Pyrazole‐1‐carbothioamide as a Potent Precursor for Synthesis of Some New
            N
            ‐heterocycles of Potential Biological Activity

The Kabachnik–Fields reaction, comprising the condensation of an amine, oxo compound and a P-reagent (generally a >P(O)H species or trialkyl phosphite), still attracts interest due to the challenging synthetic procedures and the potential biological activity of the resulting α-aminophosphonic derivatives. Following the success of the first part (Molecules 2012, 17, 12821), here we summarize the synthetic developments in this field accumulated in the last decade. The procedures compiled include catalytic accomplishments as well as catalyst-free and/or solvent-free “greener” protocols. The products embrace α-aminophosphonates, α-aminophosphinates, and α-aminophosphine oxides along with different bis derivatives from the double phospha-Mannich approach. The newer developments of the aza-Pudovik reactions are also included.

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SYNTHESIS OF NOVEL TRYPTOPHAN DERIVATIVES OF POTENTIAL BIOLOGICAL ACTIVITY

Journal of the Chilean Chemical Society ◽

10.4067/s0717-97072009000200018 ◽

2009 ◽

Vol 54 (2) ◽

Cited By ~ 3

Author(s):

RAFAT M MOHAREB ◽

NADIA A LOUCA ◽

GAMAL A ELMEGEED ◽

HANAA Y HANA

Keyword(s):

Biological Activity ◽

Potential Biological Activity ◽

Derivatives Of ◽

Tryptophan Derivatives

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Synthesis and Antibacterial Activities of Some New Heterocycles Attached to Pyridinecarboxamide Moiety of Potential Biological Activity

Heterocycles ◽

10.3987/com-16-13610 ◽

2017 ◽

Vol 94 (4) ◽

pp. 665 ◽

Cited By ~ 1

Author(s):

Nabila A. Kheder ◽

Dalia R. Emam ◽

Hissana Ather

Keyword(s):

Biological Activity ◽

Antibacterial Activities ◽

Potential Biological Activity

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Synthesis and Reactions of Some New Quinoline Thiosemicarbazide Derivatives of Potential Biological Activity

Phosphorus Sulfur and Silicon and the Related Elements ◽

10.1080/10426500701641304 ◽

2008 ◽

Vol 183 (6) ◽

pp. 1323-1343 ◽

Cited By ~ 12

Author(s):

E. M. Keshk ◽

S. I. El-Desoky ◽

M. A. A. Hammouda ◽

A. H. Abdel-Rahman ◽

A. G. Hegazi

Keyword(s):

Biological Activity ◽

Potential Biological Activity ◽

Thiosemicarbazide Derivatives ◽

Derivatives Of

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On the functionalization of benzo[e][2,1]thiazine

Beilstein Journal of Organic Chemistry ◽

10.3762/bjoc.5.42 ◽

2009 ◽

Vol 5 ◽

Cited By ~ 4

Author(s):

Kirill Popov ◽

Tatyana Volovnenko ◽

Julian Volovenko

Keyword(s):

Biological Activity ◽

Reducing Agents ◽

Potential Biological Activity

The reactions of benzo[e][2,1]thiazine-4-chloro-3-carbaldehydes 1 and benzo[e][2,1]thiazine-4-chloro-3-carbonitriles 2 with a number of oxidizing and reducing agents are reported. A number of new, highly functionalized benzo[e][2,1]thiazine derivatives having potential biological activity were synthesized and described.

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