An Efficient Synthesis of Achiral and Chiral Cyclic Dehydro-α-Amino Acid Derivatives Through Nucleophilic Addition of Amines to β,γ-Unsaturatedα-Keto Esters

Francisco Palacios; Javier Vicario; Domitila Aparicio

doi:10.1002/ejoc.200600092

An Efficient Synthesis of Achiral and Chiral Cyclic Dehydro-α-Amino Acid Derivatives Through Nucleophilic Addition of Amines to β,γ-Unsaturatedα-Keto Esters

European Journal of Organic Chemistry ◽

10.1002/ejoc.200600092 ◽

2006 ◽

Vol 2006 (12) ◽

pp. 2843-2850 ◽

Cited By ~ 52

Author(s):

Francisco Palacios ◽

Javier Vicario ◽

Domitila Aparicio

Keyword(s):

Amino Acid ◽

Nucleophilic Addition ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Keto Esters

Download Full-text

An Efficient Synthesis of Achiral and Chiral Cyclic Dehydro-α-Amino Acid Derivatives Through Nucleophilic Addition of Amines to β,γ-Unsaturated α-Keto Esters.

ChemInform ◽

10.1002/chin.200641102 ◽

2006 ◽

Vol 37 (41) ◽

Author(s):

Francisco Palacios ◽

Javier Vicario ◽

Domitila Aparicio

Keyword(s):

Amino Acid ◽

Nucleophilic Addition ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Keto Esters

Download Full-text

Facile Synthesis of Enantioenriched Cγ-Tetrasubstituted α-Amino Acid Derivatives via an Asymmetric Nucleophilic Addition/Protonation Cascade

Organic Letters ◽

10.1021/ol200550y ◽

2011 ◽

Vol 13 (9) ◽

pp. 2290-2293 ◽

Cited By ~ 52

Author(s):

Shu-Wen Duan ◽

Jing An ◽

Jia-Rong Chen ◽

Wen-Jing Xiao

Keyword(s):

Amino Acid ◽

Nucleophilic Addition ◽

Amino Acid Derivatives ◽

Facile Synthesis

Download Full-text

ChemInform Abstract: Efficient Synthesis of Modular Amino Acid Derivatives Containing Selenium with Pronounced GPx-Like Activity.

ChemInform ◽

10.1002/chin.201003186 ◽

2010 ◽

Vol 41 (3) ◽

Author(s):

Eduardo E. Alberto ◽

Letiere C. Soares ◽

Jessie H. Sudati ◽

Antonio C. A. Borges ◽

Joao B. T. Rocha ◽

...

Keyword(s):

Amino Acid ◽

Amino Acid Derivatives ◽

Efficient Synthesis

Download Full-text

Efficient Synthesis of γ,δ-Alkynyl-β-amino Acid Derivatives by a New Copper-Catalyzed Amine-Alkyne-Alkyne Addition Reaction

Advanced Synthesis & Catalysis ◽

10.1002/adsc.200800447 ◽

2008 ◽

Vol 350 (14-15) ◽

pp. 2226-2230 ◽

Cited By ~ 23

Author(s):

Lei Zhou ◽

Huan-feng Jiang ◽

Chao-Jun Li

Keyword(s):

Amino Acid ◽

Addition Reaction ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Alkyne Addition

Download Full-text

ChemInform Abstract: Efficient Synthesis of β-Hydroxy-α-amino Acid Derivatives via Direct Catalytic Asymmetric Aldol Reaction of α-Isothiocyanato Imide with Aldehydes.

ChemInform ◽

10.1002/chin.201103131 ◽

2010 ◽

Vol 42 (3) ◽

pp. no-no

Author(s):

Xiaohong Chen ◽

Yin Zhu ◽

Zhen Qiao ◽

Mingsheng Xie ◽

Lili Lin ◽

...

Keyword(s):

Amino Acid ◽

Aldol Reaction ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Asymmetric Aldol ◽

Asymmetric Aldol Reaction ◽

Catalytic Asymmetric

Download Full-text

Silver-Catalyzed Efficient Synthesis of Oxindoles and Pyrroloindolines via α-Aminoalkylation of N -Arylacrylamides with Amino Acid Derivatives

Chemistry - An Asian Journal ◽

10.1002/asia.201701739 ◽

2018 ◽

Vol 13 (5) ◽

pp. 496-499 ◽

Cited By ~ 6

Author(s):

Kyalo Stephen Kanyiva ◽

Sohei Makino ◽

Takanori Shibata

Keyword(s):

Amino Acid ◽

Amino Acid Derivatives ◽

Efficient Synthesis

Download Full-text

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

Angewandte Chemie ◽

10.1002/ange.201201303 ◽

2012 ◽

Vol 124 (19) ◽

pp. 4659-4663 ◽

Cited By ~ 16

Author(s):

Shoko Suzuki ◽

Yuki Kitamura ◽

Sylvain Lectard ◽

Yoshitaka Hamashima ◽

Mikiko Sodeoka

Keyword(s):

Amino Acid ◽

Optically Active ◽

Amino Acid Derivatives ◽

Keto Esters ◽

Catalytic Asymmetric

Download Full-text

Highly Enantioselective γ-Amination of α,β-Unsaturated Acyl Chlorides with Azodicarboxylates: Efficient Synthesis of Chiral γ-Amino Acid Derivatives

Journal of the American Chemical Society ◽

10.1021/ja206819y ◽

2011 ◽

Vol 133 (40) ◽

pp. 15894-15897 ◽

Cited By ~ 67

Author(s):

Li-Tao Shen ◽

Li-Hui Sun ◽

Song Ye

Keyword(s):

Amino Acid ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Acyl Chlorides ◽

Unsaturated Acyl

Download Full-text

Efficient Synthesis of β-Hydroxy-α-Amino Acid Derivatives via Direct Catalytic Asymmetric Aldol Reaction of α-Isothiocyanato Imide with Aldehydes

Chemistry - A European Journal ◽

10.1002/chem.201000284 ◽

2010 ◽

Vol 16 (33) ◽

pp. 10124-10129 ◽

Cited By ~ 32

Author(s):

Xiaohong Chen ◽

Yin Zhu ◽

Zhen Qiao ◽

Mingsheng Xie ◽

Lili Lin ◽

...

Keyword(s):

Amino Acid ◽

Aldol Reaction ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Asymmetric Aldol ◽

Asymmetric Aldol Reaction ◽

Catalytic Asymmetric

Download Full-text

Efficient Synthesis of Enantiopure Tretrahydroisoquinolines by Diastereoselective Intramolecular Heck Reaction Using α-Amino Acid Derivatives

Synthesis ◽

10.1055/s-1994-25690 ◽

1994 ◽

Vol 1994 (12) ◽

pp. 1331-1336 ◽

Cited By ~ 18

Author(s):

L. F. Tietze ◽

O. Burkhardt

Keyword(s):

Amino Acid ◽

Heck Reaction ◽

Amino Acid Derivatives ◽

Efficient Synthesis ◽

Intramolecular Heck Reaction

Download Full-text