scholarly journals Recent Developments in Amide Synthesis: Direct Amidation of Carboxylic Acids and Transamidation Reactions

2013 ◽  
Vol 2013 (33) ◽  
pp. 7453-7465 ◽  
Author(s):  
Rachel M. Lanigan ◽  
Tom D. Sheppard
Keyword(s):  
Carboxylic Acids ◽  
Amide Synthesis ◽  
Recent Developments ◽  
Direct Amidation

scholarly journals Silicon compounds as stoichiometric coupling reagents for direct amidation

2021 ◽  
Author(s):  
Joshua J. Davies ◽  
D. Christopher Braddock ◽  
Paul D. Lickiss
Keyword(s):  
Carboxylic Acids ◽  
Coupling Reagents ◽  
Silicon Compounds ◽  
Direct Amidation

This review covers all the reported use of stoichiometric silicon reagents for direct amidation of carboxylic acids with amines, commencing with the first example in 1969 up until April 2021. 

Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support

2015 ◽  
Vol 17 (5) ◽  
pp. 3157-3163 ◽  
Author(s):  
Andrea Ojeda-Porras ◽  
Alejandra Hernández-Santana ◽  
Diego Gamba-Sánchez
Keyword(s):  
Fatty Acids ◽  
Microwave Irradiation ◽  
Carboxylic Acids ◽  
Silica Gel ◽  
Solid Support ◽  
Secondary Amines ◽  
Primary And Secondary Amines ◽  
Direct Amidation

A highly improved methodology for the direct amidation of carboxylic acids with amines using silica gel as a solid support and catalyst is described. Several examples using aliphatic, aromatic, unsaturated and fatty acids combined with primary and secondary amines are shown.

A multigram-scale lower E-factor procedure for MIBA-catalyzed direct amidation and its application to the coupling of alpha and beta aminoacids

2015 ◽  
Vol 17 (7) ◽  
pp. 4016-4028 ◽  
Author(s):  
Solmaz Fatemi ◽  
Nicolas Gernigon ◽  
Dennis G. Hall
Keyword(s):  
Amino Acids ◽  
Carboxylic Acids ◽  
Direct Amidation

More economical conditions for direct amidation between amines and carboxylic acids, including α- and β-amino acids, have been optimized using the MIBA catalyst (5-methoxy-2-iodophenylboronic acid, 6).

ChemInform Abstract: Direct Amidation of Carboxylic Acids with Tertiary Amines: Amide Formation over Copper Catalysts Through C-N Bond Cleavage.

ChemInform ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. no-no
Author(s):  
Biquan Xiong ◽  
Longzhi Zhu ◽  
Xiaofeng Feng ◽  
Jian Lei ◽  
Tieqiao Chen ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Bond Cleavage ◽  
Copper Catalysts ◽  
Tertiary Amines ◽  
Amide Formation ◽  
Direct Amidation

Repurposing n-butyl stannoic acid as highly efficient catalyst for direct amidation of carboxylic acids with amines

2018 ◽  
Vol 59 (52) ◽  
pp. 4582-4586 ◽  
Author(s):  
Santoshkumar M. Potadar ◽  
Anil S. Mali ◽  
Krishnakant T. Waghmode ◽  
Ganesh U. Chaturbhuj
Keyword(s):  
Carboxylic Acids ◽  
Efficient Catalyst ◽  
Highly Efficient ◽  
Direct Amidation

Atom-economic dehydrogenative amide synthesis via ruthenium catalysis

RSC Advances ◽  
2016 ◽  
Vol 6 (60) ◽  
pp. 55599-55607 ◽  
Author(s):  
Cheng Chen ◽  
Francis Verpoort ◽  
Qiongyou Wu
Keyword(s):  
Amide Synthesis ◽  
Economic Transformations ◽  
Recent Developments ◽  
Ruthenium Catalysis

Recent developments of ruthenium-catalyzed atom-economic transformations for dehydrogenative amide synthesis are reviewed.

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