. Methods One hundred women will be interviewed using a structured questionnaire to find those practicing dual-method use. Then, in-depth interviews will be conducted with all women using dual-method and ten women using only highly effective contraceptives to identify their unique practice. Then, a cluster randomized controlled trial will be conducted to examine the effect of an intervention formulated under the positive deviance approach on dual-method uptake and adherence. Twenty health facilities will be randomized to an intervention or control arm, and 480 women will be enrolled in each group. The participants will be followed up for eight months. Discussion This trial focuses on women who already adapted dual-method use and identifies their unique solutions to promote dual-method use. This trial could tackle barriers for dual-method use, which expert outsiders may fail to recognize, by analyzing and promulgating their unique behaviors. This study could provide evidence that the positive deviance approach can address unintended pregnancies and sexually transmitted infections as well as other health problems which usual approaches have failed to address.

Video-based education versus nurse-led education for partner notification in Thai women with sexually transmitted infections: a randomized controlled trial

2018 ◽  
Vol 29 (11) ◽  
pp. 1076-1083
Author(s):  
Chenchit Chayachinda ◽  
Chanakarn Kerdklinhom ◽  
Suphaphon Tachawatcharapunya ◽  
Nattha Saisaveoy
Keyword(s):  
Randomized Controlled Trial ◽  
Hepatitis B ◽  
Sexually Transmitted Infections ◽  
Statistical Difference ◽  
Controlled Trial ◽  
Partner Notification ◽  
Thai Women ◽  
Sexually Transmitted ◽  
Blood Tests ◽  
Randomized Controlled

Health education on sexually transmitted infections (STIs), condom use, and partner notification (PN) is required to increase partner evaluation/treatment (PET) rate. To examine this issue, a randomized controlled trial comparing video-based and nurse-led education in women diagnosed with their first STI at the Siriraj Female STI clinic was conducted from March 2015 to March 2017. PN was assessed at two weeks and PET was done at four weeks. Of 330 patients, 225 were included in the analysis (N = 113 and N = 112 for video-based and nurse-led groups, respectively). Each participant reported one partner who needed to be notified. The participants' median age was approximately 30 years old and they had been diagnosed with PID (N = 85), hepatitis B (N = 49), trichomoniasis (N = 45), syphilis (N = 30), and gonorrhea (N = 16). Characteristics were comparable between groups. There was no statistical difference in the PN rates (95.6% vs. 90.2%, p = 0.116), while the PET rate was significantly higher in the nurse-led group (49.6% vs. 67.9%; OR 0.47, 95% CI: 0.27–0.81; p = 0.005). Having endured symptoms for <7 days, being pregnant and detection of STIs during antenatal/pre-operative blood tests were positive predictors of PET (OR: 3.34, 95% CI: 1.81–6.14; 18.70, 95% CI: 5.61–62.31; and 22.07, 95% CI: 6.46–75.41, respectively). In conclusion, video-based education is as effective as nurse-led education in terms of PN rate but results in lower PET.

scholarly journals HERMITAGE-a randomized controlled trial to reduce sexually transmitted infections and HIV risk behaviors among HIV-infected Russian drinkers

Addiction ◽  
2014 ◽  
Vol 110 (1) ◽  
pp. 80-90 ◽  
Author(s):  
Jeffrey H. Samet ◽  
Anita Raj ◽  
Debbie M. Cheng ◽  
Elena Blokhina ◽  
Carly Bridden ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Sexually Transmitted Infections ◽  
Risk Behaviors ◽  
Hiv Risk ◽  
Controlled Trial ◽  
Hiv Risk Behaviors ◽  
Sexually Transmitted ◽  
Randomized Controlled

scholarly journals The Notijoves Project: Protocol for a Randomized Controlled Trial About New Communication Technologies and Gamification to Promote Partner Notification of Sexually Transmitted Infections Among Young People (Preprint)

2018 ◽  
Author(s):  
Dolors Carnicer-Pont ◽  
Eva Loureiro-Varela ◽  
Josep Mª Manresa ◽  
Montse Martinez ◽  
Àngels Avecilla-Palau ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Young People ◽  
Early Diagnosis ◽  
Sexually Transmitted Infections ◽  
Controlled Trial ◽  
Partner Notification ◽  
Communication Technologies ◽  
Web Based ◽  
Sexually Transmitted ◽  
Randomized Controlled

BACKGROUND An increase in sexually transmitted infections (STIs) as well as an increase in the use of new information and communication technologies among young people in Catalonia is the inspiration behind the idea of designing a smartphone app to promote partner notification of STIs. OBJECTIVE The main objective of this study is to design a Web-based tool adapted to smartphones for partner notification of STIs among youth who are 16 to 24 years old. Additionally, the objective is to evaluate the Web-based tool’s role in increasing the patient referral partner notification. METHODS This is a multicenter randomized controlled trial with a proportional stratification of the sample by center and random allocation of participants to the 3 arms of the study (simple Web-based intervention, game Web-based intervention, and control). This study is being conducted by midwives, gynecologists, and physicians in the sexual and reproductive areas of the primary health care centers. RESULTS The primary outcome measure is the number and proportion of partner notifications. Additional outcome measures are the yield of early diagnosis and treatment of those exposed and infected, acceptability, barriers, and preferences for partner notification. Expected results include an increase in the yield of partner notification, early diagnosis and treatment among youth using Web-based interventions compared with those receiving the traditional advice to notify, and a description of sexual networks among those participating in the study. CONCLUSIONS The Notijoves is expected to have a sustainable positive impact in the partner notification practice among youth and contribute to increasing the awareness of STI prevention. INTERNATIONAL REGISTERED REPOR DERR1-10.2196/12896

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