Simultaneous testing for anabolic steroids in human hair specimens collected from various anatomic locations has several advantages when compared with the standard head hair analysis

Author(s):  
Pascal Kintz ◽  
Laurie Gheddar ◽  
Jean‐Sébastien Raul

Author(s):  
Brenda E. Lambert ◽  
Ernest C. Hammond

The purpose of this study was to examine the external structure of four human hair shaft samples with the scanning Electron Microscope (SEM) and to obtain information regarding the chemical composition of hair by using the attached x ray microanalysis unit.The hair samples were obtained from two female subjects. Sample A was taken from a black female and had not undergone any type of chemical processing. Sample B, C, D were taken from a white female, and were natural, processed, and unpigmented, i.e. “gray”, respectively. Sample C had been bleached, tinted, and chemically altered using a permanent wave technique.



1993 ◽  
Vol 61 ◽  
pp. 319
Author(s):  
Atsuhiro Mizuno ◽  
Toshihiko Uematsu ◽  
Masako Nakano ◽  
Kazuhito Kosuge ◽  
Mitsuyoshi Nakashima


2019 ◽  
Vol 11 (4) ◽  
pp. 610-616 ◽  
Author(s):  
Nadia Arbouche ◽  
Jean‐Sebastien Raul ◽  
Delphine Garnier ◽  
Pascal Kintz ◽  
Alice Ameline
Keyword(s):  


2020 ◽  
Vol 44 (6) ◽  
pp. 596-600
Author(s):  
Ting Wang ◽  
Baohua Shen ◽  
Hejian Wu ◽  
Jun Gu ◽  
Min Shen ◽  
...  

Abstract In this study, the relationships between the concentrations of R/S-methamphetamine (MA) and its metabolite R/S-amphetamine (AP), the AP/MA ratio in hair samples, and MA dependence were investigated by performing segmental hair analysis in MA users. Authentic hair samples collected from 10 chronic MA abusers were cut into 1-cm sections (a total of 120 segments). The concentrations of MA and AM enantiomers were quantitatively measured by the LC–MS-MS method. The S-MA concentrations ranged from 1.17 to 256.41 ng/mg and the S-AP concentrations ranged from 0.11 to 23.31 ng/mg in the 120 segments. S-MA and S-AP were the most common analytes identified in hair; no R-MA or R-AP was found. The S-AP/S-MA ratios ranged from 0.03 to 0.32, indicating that the subjects primarily consumed S-MA rather than R-MA or AP. The S-AP/S-MA ratios in the long hair of all chronic MA abusers showed some variation, but there was an overall trend of gradual increase from the distal to the proximal end. This trend was independent of the drug concentrations. Therefore, we could conclude that the AP/MA ratios increased with the duration of MA abuse, and a higher AP/MA ratio suggested high MA dependence. There was no chiral conversion of MA or AP in the hair matrix. The segmental hair analysis showed that all subjects continuously used S-MA, and some users showed an increase in drug dose or the frequency of use.



2001 ◽  
Vol 24 (12) ◽  
pp. 1384-1388 ◽  
Author(s):  
Kazuhiro SAISHO ◽  
Karen S. SCOTT ◽  
Shigeyoshi MORIMOTO ◽  
Yuji NAKAHARA


2013 ◽  
Vol 186 (4) ◽  
pp. 2259-2267 ◽  
Author(s):  
Izabela Michalak ◽  
Paulina Wołowiec ◽  
Katarzyna Chojnacka
Keyword(s):  


2009 ◽  
Vol 184 (1-3) ◽  
pp. 32-36 ◽  
Author(s):  
Min Shen ◽  
Ping Xiang ◽  
Baohua Shen ◽  
Jun Bu ◽  
Mengye Wang
Keyword(s):  


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