Critical concepts and management recommendations for cutaneous T‐cell lymphoma: A consensus‐based position paper from the Italian Group of Cutaneous Lymphoma

2021 ◽  
Author(s):  
Pier Luigi Zinzani ◽  
Pietro Quaglino ◽  
Silvia Alberti Violetti ◽  
Maria Cantonetti ◽  
Gaia Goteri ◽  
...  
2018 ◽  
Vol 11 (1) ◽  
pp. 234-238 ◽  
Author(s):  
Chris Maminakis ◽  
Arin C. Whitman ◽  
Nahida Islam

We present a case of a patient with cutaneous T-cell lymphoma started on bexarotene 300 mg/m2 due to progressing disease. The patient experienced good clinical response, but unfortunately, she developed rapid and profound hypertriglyceridemia. Although hypertriglyceridemia occurs in high incidence with bexarotene therapy, management recommendations are scarce. Due to the rise in triglycerides, atorvastatin 10 mg daily was initiated in combination with fenofibrate 120 mg daily. Triglycerides continued to increase, so the patient was instructed to take atorvastatin 40 mg, fenofibrate 120 mg, and to hold bexarotene for 2 weeks. After the 2-week break, bexarotene was restarted at 150 mg/m2.


Author(s):  
Lizy Paniagua ◽  
Adrian Subrt ◽  
Bernard Gibson

Microsporum canis cutaneous infection mimicking histopathologically a cutaneous T cell lymphoma is discussed. A 63 year old male presented with pruritic, erythematous thin annular, scaling plaques localized to the forearms, abdomen and left hand. A primary care physician’s biopsy raised concern for a cutaneous lymphoma. At the Dermatology clinic, a KOH and fungal culture suggested a dermatophyte infection caused by Microsporum canis. The patient was treated with oral fluconazole with resolution of most of the lesions and symptoms. This clinical improvement supported the diagnosis of tinea corporis instead of a cutaneous lymphoma. To the best of our knowledge, this is the first reported case of Microsporum canis mimicking cutaneous T-cell lymphoma.


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