Chiral synthesis of L-[14C]phenylalanine and its incorporation into the renin inhibitor PD 132002

1991 ◽  
Vol 29 (9) ◽  
pp. 1065-1072 ◽  
Author(s):  
Helen T. Lee ◽  
James L. Hicks ◽  
Donald R. Johnson
Keyword(s):  
Renin Inhibitor ◽  
Chiral Synthesis

Aliskiren, a Direct Renin Inhibitor, in Clinical Practice: A New Approach in the Treatment of Hypertension

2010 ◽  
Vol 8 (3) ◽  
pp. 344-362 ◽  
Author(s):  
Elisavet Moutzouri ◽  
Matilda Florentin ◽  
Moses S. Elisaf ◽  
Dimitri P. Mikhailidis ◽  
Evangelos N. Liberopoulos
Keyword(s):  
Clinical Practice ◽  
Renin Inhibitor ◽  
New Approach ◽  
Direct Renin Inhibitor ◽  
Treatment Of Hypertension

Dose-Dependent Effects of the Renin Inhibitor Zankiren HCl After a Single Oral Dose in Mildly Sodium-Depleted Normotensive Subjects

Circulation ◽  
1995 ◽  
Vol 91 (2) ◽  
pp. 330-338 ◽  
Author(s):  
Joël Ménard ◽  
Robert S. Boger ◽  
Denise M. Moyse ◽  
Tam T. Guyene ◽  
Harriet N. Glassman ◽  
...  
Keyword(s):  
Oral Dose ◽  
Single Oral Dose ◽  
Renin Inhibitor ◽  
Normotensive Subjects ◽  
Dose Dependent

H-77: a potent new renin inhibitor. In vitro and in vivo studies

Hypertension ◽  
1982 ◽  
Vol 4 (3) ◽  
pp. 59-69 ◽  
Author(s):  
M. Szelke ◽  
B. J. Leckie ◽  
M. Tree ◽  
A. Brown ◽  
J. Grant ◽  
...  
Keyword(s):  
Renin Inhibitor ◽  
In Vivo Studies

Aliskiren: the first renin inhibitor for clinical treatment

2008 ◽  
Vol 7 (5) ◽  
pp. 399-410 ◽  
Author(s):  
Chris Jensen ◽  
Peter Herold ◽  
Hans Rudolf Brunner
Keyword(s):  
Clinical Treatment ◽  
Renin Inhibitor

scholarly journals A 56,000-dalton renin-binding protein in hog kidney is an endogenous renin inhibitor.

1981 ◽  
Vol 256 (23) ◽  
pp. 12023-12027
Author(s):  
N. Ueno ◽  
H. Miyazaki ◽  
S. Hirose ◽  
K. Murakami
Keyword(s):  
Binding Protein ◽  
Renin Inhibitor ◽  
Hog Kidney

scholarly journals Preliminary X-ray crystallographic data on mouse submaxillary gland renin and renin-inhibitor complexes.

1984 ◽  
Vol 259 (20) ◽  
pp. 12714-12717
Author(s):  
M A Navia ◽  
J P Springer ◽  
M Poe ◽  
J Boger ◽  
K Hoogsteen
Keyword(s):  
Submaxillary Gland ◽  
Crystallographic Data ◽  
Renin Inhibitor ◽  
X Ray ◽  
Mouse Submaxillary Gland
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