scholarly journals Nano‐Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles

ChemPhysChem ◽  
2021 ◽  
Vol 22 (14) ◽  
pp. 1408-1408
Author(s):  
Joshua D. Kolbow ◽  
Nathan C. Lindquist ◽  
Christopher T. Ertsgaard ◽  
Daehan Yoo ◽  
Sang‐Hyun Oh
Keyword(s):  
Optical Tweezers ◽  
Single Molecules

Micromanipulation by laser microbeam and optical tweezers: from plant cells to single molecules

2000 ◽  
Vol 198 (3) ◽  
pp. 182-187 ◽  
Author(s):  
K. O. Greulich ◽  
G. Pilarczyk ◽  
A. Hoffmann ◽  
G. Meyer Zu Horste ◽  
B. Schafer ◽  
...  
Keyword(s):  
Optical Tweezers ◽  
Single Molecules ◽  
Plant Cells ◽  
Laser Microbeam

scholarly journals Front Cover: Nano‐Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles (ChemPhysChem 14/2021)

ChemPhysChem ◽  
2021 ◽  
Vol 22 (14) ◽  
pp. 1407-1407
Author(s):  
Joshua D. Kolbow ◽  
Nathan C. Lindquist ◽  
Christopher T. Ertsgaard ◽  
Daehan Yoo ◽  
Sang‐Hyun Oh
Keyword(s):  
Optical Tweezers ◽  
Single Molecules ◽  
Front Cover

scholarly journals New tools to study biophysical properties of single molecules and single cells

2007 ◽  
Vol 79 (1) ◽  
pp. 17-28 ◽  
Author(s):  
Márcio S. Rocha ◽  
Oscar N. Mesquita
Keyword(s):  
Optical Tweezers ◽  
Osmotic Shock ◽  
Single Cells ◽  
Single Molecules ◽  
Numerical Aperture ◽  
Single Individual ◽  
Biophysical Properties ◽  
Individual Object ◽  
Transparent Objects ◽  
Volume Measurements

We present a review on two new tools to study biophysical properties of single molecules and single cells. A laser incident through a high numerical aperture microscope objective can trap small dielectric particles near the focus. This arrangement is named optical tweezers. This technique has the advantage to permit manipulation of a single individual object. We use optical tweezers to measure the entropic elasticity of a single DNA molecule and its interaction with the drug Psoralen. Optical tweezers are also used to hold a kidney cell MDCK away from the substrate to allow precise volume measurements of this single cell during an osmotic shock. This procedure allows us to obtain information about membrane water permeability and regulatory volume increase. Defocusing microscopy is a recent technique invented in our laboratory, which allows the observation of transparent objects, by simply defocusing the microscope in a controlled way. Our physical model of a defocused microscope shows that the image contrast observed in this case is proportional to the defocus distance and to the curvature of the transparent object. Defocusing microscopy is very useful to study motility and mechanical properties of cells. We show here the application of defocusing microscopy to measurements of macrophage surface fluctuations and their influence on phagocytosis.

Optical manipulation of single molecules in the living cell

2014 ◽  
Vol 16 (25) ◽  
pp. 12614-12624 ◽  
Author(s):  
Kamilla Norregaard ◽  
Liselotte Jauffred ◽  
Kirstine Berg-Sørensen ◽  
Lene B. Oddershede
Keyword(s):  
Optical Tweezers ◽  
Living Cell ◽  
Single Molecules ◽  
Optical Manipulation ◽  
Force Measurements

Optical tweezers are the only nano-tools capable of manipulating and performing force-measurements on individual molecules and organelles inside the living cell. We present methodologies for in vivo calibration and exciting recent results.

Nano‐Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles

ChemPhysChem ◽  
2021 ◽  
Author(s):  
Joshua D Kolbow ◽  
Nathan C Lindquist ◽  
Christopher T Ertsgaard ◽  
Daehan Yoo ◽  
Sang-Hyun Oh
Keyword(s):  
Optical Tweezers ◽  
Single Molecules

scholarly journals Collecting single molecules with conventional optical tweezers

2007 ◽  
Vol 75 (1) ◽  
Author(s):  
Wolfgang Singer ◽  
Timo A. Nieminen ◽  
Norman R. Heckenberg ◽  
Halina Rubinsztein-Dunlop
Keyword(s):  
Optical Tweezers ◽  
Single Molecules

Plasmon-Enhanced Optical Tweezers for Single Molecules on and near a Colloidal Silver Nanoaggregate

2019 ◽  
Vol 123 (29) ◽  
pp. 18001-18006 ◽  
Author(s):  
Yasutaka Kitahama ◽  
Misato Funaoka ◽  
Yukihiro Ozaki
Keyword(s):  
Optical Tweezers ◽  
Single Molecules ◽  
Colloidal Silver

Defining the trapping limits of holographical optical tweezers

2004 ◽  
Vol 51 (3) ◽  
pp. 409-414 ◽  
Author(s):  
P. Jordan ◽  
J. Leach ◽  
M. J. Padgett ◽  
J. Cooper ◽  
G. Sinclair
Keyword(s):  
Optical Tweezers

Single molecules in the dark

2009 ◽  
Vol 11 (S1) ◽  
pp. S19-S19 ◽  
Author(s):  
Daniel Evanko
Keyword(s):  
Single Molecules

Multifunctional far-field luminescence nanoscope for studying single molecules and quantum dots

2018 ◽  
Vol 189 (03) ◽  
pp. 312-322 ◽  
Author(s):  
Ivan Yu. Eremchev ◽  
M.Yu. Eremchev ◽  
Andrei V. Naumov
Keyword(s):  
Quantum Dots ◽  
Single Molecules ◽  
Far Field
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