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Oral Oncology ◽  
2022 ◽  
Vol 125 ◽  
pp. 105715
Charlotte Le Roy ◽  
Cécile Le Péchoux ◽  
Claire Alapetite ◽  
Ratislav Bahleda ◽  
Carine Ngo ◽  

2022 ◽  
Vol 29 (1) ◽  
pp. 377-382
Jonathan Wallach ◽  
Irini Youssef ◽  
Andrea Leaf ◽  
David Schwartz

A 79-year-old HIV-negative Caucasian man with a medical history of smoking 20 pack-years (quit 40 years prior), early-stage non-small cell lung cancer status post-lobectomy 13 years earlier at an outside hospital without evidence of recurrence, and benign prostatic hypertrophy was diagnosed with synchronous very high-risk prostate adenocarcinoma and early-stage anal basaloid squamous cell carcinoma. He proceeded to undergo concurrent treatment for these tumors, consisting of androgen deprivation therapy, external beam radiation therapy, and a brachytherapy boost for the prostate adenocarcinoma; for the anal carcinoma, he was treated with definitive chemoradiation. Over 3.5 years since the completion of radiotherapy, he remains in clinical and biochemical remission.

С.Н. Антонов ◽  
Ю.Г. Резвов ◽  
В.А. Подольский ◽  
О.Д. Сивкова

To form a multi-beam radiation pattern, it is proposed to use the axial geometry of acousto-optic interaction in paratellurite. In single frequency mode, the use of this geometry for angular scanning is characterized by a dip in the frequency response. Optimization of a multifrequency radio signal makes it possible to effectively divide laser radiation into several beams, while maintaining the fundamental advantages of axial geometry: minimum crystal size and power consumption

Foods ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 91
Naleene Balakrishnan ◽  
Salma Mohamad Yusop ◽  
Irman Abdul Rahman ◽  
Eqbal Dauqan ◽  
Aminah Abdullah

Dried chilli is one of the highly traded spices globally and is well-known for its natural flavour, colour, and unique pungent taste. It is rich in nutrients and has medicinal benefits. During the dehydration and storage process, the proliferation of unwanted microorganisms in dried chilli is unavoidable. Recently, the occurrence of toxigenic fungi and faecal coliforms has been widespread that can cause severe illness and even death. Therefore, sanitation treatment is highly required to decontaminate undesirable microorganisms. Among the common sanitation treatments applied, food irradiation is gaining attention worldwide because of concern for post-harvest loss, foodborne disease, and more stringent regulation in dried chilli trading. Irradiation can successfully preserve dried chilli from pathogenic bacteria with minimal disturbance to critical physical properties, such as pungency and colour. It can also save dried chilli from secondary pollution by storing it into final packing before radiation which helps in distribution to market promptly after treatment. Furthermore, radiation does not leave any chemical residues after the treatment, ensuring the quality and safety of the dried chilli. The efficiency of radiation depends mainly on the initial level of contamination and the persistence of the harmful microorganism. A low irradiation dose is sufficient for dried chili to reduce microbial load to an acceptable level and eliminate pathogens even though a minimum radiation dose of 10 kGy is required for complete sterilization. However, high dosage may affect the colour properties. Gamma radiation, X-ray, and electron beam radiation are the three approved radiation sources for dried chilli in most countries and proven effective for dried chilli preservation. Thus, this review paper highlights the microbial and physical quality properties in gamma radiated dried chillies.

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Nicole Salmen ◽  
Dominic LaBella ◽  
Kenneth Strumpf ◽  
Wiley Douglas Bunn ◽  
Paul Aridgides

Primary signet-ring cell carcinoma of the uterine cervix is a rare subtype of cervical mucinous adenocarcinoma. Approximately 20 cases of primary signet-ring cell carcinoma of the cervix have been reported. Pathologic examination shows that adenocarcinomas with mucin accumulation in intracytoplasmic vacuoles displacing the nucleus indicate signet-ring cell carcinoma. A thorough metastatic workup is needed both for staging and to rule out gastrointestinal tract origin. Due to the rarity of the disease, both the true incidence and optimal management are unknown. Herein, the authors present a case of stage 1B3 primary signet-ring cell cervical carcinoma treated with combined chemotherapy and radiation (including external beam radiation and brachytherapy), followed by resection for residual disease. This case is consistent with limited reports where all surviving patients received surgery as well as 1 surviving patient with bulky disease required with chemoradiation and adjuvant hysterectomy.

