scholarly journals A temperature shock can lead to trans‐generational immune priming in the Red Flour Beetle, Tribolium castaneum

2015 ◽  
Vol 5 (6) ◽  
pp. 1318-1326 ◽  
Author(s):  
Hendrik Eggert ◽  
Maike F. Diddens‐de Buhr ◽  
Joachim Kurtz
Keyword(s):  
Tribolium Castaneum ◽  
Red Flour Beetle ◽  
Temperature Shock ◽  
Immune Priming ◽  
Flour Beetle

scholarly journals Paternally derived immune priming for offspring in the red flour beetle,Tribolium castaneum

2010 ◽  
Vol 79 (2) ◽  
pp. 403-413 ◽  
Author(s):  
Olivia Roth ◽  
Gerrit Joop ◽  
Hendrik Eggert ◽  
Jonas Hilbert ◽  
Jens Daniel ◽  
...  
Keyword(s):  
Tribolium Castaneum ◽  
Red Flour Beetle ◽  
Immune Priming ◽  
Flour Beetle

scholarly journals Strain-specific priming of resistance in the red flour beetle, Tribolium castaneum

2008 ◽  
Vol 276 (1654) ◽  
pp. 145-151 ◽  
Author(s):  
Olivia Roth ◽  
Ben M Sadd ◽  
Paul Schmid-Hempel ◽  
Joachim Kurtz
Keyword(s):  
Tribolium Castaneum ◽  
Adaptive Immune System ◽  
Red Flour Beetle ◽  
Initial Exposure ◽  
Immune Priming ◽  
Flour Beetle ◽  
Adaptive Immune ◽  
Molecular Machinery ◽  
Different Strains ◽  
Specific Priming

As invertebrates lack the molecular machinery employed by the vertebrate adaptive immune system, it was thought that they consequently lack the ability to produce lasting and specific immunity. However, in recent years, it has been demonstrated that the immune defence of invertebrates is by far more complicated and specific than previously envisioned. Lasting immunity following an initial exposure that proves protection on a secondary exposure has been shown in several species of invertebrates. This phenomenon has become known as immune priming. In the cases where it is explicitly tested, this priming can also be highly specific. In this study, we used survival assays to test for specific priming of resistance in the red flour beetle, Tribolium castaneum , using bacteria of different degrees of relatedness. Our results suggest an unexpected degree of specificity that even allows for differentiation between different strains of the same bacterium. However, our findings also demonstrate that specific priming of resistance in insects may not be ubiquitous across all bacteria.

scholarly journals Transgenerational developmental effects of immune priming in the red flour beetle Tribolium castaneum

2018 ◽  
Author(s):  
Nora KE Schulz ◽  
Marie Pauline Sell ◽  
Kevin Ferro ◽  
Nico Kleinhölting ◽  
Joachim Kurtz
Keyword(s):  
Tribolium Castaneum ◽  
Adaptive Immune System ◽  
Red Flour Beetle ◽  
Bacterial Strains ◽  
Immune Priming ◽  
Flour Beetle ◽  
Offspring Development ◽  
Direct Benefits ◽  
Filial Generation ◽  
Offspring Generation

AbstractImmune priming, the increased chance to survive a secondary encounter with a pathogen, has been described for many invertebrate species, which lack the classical adaptive immune system of vertebrates. Priming can be specific even for closely related bacterial strains, last up to the entire lifespan of an individual, and in some species, it can also be transferred to the offspring and is then called transgenerational immune priming (TGIP). In the red flour beetle Tribolium castaneum, a pest of stored grains, TGIP has even been shown to be transferred paternally after injection of adult beetles with heat-killed Bacillus thuringiensis.Here we studied whether TGIP in T. castaneum is also transferred to the second filial generation, whether it can also occur after oral and injection priming of larvae and whether it has effects on offspring development. We found that paternal priming with B. thuringiensis does not only protect the first but also the second offspring generation. Also, fitness costs of the immune priming became apparent, when the first filial generation produced fewer offspring. Furthermore, we used two different routes of exposure to prime larvae, either by injecting them with heat-killed bacteria or orally feeding them B. thuringiensis spore culture supernatant. Neither of the parental larval priming methods led to any direct benefits regarding offspring resistance. However, the injections slowed down development of the injected individuals, while oral priming with both a pathogenic and a non-pathogenic strain of B. thuringiensis delayed offspring development.The long-lasting transgenerational nature of immune priming and its impact on offspring development indicate that potentially underlying epigenetic modifications might be stable over several generations. Therefore, this form of phenotypic plasticity might impact pest control and should be considered when using products of bacterial origin against insects.

scholarly journals Transgenerational Developmental Effects of Immune Priming in the Red Flour Beetle Tribolium castaneum

2019 ◽  
Vol 10 ◽  
Author(s):  
Nora K.E. Schulz ◽  
Marie Pauline Sell ◽  
Kevin Ferro ◽  
Nico Kleinhölting ◽  
Joachim Kurtz
Keyword(s):  
Tribolium Castaneum ◽  
Red Flour Beetle ◽  
Immune Priming ◽  
Flour Beetle ◽  
Developmental Effects
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