ChemInform Abstract: An Efficient, Practical Method for Preparation of Optically Active erythro-Epoxy Secondary Alcohols Using Sharpless Kinetic Resolution of β-Trimethylsilyl Secondary Allylic Alcohols.

ChemInform ◽  
1987 ◽  
Vol 18 (17) ◽  
Author(s):  
Y. KITANO ◽  
T. MATSUMOTO ◽  
Y. TAKEDA ◽  
F. SATO
Keyword(s):  
Kinetic Resolution ◽  
Practical Method ◽  
Optically Active ◽  
Allylic Alcohols ◽  
Secondary Alcohols

scholarly journals Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer

Molecules ◽  
2021 ◽  
Vol 26 (24) ◽  
pp. 7475
Author(s):  
Yipeng You ◽  
Ming Yu Jin ◽  
Guanyu Tao ◽  
Xiangyou Xing
Keyword(s):  
Organic Synthesis ◽  
Hydrogen Transfer ◽  
Kinetic Resolution ◽  
Asymmetric Reduction ◽  
Building Blocks ◽  
Enantioselective Synthesis ◽  
Allylic Alcohols ◽  
Secondary Alcohols ◽  
Highly Efficient ◽  
Reduction Of Ketones

No matter through asymmetric reduction of ketones or kinetic resolution of secondary alcohols, enantioselective synthesis of the corresponding secondary alcohols is challenging when the two groups attached to the prochiral or chiral centers are spatially or electronically similar. For examples, dialkyl (sp3 vs. sp3), diaryl (sp2 vs. sp2), and aryl-alkenyl (sp2 vs. sp2) alcohols are difficult to produce with high enantioselectivities. By exploiting our recently developed Ru-catalysts of minimal stereogenicity, we reported herein a highly efficient kinetic resolution of aryl-alkenyl alcohols through hydrogen transfer. This method enabled such versatile chiral building blocks for organic synthesis as allylic alcohols, to be readily accessed with excellent enantiomeric excesses at practically useful conversions.

Kinetic resolution of N-methyl-2-phenylpyrrolidine by cyclopalladation in the presence of an optically active base

1999 ◽  
Vol 35 (8) ◽  
pp. 1001-1011 ◽  
Author(s):  
V. V. Dunina ◽  
L. G. Kuz'mina ◽  
E. D. Razmyslova ◽  
V. P. Kislyi
Keyword(s):  
Kinetic Resolution ◽  
Optically Active ◽  
Active Base

Kinetic resolution of sterically hindered secondary alcohols catalyzed by aminophosphinite organocatalyst

Tetrahedron ◽  
2018 ◽  
Vol 74 (2) ◽  
pp. 296-302 ◽  
Author(s):  
Nanami Hara ◽  
Shu Fujisawa ◽  
Mizuki Fujita ◽  
Mikako Miyazawa ◽  
Kazuma Ochiai ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Secondary Alcohols ◽  
Sterically Hindered

Optically Active Amines by Enzyme-Catalyzed Kinetic Resolution

Synthesis ◽  
2008 ◽  
Vol 2008 (14) ◽  
pp. 2283-2287 ◽  
Author(s):  
Klaus Ditrich
Keyword(s):  
Kinetic Resolution ◽  
Optically Active

scholarly journals Chemoenzymatic Dynamic Kinetic Resolution of Allylic Alcohols: A Highly Enantioselective Route to Acyloin Acetates.

ChemInform ◽  
2007 ◽  
Vol 38 (52) ◽  
Author(s):  
Krisztian Bogar ◽  
Pilar Hoyos Vidal ◽  
Andres R. Alcantara Leon ◽  
Jan-E. Baeckvall
Keyword(s):  
Kinetic Resolution ◽  
Allylic Alcohols ◽  
Dynamic Kinetic Resolution
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