Ai Yanagihara ◽  

Abstract In this study, the monolithic integration of LEDs with different emission colors (wavelengths of 543, 573, and 597 nm) with the directional radiation profiles was demonstrated. InGaN/GaN nanocolumn arrays ordered in a triangular lattice were prepared side by side, changing the diameter of the n-GaN nanocolumn (Dn-GaN). The periodic arrangement of the nanocolumns led to the photonic crystal (PC) effect. The photonic band edge wavelength (λB) and the InGaN bandgap were controlled by the Dn-GaN. By controlling λB closely at the bandgap wavelength, the PC effect provided directional beam radiation from the LEDs with radiation angles of approximately ±30°

2021 ◽  
pp. 002203452110538
C. Lei ◽  
Y.H. Wang ◽  
P.X. Zhuang ◽  
Y.T. Li ◽  
Q.Q. Wan ◽  

Biological mineralization is a natural process manifested by living organisms in which inorganic minerals crystallize under the scrupulous control of biomolecules, producing hierarchical organic-inorganic composite structures with physical properties and design that galvanize even the most ardent structural engineer and architect. Understanding the mechanisms that control the formation of biominerals is challenging in the biomimetic engineering of hard tissues. In this regard, the contribution of cryogenic electron microscopy (cryo-EM) has been nothing short of phenomenal. By preserving materials in their native hydrated status and reducing damage caused by ion beam radiation, cryo-EM outperforms conventional transmission electron microscopy in its ability to directly observe the morphologic evolution of mineral precursor phases at different stages of biomineralization with nanoscale spatial resolution and subsecond temporal resolution in 2 or 3 dimensions. In the present review, the development and applications of cryo-EM are discussed to support the use of this powerful technique in dental research. Because of the rapid development of cryogenic sample preparation techniques, direct electron detection, and image-processing algorithms, the last decade has witnessed an exponential increase in the use of cryo-EM in structural biology and materials research. By amalgamating with other analytic techniques, cryo-EM may be used for qualitative and quantitative analyses of the kinetics and thermodynamic mechanisms in which organic macromolecules participate in the transformation of mineral precursors from their original liquid state to amorphous and ultimately crystalline phases. The present review concentrates on the biomineralization of calcium phosphate mineral phases, while that of calcium carbonate, silica, and magnetite is only briefly mentioned. Bioinspired organic matrix–mediated inorganic crystallization strategies are discussed from the perspective of tissue regeneration engineering.

2021 ◽  
pp. 167-172
D. A. Khlanta ◽  
D. S. Romanov

External beam radiation therapy is widely used by doctors around the world as one of the most common form of cancer treatment. The radiotherapy can help reduce the treatment aggression as compared with the surgical intervention in a large number of clinical situations, which ensures that the patient's quality of life will be decreased to a lesser extent in the after-treatment period. However, like the vast majority of anticancer treatments, the radiation therapy has a number of side effects, which are classified into acute radiation reactions and post-radiation injuries. Among them is radiation dermatitis, which is one of the most common adverse reactions to the radiotherapy. This complication manifests as erythema, as well as hyperpigmentation, dry and itchy skin, hair loss. In addition to the obvious negative impact on the patient's quality of life, some of the above factors can result in the development of a secondary skin infection. As one of the most frequent post-radiation complications, radiation dermatitis places radiotherapists before a challenge to reduce the incidence rates of this side effect, as well as to decrease the intensity of its clinical manifestations if it occurs. This challenge suggests the search for targeted drugs aimed to prevent and treat clinical symptoms. To date, dermatocosmetic products that are used to relieve skin manifestations of radiation treatment complications is an alternate option of the effective solution to the problem of radiation dermatitis. In the described clinical case, we assess the experience of using some of the dermatocosmetic products in a patient with a florid form of radiation dermatitis. 

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