ChemInform Abstract: Determination of the Absolute Configuration of Organic Compounds by Means of NMR Spectroscopy. Modified Mosher′s Method

ChemInform ◽  
2010 ◽  
Vol 24 (46) ◽  
pp. no-no
Author(s):  
T. KUSUMI
Keyword(s):  
Nmr Spectroscopy ◽  
Organic Compounds ◽  
Absolute Configuration ◽  
The Absolute

Role of Barium(II) in the Determination of the Absolute Configuration of Chiral Amines by1H NMR Spectroscopy

2006 ◽  
Vol 71 (3) ◽  
pp. 1119-1130 ◽  
Author(s):  
Rosa García ◽  
José M. Seco ◽  
Saulo A. Vázquez ◽  
Emilio Quiñoá ◽  
Ricardo Riguera
Keyword(s):  
Nmr Spectroscopy ◽  
Absolute Configuration ◽  
Chiral Amines ◽  
The Absolute

scholarly journals Determination of the Absolute Stereochemistry of Limonene and α-Santalol by Raman Optical Activity Spectroscopy

2012 ◽  
Vol 7 (4) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Akira Sakamoto ◽  
Nao Ohya ◽  
Toshio Hasegawa ◽  
Hiroaki Izumi ◽  
Nakako Tokita ◽  
...  
Keyword(s):  
Organic Compounds ◽  
Optical Activity ◽  
Absolute Configuration ◽  
Natural Compounds ◽  
Vibrational Circular Dichroism ◽  
Raman Optical Activity ◽  
The Absolute ◽  
Circular Dichroïsm ◽  
Absolute Stereochemistry

Determining the absolute stereochemistry of organic compounds in solution remains a challenge. We investigated the use of Raman optical activity (ROA) spectroscopy to address this problem. The absolute configurations of (+)-( R)- and (-)-( S)-limonene were determined by ROA spectroscopy, which can be applied to smaller amounts of sample as compared with vibrational circular dichroism (VCD) spectroscopy. This ROA method was also applied to (+)-( E)-α-santalol and shown to be successful in the determination of the absolute configuration of this compound. ROA spectroscopy shows promise as a useful tool for determining the absolute stereochemistry of many natural compounds.

Determination of the absolute configuration of a secondary alcohol by NMR spectroscopy using difluorodinitrobenzene

1999 ◽  
Vol 40 (51) ◽  
pp. 9081-9084 ◽  
Author(s):  
Ken-ichi Harada ◽  
Youhei Shimizu ◽  
Atsuko Kawakami ◽  
Kiyonaga Fujii
Keyword(s):  
Nmr Spectroscopy ◽  
Absolute Configuration ◽  
Secondary Alcohol ◽  
The Absolute

Determination of the absolute configuration of chiral secondary alcohols; new advances using 13C- and 2D-NMR spectroscopy

1993 ◽  
Vol 4 (7) ◽  
pp. 1527-1532 ◽  
Author(s):  
T. Pehk ◽  
E. Lippmaa ◽  
M. Lopp ◽  
A. Paju ◽  
B.C. Borer ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Absolute Configuration ◽  
2D Nmr ◽  
Secondary Alcohols ◽  
2D Nmr Spectroscopy ◽  
The Absolute

1H—NMR-spektroskopische Bestimmung der diastereomeren Reinheit und der absoluten Konfiguration am Phosphoratom von tButyl-phenyl-phosphinsäure-(—)-menthylester / Determination of the Diastereomeric Purity and the Absolute Configuration at Phosphorus of tButyl-phenyl-phosphinic Acid (—)-Menthyl Ester by Means of 1H NMR Spectroscopy

1977 ◽  
Vol 32 (5) ◽  
pp. 589-593 ◽  
Author(s):  
Reiner Luckenbach ◽  
Hans-H. Bechtolsheimer
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
Absolute Configuration ◽  
1H Nmr Spectroscopy ◽  
Nmr Spectra ◽  
Phosphinic Acid ◽  
H Nmr ◽  
The Absolute ◽  
Diastereomeric Purity

The preparation and separation into diastereomers of tbutyl-phenyl-phosphinic acid (—)-menthyl ester (1a) is reported. The diastereomeric purity as well as the absolute configuration at phosphorus of 1 a can be deduced from the detailed analysis of the 1H NMR spectra of samples of 1a differing in their diastereomer ratios.

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