ChemInform Abstract: Stereoselective Synthesis of 1,4-Dienes Through Sequential Cross Coupling of (E)-α-Selanylvinylstannanes.

ChemInform ◽  
2010 ◽  
Vol 30 (15) ◽  
pp. no-no
Author(s):  
Yun Ma ◽  
Xian Huang
2020 ◽  
Vol 16 ◽  
pp. 670-673
Author(s):  
Jan Geldsetzer ◽  
Markus Kalesse

The stereoselective synthesis of the (Z)-enamide fragment of chondrochloren (1) is described. A Buchwald-type coupling between amide 3 and (Z)-bromide 4 was used to generate the required fragment. The employed amide 3 comprising three chiral centers was obtained through a seven-step sequence starting from ᴅ-ribonic acid-1,4-lactone. The (Z)-vinyl bromide 4 is accessible in four steps from 4-hydroxybenzaldehyde. The pivotal cross coupling between both fragments was achieved after extensive experimentation with copper(I) iodide, K2CO3 and N,N′-dimethylethane-1,2-diamine.


ChemInform ◽  
2014 ◽  
Vol 45 (33) ◽  
pp. no-no
Author(s):  
Masahiro Miyazawa ◽  
Risa Takehana ◽  
Takao Sanga ◽  
Aoi Hosomori ◽  
Hajime Yokoyama ◽  
...  

2020 ◽  
Vol 85 (9) ◽  
pp. 5863-5871
Author(s):  
Haiyang Cheng ◽  
Xinbo Yao ◽  
Shiwei Yin ◽  
Tao Wang ◽  
Zunting Zhang

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