Identification of a direct hemolytic effect dependent on the catalytic activity induced by phospholipase-D (dermonecrotic toxin) from brown spider venom

2009 ◽  
Vol 107 (4) ◽  
pp. 655-666 ◽  
Author(s):  
Daniele Chaves-Moreira ◽  
Olga M. Chaim ◽  
Youssef B. Sade ◽  
Kátia S. Paludo ◽  
Luiza H. Gremski ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Phospholipase D ◽  
Spider Venom ◽  
Dermonecrotic Toxin ◽  
Hemolytic Effect ◽  
Brown Spider

Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity

Biochimie ◽  
2008 ◽  
Vol 90 (11-12) ◽  
pp. 1722-1736 ◽  
Author(s):  
J. Kusma ◽  
O.M. Chaim ◽  
A.C.M. Wille ◽  
V.P. Ferrer ◽  
Y.B. Sade ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Phospholipase D ◽  
Spider Venom ◽  
Dermonecrotic Toxin ◽  
Brown Spider

scholarly journals Phospholipase D Toxins of Brown Spider Venom Convert Lysophosphatidylcholine and Sphingomyelin to Cyclic Phosphates

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e72372 ◽  
Author(s):  
Daniel M. Lajoie ◽  
Pamela A. Zobel-Thropp ◽  
Vlad K. Kumirov ◽  
Vahe Bandarian ◽  
Greta J. Binford ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Spider Venom ◽  
Brown Spider ◽  
Cyclic Phosphates

scholarly journals Modulation of membrane phospholipids, the cytosolic calcium influx and cell proliferation following treatment of B16-F10 cells with recombinant phospholipase-D from Loxosceles intermedia (brown spider) venom

Toxicon ◽  
2013 ◽  
Vol 67 ◽  
pp. 17-30 ◽  
Author(s):  
Ana Carolina Martins Wille ◽  
Daniele Chaves-Moreira ◽  
Dilza Trevisan-Silva ◽  
Mariana Gabriel Magnoni ◽  
Marianna Boia-Ferreira ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Phospholipase D ◽  
Calcium Influx ◽  
Cytosolic Calcium ◽  
Spider Venom ◽  
Membrane Phospholipids ◽  
Brown Spider

The relationship between calcium and the metabolism of plasma membrane phospholipids in hemolysis induced by brown spider venom phospholipase-D toxin

2011 ◽  
Vol 112 (9) ◽  
pp. 2529-2540 ◽  
Author(s):  
Daniele Chaves-Moreira ◽  
Fernanda N. Souza ◽  
Rosalvo T.H. Fogaça ◽  
Oldemir C. Mangili ◽  
Waldemiro Gremski ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Phospholipase D ◽  
Spider Venom ◽  
Membrane Phospholipids ◽  
Brown Spider ◽  
The Relationship

Identification, cloning and functional characterization of a novel dermonecrotic toxin (phospholipase D) from brown spider (Loxosceles intermedia) venom

2008 ◽  
Vol 1780 (2) ◽  
pp. 167-178 ◽  
Author(s):  
Marcia Helena Appel ◽  
Rafael Bertoni da Silveira ◽  
Olga Meiri Chaim ◽  
Kátia Sabrina Paludo ◽  
Dilza Trevisan Silva ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Functional Characterization ◽  
Dermonecrotic Toxin ◽  
Brown Spider

Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D

2016 ◽  
Vol 118 (4) ◽  
pp. 726-738 ◽  
Author(s):  
Daniele Chaves-Moreira ◽  
Fábio Rogério de Moraes ◽  
Ícaro Putinhon Caruso ◽  
Olga Meiri Chaim ◽  
Andrea Senff-Ribeiro ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Spider Venom ◽  
Brown Spider

Molecular cloning and functional characterization of two isoforms of dermonecrotic toxin from Loxosceles intermedia (Brown spider) venom gland

Biochimie ◽  
2006 ◽  
Vol 88 (9) ◽  
pp. 1241-1253 ◽  
Author(s):  
Rafael Bertoni da Silveira ◽  
Romine Bachmann Pigozzo ◽  
Olga Meiri Chaim ◽  
Marcia Helena Appel ◽  
Juliana Luporini Dreyfuss ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Functional Characterization ◽  
Venom Gland ◽  
Spider Venom ◽  
Dermonecrotic Toxin ◽  
Brown Spider

Inflammatory events induced by brown spider venom and its recombinant dermonecrotic toxin: A pharmacological investigation

2009 ◽  
Vol 149 (3) ◽  
pp. 323-333 ◽  
Author(s):  
Katia Sabrina Paludo ◽  
Stellee Marcela Petris Biscaia ◽  
Olga Meiri Chaim ◽  
Michel Fleith Otuki ◽  
Katya Naliwaiko ◽  
...  
Keyword(s):  
Pharmacological Investigation ◽  
Spider Venom ◽  
Toxin A ◽  
Dermonecrotic Toxin ◽  
Brown Spider

WITHDRAWN: Inflammatory events induced by brown spider venom and its recombinant dermonecrotic toxin: A pharmacological investigation

2008 ◽  
Author(s):  
Katia Sabrina Paludo ◽  
Stellee Marcela Petris Biscaia ◽  
Olga Meiri Chaim ◽  
Michel Fleith Otuki ◽  
Katya Naliwaiko ◽  
...  
Keyword(s):  
Pharmacological Investigation ◽  
Spider Venom ◽  
Toxin A ◽  
Dermonecrotic Toxin ◽  
Brown Spider

Biological and structural comparison of recombinant phospholipase D toxins from Loxosceles intermedia (brown spider) venom

Toxicon ◽  
2007 ◽  
Vol 50 (8) ◽  
pp. 1162-1174 ◽  
Author(s):  
Rodrigo Otávio S. Ribeiro ◽  
Olga Meiri Chaim ◽  
Rafael Bertoni da Silveira ◽  
Luiza Helena Gremski ◽  
Youssef Bacila Sade ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Spider Venom ◽  
Structural Comparison ◽  
Brown Spider
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