Diagnosis of left atrial tumors by coronary angiography and left ventriculography

Objective Exclusion of the left atrial appendage is proposed to reduce the risk of stroke in patients with atrial fibrillation. The aim of this study was to evaluate the feasibility and efficacy of a fourth-generation atrial exclusion device developed for minimally invasive applications. Methods The novel atrial exclusion device consists of two polymer beams and two elastomeric bands that connect the two beams at either end. Fifteen mongrel dogs were implanted with the device at the base of the left atrial appendage through a median sternotomy and were evaluated at 30 (n = 7), 90 (n = 6), and 180 (n = 2) days after implantation by epicardial echocardiography, left atrial and coronary angiography, gross pathology, and histology. Results Left atrial appendage exclusion was completed without hemodynamic instability. Coronary angiography revealed that the left circumflex artery was patent in all cases. A new endothelial tissue layer developed, as expected, on the occluded orifice of the left atrium. Conclusions This novel atrial exclusion device achieved easy, reliable, and safe exclusion of the left atrial appendage, with favorable histological results in a canine model for up to 6 months. Clinical application could provide a new therapeutic option for reducing the risk of stroke in patients with atrial fibrillation.

Download Full-text

Diagnosis of left atrial myxoma at routine coronary angiography in an asymptomatic patient

Catheterization and Cardiovascular Diagnosis ◽

10.1002/ccd.1810300312 ◽

1993 ◽

Vol 30 (3) ◽

pp. 233-235 ◽

Cited By ~ 1

Author(s):

Andrew W. Hamer ◽

Philip A. Weeks

Keyword(s):

Coronary Angiography ◽

Left Atrial ◽

Asymptomatic Patient ◽

Atrial Myxoma ◽

Left Atrial Myxoma

Download Full-text

Tumors of the heart Incidence and Clinical Importance of Cardiac Tumors in Japan and Operative Technique for Large Left Atrial Tumors

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-2007-1014067 ◽

1990 ◽

Vol 38 (S 2) ◽

pp. 201-204 ◽

Cited By ~ 10

Author(s):

Yukiyasu Sezai

Keyword(s):

Operative Technique ◽

Left Atrial ◽

Clinical Importance ◽

Cardiac Tumors ◽

Atrial Tumors

Download Full-text

How does knowledge of the blood supply to an intracardiac tumour help?

BMJ Case Reports ◽

10.1136/bcr-2018-225900 ◽

2019 ◽

Vol 12 (2) ◽

pp. e225900

Author(s):

Prabha Nini Gupta ◽

Nishant Sagar ◽

Ritesh Ramachandran ◽

Velenurre Rajagopalan Rajeshekharan

Keyword(s):

Coronary Artery ◽

Coronary Angiography ◽

Blood Supply ◽

Right Coronary Artery ◽

Left Atrial ◽

Coronary Angiogram ◽

Left Atrial Myxoma ◽

Cardiac Tumour ◽

Tumour Vascularity ◽

The Right

Myxoma is a common benign tumour found in the heart. On reviewing literature, we found some left atrial myxomas receive blood supply from the right coronary artery. Performing a coronary angiogram in a cardiac tumour has the following uses: (1) it shows the vascularity that can be ligated by the surgeon at operation; (2) if there is a blood supply visible, it may not be an intracardiac thrombus; (3) the coronary angiogram may detect a myxoma even before an echocardiogram does so; (4) some myxomas may bleed into the right atrium or left atrium and this may be seen on coronary angiography. We show here the neovascularity of a left atrial myxoma and its blood supply from the right coronary artery. We recommend that all routine coronary angiograms be reviewed carefully for any signs of tumour vascularity or tumour blush as this would prevent missing early myxomas. Echocardiography is the gold standard for detection of myxomas but literature has a number of intracardiac tumours that were detected only by the tumour blush. Some left atrial tumours have been treated by occluding their blood supply.The absence of a blood supply on coronary angiography could rule out a benign cardiac tumour that usually has a blood supply.

Download Full-text