Does noninvasive follicular thyroid neoplasm with papillary-like nuclear features have distinctive features on sonography?

2017 ◽  
Vol 46 (2) ◽  
pp. 139-147 ◽  
Author(s):  
Tamar C. Brandler ◽  
Joseph Yee ◽  
Fang Zhou ◽  
Margaret Cho ◽  
Joan Cangiarella ◽  
...  
Keyword(s):  
Thyroid Neoplasm ◽  
Distinctive Features ◽  
Nuclear Features

scholarly journals Risk of Malignancy in Thyroid Nodules Using the American College of Radiology Thyroid Imaging Reporting and Data System in the NIFTP Era

2018 ◽  
Vol 50 (10) ◽  
pp. 735-737 ◽  
Author(s):  
Pedro Rosario ◽  
Alexandre da Silva ◽  
Maurício Nunes ◽  
Michelle Borges
Keyword(s):  
Thyroid Nodules ◽  
Data System ◽  
Thyroid Neoplasm ◽  
Malignant Tumours ◽  
Thyroid Imaging ◽  
Risk Of Malignancy ◽  
Nuclear Features

AbstractRecently, the American College of Radiology (ACR) proposed a Thyroid Imaging Reporting and Data System (TI-RADS) for thyroid nodules based on ultrasonographic features. It is important to validate this classification in different centres. The present study evaluated the risk of malignancy in solid nodules>1 cm using ACR TI-RADS. The risk of malignancy was defined including noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and after its exclusion from malignant tumours. For the present study, the original images were revised, and each nodule was assigned to one of the TI-RADS levels proposed for solid nodules: TR3, TR4, or TR5. This risk of malignancy was significantly different for the three levels: 1.7%, 11.2%, and 60.6% for TR3, TR4, and TR5, respectively, when NIFTP was included, and 0.6%, 7.9%, and 60.2% for TR3, TR4, and TR5, respectively, when NIFTP was excluded from malignant tumours. The nodules corresponding to NIFTP were classified according to ACR as TR3 in 28.5% of cases, TR4 in 67.8%, and TR5 in only 3.5%. The nodules corresponding to cancer were classified according to ACR as TR3 in only 2.3% of cases, TR4 in 27%, and TR5 in 70.5%. In conclusion, this study shows the validity of the ACR TI-RADS for solid thyroid nodules, even after the exclusion of NIFTP from malignant tumours.

scholarly journals Reply to “Impact of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) on the Outcomes of Lobectomy”

2018 ◽  
Vol 26 (1) ◽  
pp. 307-308 ◽  
Author(s):  
Rajshri M. Gartland ◽  
Carrie C. Lubitz
Keyword(s):  
Thyroid Neoplasm ◽  
Nuclear Features

scholarly journals Clinical and Sonographic Features of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Xiaofeng Ni ◽  
Shangyan Xu ◽  
Benyan Zhang ◽  
Weiwei Zhan ◽  
Wei Zhou
Keyword(s):  
Thyroid Neoplasm ◽  
Nuclear Features

scholarly journals Effect of Implementing the New Diagnostic Criteria for Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features in King Abdulaziz University Hospital

2016 ◽  
Vol 23 (3) ◽  
pp. 31-37
Author(s):  
Fatimah A. Alturkistani ◽  
Murad A. Alturkustani
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Diagnostic Criteria ◽  
University Hospital ◽  
Thyroid Neoplasm ◽  
Papillary Thyroid ◽  
Follicular Variant ◽  
King Abdulaziz University ◽  
Nuclear Features

Pathological diagnosis of follicular variant of papillary thyroid carcinoma has high inter and intra-observer variability among expert pathologists, aff ecting prognosis and management of the disease. A recent study applying strict diagnostic criteria and long-term follow up confi rmed the indolent behavior of a subtype of these tumors. They recommended a nomenclature change to noninvasive follicular thyroid neoplasm with papillary-like nuclear features, refl ecting the low risk of adverse outcomes. We searched the pathology archives of King Abdulaziz University Hospital from 2002-2016 for all cases diagnosed with “follicular variant of papillary thyroid carcinoma”. Clinical data, and imaging fi ndings were retrospectively reviewed. Available pathologyslides were reviewed using the proposed inclusion and exclusion diagnostic criteria. We confi rmed the diagnostic reproducibility of the suggested criteria. Ten out of 37 cases met the diagnostic criteria. Eightadditional patients could have had their diagnosis modifi ed if sufficient tissue samples were available. Follow up data confi rmed the indolent behavior in these cases with no recurrence or adverse outcome. We concluded that application of the new diagnostic criteria for this subtype is reasonable and has major ramifi cations for the diagnosis and management as this will spare unnecessary thyroidectomies, radioactive iodine therapy, and their complications.

scholarly journals Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features

2017 ◽  
Vol 125 (4) ◽  
pp. 292-293
Author(s):  
N. Paul Ohori ◽  
Raja R. Seethala ◽  
Yuri E. Nikiforov
Keyword(s):  
Thyroid Neoplasm ◽  
Molecular Testing ◽  
Young Investigator ◽  
Nuclear Features

Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)

2018 ◽  
Vol 29 (1) ◽  
pp. 68-74 ◽  
Author(s):  
Kyle C. Strickland ◽  
Markus Eszlinger ◽  
Ralf Paschke ◽  
Trevor E. Angell ◽  
Erik K. Alexander ◽  
...  
Keyword(s):  
Thyroid Neoplasm ◽  
Molecular Testing ◽  
Cytologic Diagnosis ◽  
Non Invasive ◽  
Nuclear Features

scholarly journals Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features in Asian Practice: Perspectives for Surgical Pathology and Cytopathology

2018 ◽  
Vol 29 (3) ◽  
pp. 276-288 ◽  
Author(s):  
Andrey Bychkov ◽  
Chan Kwon Jung ◽  
Zhiyan Liu ◽  
Kennichi Kakudo
Keyword(s):  
Surgical Pathology ◽  
Thyroid Neoplasm ◽  
Nuclear Features

scholarly journals An International Interobserver Variability Reporting of the Nuclear Scoring Criteria to Diagnose Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: a Validation Study

2018 ◽  
Vol 29 (3) ◽  
pp. 242-249 ◽  
Author(s):  
Lester D. R. Thompson ◽  
David N. Poller ◽  
Kennichi Kakudo ◽  
Raoul Burchette ◽  
Yuri E. Nikiforov ◽  
...  
Keyword(s):  
Validation Study ◽  
Interobserver Variability ◽  
Thyroid Neoplasm ◽  
Nuclear Features
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