ChemInform Abstract: Alkylation and Aldol Reactions of Acyl Derivatives of N-1-(1′-Naphthyl)ethyl-O-tert-butylhydroxylamine: Asymmetric Synthesis of α-Alkoxy-, α-Substituted-β-alkoxy- and α,β-Dialkoxyaldehydes.

ChemInform ◽  
2010 ◽  
Vol 41 (39) ◽  
pp. no-no
Author(s):  
Alexander N. Chernega ◽  
Stephen G. Davies ◽  
Ai M. Flechter ◽  
Christopher J. Goodwin ◽  
David Hepworth ◽  
...  
Tetrahedron ◽  
2010 ◽  
Vol 66 (23) ◽  
pp. 4167-4194 ◽  
Author(s):  
Alexander N. Chernega ◽  
Stephen G. Davies ◽  
Ai M. Fletcher ◽  
Christopher J. Goodwin ◽  
David Hepworth ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1608
Author(s):  
Stephen Lo ◽  
Euphemia Leung ◽  
Bruno Fedrizzi ◽  
David Barker

Quercetin is a flavonoid that is found in many plant materials, including commonly eaten fruits and vegetables. The compound is well known for its wide range of biological activities. In this study, 5-O-acyl derivatives of quercetin were synthesised and assessed for their antiproliferative activity against the HCT116 colon cancer and MDA-MB-231 breast cancer cell lines; and their radical scavenging activity against the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical species. Four derivatives were found to have improved the antiproliferative activity compared to quercetin whilst retaining radical scavenging activity.


1978 ◽  
Vol 9 (52) ◽  
Author(s):  
P. YA. ROMANOVSKII ◽  
A. YU. KRIKIS ◽  
G. I. CHIPENS

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