scholarly journals Thermodynamic Study on Amorphous Form and Crystalline Hydrates of Disodium Guanosine 5′‐Monophosphate by Raman Spectroscopy and FBRM

Author(s):  
Jungsuk Kim ◽  
Joachim Ulrich
2013 ◽  
Vol 63 (3) ◽  
pp. 305-334 ◽  
Author(s):  
Tomaž Einfalt ◽  
Odon Planinšek ◽  
Klemen Hrovat

Abstract The amorphous form of pharmaceutical materials represents the most energetic solid state of a material. It provides advantages in terms of dissolution rate and bioavailability. This review presents the methods of solid- -state amorphization described in literature (supercooling of liquids, milling, lyophilization, spray drying, dehydration of crystalline hydrates), with the emphasis on milling. Furthermore, we describe how amorphous state of pharmaceuticals differ depending on the method of preparation and how these differences can be screened by a variety of spectroscopic (X-ray powder diffraction, solid state nuclear magnetic resonance, atomic pairwise distribution, infrared spectroscopy, terahertz spectroscopy) and calorimetry methods.


Author(s):  
Chima Robert ◽  
Sara J. Fraser-Miller ◽  
Ka̅rlis Be̅rziņš ◽  
Peter O. Okeyo ◽  
Jukka Rantanen ◽  
...  

2005 ◽  
Vol 126 ◽  
pp. 101-105 ◽  
Author(s):  
B. Moulin ◽  
L. Hennet ◽  
D. Thiaudière ◽  
P. Melin ◽  
P. Simon

1965 ◽  
Vol 26 (11) ◽  
pp. 620-626 ◽  
Author(s):  
J.P. Russell
Keyword(s):  

1981 ◽  
Vol 42 (C6) ◽  
pp. C6-776-C6-778
Author(s):  
E. Cazzanelli ◽  
A. Fontana ◽  
G. Mariotto ◽  
F. Rocca ◽  
M. P. Fontana

1983 ◽  
Vol 44 (C10) ◽  
pp. C10-501-C10-503 ◽  
Author(s):  
J. D. Swalen ◽  
J. F. Rabolt

1987 ◽  
Vol 48 (C7) ◽  
pp. C7-761-C7-762
Author(s):  
B. LAVOREL ◽  
G. MILLOT ◽  
R. SAINT-LOUP ◽  
M. L. GONZE ◽  
J. SANTOS ◽  
...  

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