scholarly journals The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mono- and Biruthenium Polypyridyl Complexes with G-Quadruplex DNA

2017 ◽  
Vol 2017 (33) ◽  
pp. 3953-3960 ◽  
Author(s):  
Clinton G. Mikek ◽  
Venkata R. Machha ◽  
Jake C. White ◽  
Logan R. Martin ◽  
Savannah J. West ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Polypyridyl Complexes ◽  
Quadruplex Dna ◽  
Ligand Structure ◽  
G Quadruplex ◽  
Thermodynamic Effects

scholarly journals The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mononuclear Ruthenium Polypyridyl Complexes with B-DNA

2017 ◽  
Vol 2017 (30) ◽  
pp. 3604-3611 ◽  
Author(s):  
Clinton G. Mikek ◽  
Jesse I. DuPont ◽  
Venkata R. Machha ◽  
Jake C. White ◽  
Logan R. Martin ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Ligand Structure ◽  
Ruthenium Polypyridyl Complexes ◽  
Thermodynamic Effects

scholarly journals The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mononuclear Ruthenium Polypyridyl Complexes with B-DNA

2017 ◽  
Vol 2017 (30) ◽  
pp. 3588-3588
Author(s):  
Clinton G. Mikek ◽  
Jesse I. DuPont ◽  
Venkata R. Machha ◽  
Jake C. White ◽  
Logan R. Martin ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Ligand Structure ◽  
Ruthenium Polypyridyl Complexes ◽  
Thermodynamic Effects

Molecular recognition of parallel quadruplex [d-(TTGGGGT)]4 by mitoxantrone: binding with 1 : 4 stoichiometry leads to telomerase inhibition

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 71652-71661 ◽  
Author(s):  
Tarikere Palakshan Pradeep ◽  
Sweta Tripathi ◽  
Ritu Barthwal
Keyword(s):  
Molecular Recognition ◽  
Thermal Stabilization ◽  
Cancer Drug ◽  
Telomerase Inhibition ◽  
Quadruplex Dna ◽  
Anti Cancer ◽  
G Quadruplex ◽  
Cd Studies

NMR and CD studies show that anti-cancer drug mitoxantrone (MTX) binds to parallel G-quadruplex DNA [d-(TTGGGGT)4] as stacked dimer at grooves leading to increase in thermal stabilization of DNA by ~25 °C and inhibits telomerase with IC50 = 2 μM.

scholarly journals Correction: A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions

RSC Advances ◽  
2018 ◽  
Vol 8 (41) ◽  
pp. 22931-22931
Author(s):  
Dongli Li ◽  
Jin-Qiang Hou ◽  
Wei Long ◽  
Yu-Jing Lu ◽  
Wing-Leung Wong ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Specific Binding ◽  
Amino Group ◽  
Group Interactions ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Recognition Ability

Correction for ‘A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions’ by Dongli Li et al., RSC Adv., 2018, 8, 20222–20227.

Polypyridyl Complexes of Ruthenium(II): Stabilization of G-quadruplex DNA and Inhibition of Telomerase Activity

ChemPlusChem ◽  
2012 ◽  
Vol 77 (7) ◽  
pp. 551-562 ◽  
Author(s):  
Du Liu ◽  
Yanan Liu ◽  
Chuan Wang ◽  
Shuo Shi ◽  
Dongdong Sun ◽  
...  
Keyword(s):  
Telomerase Activity ◽  
Polypyridyl Complexes ◽  
Quadruplex Dna ◽  
G Quadruplex

Molecular recognition of G-quadruplex DNA by Pheophorbide a

2021 ◽  
Author(s):  
China Okamoto ◽  
Atsuya Momotake ◽  
Masami Kobayashi ◽  
Yasuhiko Yamamoto
Keyword(s):  
Molecular Recognition ◽  
Pheophorbide A ◽  
Quadruplex Dna ◽  
G Quadruplex

scholarly journals Chiral Ruthenium(II) Polypyridyl Complexes: Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Cellular Uptake

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e50902 ◽  
Author(s):  
Qianqian Yu ◽  
Yanan Liu ◽  
Chuan Wang ◽  
Dongdong Sun ◽  
Xingcheng Yang ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Telomerase Activity ◽  
Polypyridyl Complexes ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Dna Inhibition
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