In vitro
 phase I metabolism of three phenethylamines 25D-NBOMe, 25E-NBOMe and 25N-NBOMe using microsomal and microbial models

Katharina Elisabeth Grafinger; Katja Stahl; Andreas Wilke; Stefan König; Wolfgang Weinmann

doi:10.1002/dta.2446

In vitro phase I metabolism of three phenethylamines 25D-NBOMe, 25E-NBOMe and 25N-NBOMe using microsomal and microbial models

Drug Testing and Analysis ◽

10.1002/dta.2446 ◽

2018 ◽

Vol 10 (10) ◽

pp. 1607-1626 ◽

Cited By ~ 5

Author(s):

Katharina Elisabeth Grafinger ◽

Katja Stahl ◽

Andreas Wilke ◽

Stefan König ◽

Wolfgang Weinmann

Keyword(s):

Phase I ◽

Phase I Metabolism

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In Vitro Phase I Metabolism of CRV431, a Novel Oral Drug Candidate for Chronic Hepatitis B

Pharmaceutics ◽

10.3390/pharmaceutics9040051 ◽

2017 ◽

Vol 9 (4) ◽

pp. 51 ◽

Cited By ~ 2

Author(s):

Daniel Trepanier ◽

Daren Ure ◽

Robert Foster

Keyword(s):

Chronic Hepatitis ◽

Hepatitis B ◽

Phase I ◽

Chronic Hepatitis B ◽

Oral Drug ◽

Drug Candidate ◽

Phase I Metabolism

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In vitro phase I metabolism of vinclozolin by human liver microsomes

Xenobiotica ◽

10.1080/00498254.2018.1523485 ◽

2018 ◽

Vol 49 (8) ◽

pp. 895-904

Author(s):

Marycarmen Cruz-Hurtado ◽

Ma de Lourdes López-González ◽

Victor Mondragón ◽

Adolfo Sierra-Santoyo

Keyword(s):

Phase I ◽

Human Liver ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Phase I Metabolism

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Autoantibodies against cytochrome P4501A2 associated with the polyglandular endocrinopathy syndrome inhibit phase I- metabolism of the anticancer drug camptothecin in vitro

Gastroenterology ◽

10.1016/s0016-5085(00)86188-0 ◽

2000 ◽

Vol 118 (4) ◽

pp. A1009

Author(s):

Theresia Thalhammer ◽

Thomas Bachrich ◽

Walter Jaeger ◽

Peter Platzer ◽

Petra Haselmayer ◽

...

Keyword(s):

Phase I ◽

Anticancer Drug ◽

Phase I Metabolism ◽

Cytochrome P4501a2

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In vitro phase I metabolism of gamabufotalin and arenobufagin: Reveal the effect of substituent group on metabolic stability

Fitoterapia ◽

10.1016/j.fitote.2017.06.022 ◽

2017 ◽

Vol 121 ◽

pp. 38-45 ◽

Cited By ~ 4

Author(s):

Yujie Feng ◽

Chao Wang ◽

Xiangge Tian ◽

Xiaokui Huo ◽

Lei Feng ◽

...

Keyword(s):

Phase I ◽

Metabolic Stability ◽

Phase I Metabolism ◽

Substituent Group

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ChemInform Abstract: In vitro Methods for the Investigation of the Phase-I Metabolism

ChemInform ◽

10.1002/chin.200108275 ◽

2001 ◽

Vol 32 (8) ◽

pp. no-no

Author(s):

Sebastian Haertter

Keyword(s):

Phase I ◽

In Vitro Methods ◽

Phase I Metabolism

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In vitro phase I metabolism of the depsipeptide enniatin B

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-011-4964-9 ◽

2011 ◽

Vol 400 (9) ◽

pp. 2889-2901 ◽

Cited By ~ 19

Author(s):

Lada Ivanova ◽

Christiane Kruse Fæste ◽

Silvio Uhlig

Keyword(s):

Phase I ◽

Phase I Metabolism

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Oxidative phase I metabolism of the UV absorber 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV 328) in an in vitro model with human liver microsomes

Toxicology in Vitro ◽

10.1016/j.tiv.2019.06.012 ◽

2019 ◽

Vol 60 ◽

pp. 313-322 ◽

Cited By ~ 4

Author(s):

Heike Denghel ◽

Edgar Leibold ◽

Thomas Göen

Keyword(s):

Phase I ◽

Human Liver ◽

In Vitro Model ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Phase I Metabolism ◽

Uv Absorber ◽

Vitro Model

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5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA

Forensic Toxicology ◽

10.1007/s11419-018-0451-8 ◽

2018 ◽

Vol 37 (1) ◽

pp. 186-196 ◽

Cited By ~ 12

Author(s):

Verena Angerer ◽

Florian Franz ◽

Bjoern Moosmann ◽

Philippe Bisel ◽

Volker Auwärter

Keyword(s):

Phase I ◽

Electronic Cigarettes ◽

Synthetic Cannabinoid ◽

Phase I Metabolism ◽

New Type ◽

Comprehensive Characterization

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In vitro Phase I metabolism of indazole carboxamide synthetic cannabinoid MDMB‐CHMINACA via human liver microsome incubation and high‐resolution mass spectrometry

Drug Testing and Analysis ◽

10.1002/dta.2615 ◽

2019 ◽

Vol 11 (8) ◽

pp. 1264-1276 ◽

Cited By ~ 5

Author(s):

Brandon C. Presley ◽

Barry K. Logan ◽

Susan A. Jansen‐Varnum

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Phase I ◽

Human Liver ◽

Liver Microsome ◽

High Resolution Mass Spectrometry ◽

Human Liver Microsome ◽

Phase I Metabolism ◽

Resolution Mass

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Synthesis, in Silico and in Vitro Study on Phase I Metabolism of the Potent 5-Ht7/5-Ht1a/D2 Receptor Ligand: 4-Fluoron -(1-{2-[2-(Methylsulfanyl)- Phenoxy]Ethyl}Pyrrolidin-3-Yl) Benzene Sulfonamide

Pharmaceutical Chemistry Journal ◽

10.1007/s11094-019-02068-y ◽

2019 ◽

Vol 53 (8) ◽

pp. 713-719

Author(s):

Paulina Kubowicz-Kwaoeny ◽

Kamil Piska ◽

Katarzyna Klaoe ◽

Pawe Zmudzki ◽

Vittorio Canale ◽

...

Keyword(s):

Phase I ◽

In Silico ◽

D2 Receptor ◽

In Vitro Study ◽

Vitro Study ◽

Receptor Ligand ◽

Phase I Metabolism

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