A new approach to the synthesis of 2-aryl-substituted benzimidazoles, quinazolines, and other related compounds and their antibacterial activity

2012 ◽  
Vol 23 (3) ◽  
pp. 265-275 ◽  
Author(s):  
Renata Los ◽  
Marta Wesołowska-Trojanowska ◽  
Anna Malm ◽  
Monika M. Karpińska ◽  
Joanna Matysiak ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
New Approach ◽  
Related Compounds

ChemInform Abstract: A New Approach to the Synthesis of 2-Aryl-Substituted Benzimidazoles, Quinazolines, and Other Related Compounds and Their Antibacterial Activity.

ChemInform ◽  
2012 ◽  
Vol 43 (37) ◽  
pp. no-no
Author(s):  
Renata Los ◽  
Marta Wesolowska-Trojanowska ◽  
Anna Malm ◽  
Monika M. Karpinska ◽  
Joanna Matysiak ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
New Approach ◽  
Related Compounds

Synthesis, Characterizations, and Biological Effects Study of Some Quinoline Family

2016 ◽  
pp. 160-196
Author(s):  
Messai Amel
Keyword(s):  
Antibacterial Activity ◽  
Single Crystal ◽  
Biological Activities ◽  
Biological Effects ◽  
Diffusion Method ◽  
Quinoline Derivatives ◽  
Single Crystal Diffraction ◽  
Disk Diffusion Method ◽  
New Approach ◽  
Gram Negative

The objective of this work is the synthesis of new quinoline molecules which could have some biological activities. This chapter reported a new approach to the synthesis of some quinoline derivatives. The Baylis-Hillman reaction on 2-methoxy-3-formyl quinoléines derivatives have applied in order to obtain Baylis-Hillman adducts. The products are characterized by FTIR, NMR and X-ray single crystal diffraction .Also, a study of the antibacterial activity of the 3-(2-chloro quinoline)-3-hydroxy-2 methylene propanonitrile products synthesized have been explored. This assessment is made by using the disk diffusion method. The results showed that the 3-(2'-chloroquinoline)-3-hydroxy-2-methylenepropanonitril derivatives present a good antibacterial effectiveness against the strains tested Gram-positive and no antibacterial potency was observed against the stains Gram-negative used in the test.

Juglomycins G-J: Isolation from Streptomycetes and Structure Elucidation

2005 ◽  
Vol 60 (2) ◽  
pp. 183-188 ◽  
Author(s):  
R. P. Maskey ◽  
H. Lessmann ◽  
S. Fotso ◽  
I. Grün-Wollny ◽  
H. Lackner ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Absolute Configuration ◽  
Structure Elucidation ◽  
Mass Spectra ◽  
2D Nmr ◽  
Cd Spectra ◽  
Streptomyces Spp ◽  
Nmr Data ◽  
Related Compounds ◽  
Weak Antibacterial Activity

From the Streptomyces spp. 815 and GW4184, four new 4-juglon-2-ylbutyric acid derivatives, the juglomycins G - J (3a, 4a, 4c, 5c), have been isolated and characterised. The structures were derived from the 1D and 2D NMR data and mass spectra and confirmed by comparison with structurally related compounds. The absolute configuration was deduced from the CD spectra. The new natural products exhibited weak antibacterial activity similar to juglomycin A (5a).

ChemInform Abstract: Synthesis and Antibacterial Activity of 1β-Methyl-2-(5-substituted thiazolidinopyrrolidin-3-ylthio)carbapenems and Related Compounds.

ChemInform ◽  
2010 ◽  
Vol 33 (42) ◽  
pp. no-no
Author(s):  
Chang-Hyun Oh ◽  
Han-Won Cho ◽  
In-Kyu Lee ◽  
Jai-Yang Gong ◽  
Joung-Hoon Choi ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Related Compounds

ChemInform Abstract: Antibacterial Activity of 5-Dialkylaminomethylhydantoins and Related Compounds.

ChemInform ◽  
2010 ◽  
Vol 42 (1) ◽  
pp. no-no
Author(s):  
Fumiko Fujisaki ◽  
Kaori Shoji ◽  
Mari Shimodouzono ◽  
Nobuhiro Kashige ◽  
Fumio Miake ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Related Compounds

ChemInform Abstract: Synthesis and Antibacterial Activity of 1β-Methylcarbapenems Having a 2,2-Disubstituted-1,3-diazabicyclo[3.3.0]octan-4-one Moiety and Related Compounds. Part 3.

ChemInform ◽  
2010 ◽  
Vol 33 (44) ◽  
pp. no-no
Author(s):  
Chang-Hyun Oh ◽  
Hyun-Gu Dong ◽  
Han-Won Cho ◽  
Sung Jin Park ◽  
Joon Hee Hong ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Related Compounds
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