ChemInform Abstract: Microsphere Formation in a Series of Derivatized α-Amino Acids: Properties, Molecular Modeling, and Oral Delivery of Salmon Calcitonin.

ChemInform ◽  
2010 ◽  
Vol 27 (7) ◽  
pp. no-no
Author(s):  
A. LEONE-BAY ◽  
C. MCINNES ◽  
N. WANG ◽  
F. DEMORIN ◽  
D. ACHAN ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecular Modeling ◽  
Salmon Calcitonin ◽  
Oral Delivery

Microsphere Formation in a Series of Derivatized .alpha.-Amino Acids: Properties, Molecular Modeling, and Oral Delivery of Salmon Calcitonin

1995 ◽  
Vol 38 (21) ◽  
pp. 4257-4262 ◽  
Author(s):  
Andrea Leone-Bay ◽  
Campbell McInnes ◽  
NaiFang Wang ◽  
Frenel DeMorin ◽  
Doug Achan ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecular Modeling ◽  
Salmon Calcitonin ◽  
Oral Delivery

Synthesis, structure elucidation, biological screening, molecular modeling and DNA binding of some Cu(II) chelates incorporating imines derived from amino acids

2016 ◽  
Vol 1103 ◽  
pp. 232-244 ◽  
Author(s):  
Laila H. Abdel-Rahman ◽  
Ahmed M. Abu-Dief ◽  
Mohammed Ismael ◽  
Mounir A.A. Mohamed ◽  
Nahla Ali Hashem
Keyword(s):  
Amino Acids ◽  
Molecular Modeling ◽  
Dna Binding ◽  
Structure Elucidation ◽  
Biological Screening

Potent cyclometallated Pd(ii) antitumor complexes bearing α-amino acids: synthesis, structural characterization, DNA/BSA binding, cytotoxicity and molecular dynamics simulation

2020 ◽  
Vol 49 (42) ◽  
pp. 14891-14907
Author(s):  
Sedigheh Abedanzadeh ◽  
Kazem Karami ◽  
Mostafa Rahimi ◽  
Masoud Edalati ◽  
Mozhgan Abedanzadeh ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Amino Acids ◽  
Molecular Modeling ◽  
Molecular Dynamics Simulation ◽  
Structural Characterization ◽  
Dynamics Simulation ◽  
Bsa Binding ◽  
Modeling Studies ◽  
Molecular Modeling Studies ◽  
Antitumor Complexes

Synthesis, characterization, spectroscopic, biological, and molecular modeling studies on the DNA/BSA binding interactions of new cyclometallated Pd(ii) complexes bearing α-amino acids were investigated.

scholarly journals Complexation Hydrogels for the Oral Delivery of Growth Hormone and Salmon Calcitonin

2010 ◽  
Vol 49 (23) ◽  
pp. 11991-11995 ◽  
Author(s):  
Daniel A. Carr ◽  
Marta Gómez-Burgaz ◽  
Mathilde C. Boudes ◽  
Nicholas A. Peppas
Keyword(s):  
Growth Hormone ◽  
Salmon Calcitonin ◽  
Oral Delivery

Synthesis, Binding Affinity at Glutamic Acid Receptors, Neuroprotective Effects, and Molecular Modeling Investigation of Novel Dihydroisoxazole Amino Acids†

2005 ◽  
Vol 48 (20) ◽  
pp. 6315-6325 ◽  
Author(s):  
Paola Conti ◽  
Marco De Amici ◽  
Giovanni Grazioso ◽  
Gabriella Roda ◽  
Andrea Pinto ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecular Modeling ◽  
Glutamic Acid ◽  
Binding Affinity ◽  
Neuroprotective Effects

N-Acylated .alpha.-Amino Acids as Novel Oral Delivery Agents for Proteins

1995 ◽  
Vol 38 (21) ◽  
pp. 4263-4269 ◽  
Author(s):  
Andrea Leone-Bay ◽  
Noemi Santiago ◽  
Douglas Achan ◽  
Kirin Chaudhary ◽  
Frenel DeMorin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Oral Delivery

scholarly journals Search for new sulfonyl-containing glucophores

2002 ◽  
Vol 74 (7) ◽  
pp. 1227-1233 ◽  
Author(s):  
Jaroslaw Polanski ◽  
Krystyna Jarzembek
Keyword(s):  
Amino Acids ◽  
Molecular Modeling ◽  
Sulfur Atom ◽  
Taste Quality ◽  
Sulfonyl Group ◽  
Modeling Techniques ◽  
Synthetic Routes ◽  
Almost All ◽  
New Compounds

A number of sweeteners contain the sulfur atom and a sulfonyl group. In our current search for new glucophores, several new compounds containing a sulfonyl group were obtained. Synthetic targets have been found both by intuitive modifications of the structural motifs of the known sweet compounds and by the use of molecular modeling techniques. We developed the efficient synthetic routes yielding these compounds and obtained a number of these analogs. We have evaluated the taste quality of the amides and sulfonylated amino acids, finding out that almost all of them are bitter actives. We are now performing basic toxicological tests preceding the systematic taste study within the tetrazoles obtained.

Sign in / Sign up

Export Citation Format

Share Document