:
Maltodextrins have an increasing number of biomedical and industrial applications due to
their attractive physicochemical properties such as biodegradability and biocompatibility. Herein, we
describe the development of a synthetic pathway and characterization of thiol-responsive maltodextrin
conjugates with dithiomaleimide linkages. 19F NMR studies were also conducted to demonstrate the
exchange dynamics of the dithiomaleimide-functionalized sugar end groups.