ChemInform Abstract: Microwave-Assisted Michael Addition of Amides to α,β-Unsaturated Esters under Solvent-Free Conditions.

ChemInform ◽  
2008 ◽  
Vol 39 (36) ◽  
Author(s):  
A. Zare ◽  
A. Hasaninejad ◽  
A. Parhami ◽  
A. R. Moosavi Zare ◽  
A. Khalafi-Nezhad
Keyword(s):  
Michael Addition ◽  
Solvent Free ◽  
Unsaturated Esters ◽  
Microwave Assisted ◽  
Solvent Free Conditions

Zinc oxide-tetrabutylammonium bromide tandem as a highly efficient, green, and reusable catalyst for the Michael addition of pyrimidine and purine nucleobases to α,β-unsaturated esters under solvent-free conditions

2008 ◽  
Vol 86 (4) ◽  
pp. 317-324 ◽  
Author(s):  
Abdolkarim Zare ◽  
Alireza Hasaninejad ◽  
Mohammad Hassan Beyzavi ◽  
Abolfath Parhami ◽  
Ahmad Reza Moosavi Zare ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Michael Addition ◽  
Tetrabutylammonium Bromide ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Efficient Procedure ◽  
Unsaturated Esters ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
The Michael Addition

An efficient procedure for the synthesis of carboacyclic nucleosides via microwave-assisted Michael addition of pyrimidine and purine nucleobases to α,β-unsaturated esters in the presence of catalytic amounts of zinc oxide (ZnO) and tetrabutylammonium bromide (TBAB) is described. The reactions proceed rapidly in good to excellent yields.Key words: ZnO–TBAB, green chemistry, Michael addition, nucleobase, solvent-free, microwave.

Michael addition of phthalimide and saccharin to α,β-unsaturated esters under solvent-free conditions

2007 ◽  
Vol 4 (2) ◽  
pp. 229-237 ◽  
Author(s):  
G. H. Imanzadeh ◽  
A. Khalafi-Nezhad ◽  
A. Zare ◽  
A. Hasaninejad ◽  
A. R. Moosavi Zare ◽  
...  
Keyword(s):  
Michael Addition ◽  
Solvent Free ◽  
Unsaturated Esters ◽  
Solvent Free Conditions

Microwave-Assisted One-Pot Synthesis of α-Fluoro-α,β-Unsaturated Esters under Solvent-Free Conditions

Synlett ◽  
2008 ◽  
Vol 2008 (15) ◽  
pp. 2376-2378
Author(s):  
Xiaochun Yu ◽  
Aishan Ren ◽  
Xiongjun Yang ◽  
Jing Hong
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Unsaturated Esters ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
Solvent Free Conditions

Silicon-based thiourea-mediated and microwave-assisted thio-Michael addition under solvent-free reaction conditions

2011 ◽  
Vol 65 (5) ◽  
Author(s):  
Kamalakannan Prabakaran ◽  
Machindra Gund ◽  
Tae Kim ◽  
Euh Jeong ◽  
Chae Oh ◽  
...  
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Addition Reaction ◽  
Solvent Free ◽  
Michael Addition Reaction ◽  
Reaction Conditions ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
Silicon Based ◽  
Solvent Free Reaction

AbstractSilicon-based thiourea (SiliaBond® Thiourea) (Si-THU), a heterogeneous catalyst, has been applied to the highly selective C-S bond formation via Michael addition of thiols to α,β-unsaturated carbonyl compounds under solvent-free conditions at 55–60°C. The thio-Michael addition products were obtained in an excellent yield under optimised conditions. This methodology involving a metal-free as well as a metal scavenger catalyst has been found to be an alternative method for the thio-Michael addition reaction.

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