Analysis of a major target of the human immune response to cytomegalovirus using monoclonal antibodies

1988 ◽  
Vol 25 (2) ◽  
pp. 237-243 ◽  
Author(s):  
D. Gold ◽  
R. Ashley ◽  
H. Abbo ◽  
L. Corey
1996 ◽  
Vol 64 (12) ◽  
pp. 5171-5177 ◽  
Author(s):  
J A Triccas ◽  
P W Roche ◽  
N Winter ◽  
C G Feng ◽  
C R Butlin ◽  
...  

2021 ◽  
Vol 27 (4) ◽  
pp. 571-572 ◽  
Author(s):  
Roberto Burioni ◽  
Eric J. Topol

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Diane Williamson

This review considers the steps required to evaluate a candidate biodefense vaccine or therapy as it emerges from the research phase, in order to transition it to development. The options for preclinical modelling of efficacy are considered in the context of the FDA’s Animal Rule.


1989 ◽  
Vol 21 (4) ◽  
pp. 386???392 ◽  
Author(s):  
LEONARD H. CALABRESE ◽  
SUSAN M. KLEINER ◽  
BARBARA P. BARNA ◽  
CHRISTINE I. SKIBINSKI ◽  
DONALD T. KIRKENDALL ◽  
...  

2007 ◽  
Vol 1004 ◽  
Author(s):  
David B. Fenner ◽  
David I Rosen ◽  
Anthony A Ferrante ◽  
Amy E Stevens ◽  
Chad E Bigelow ◽  
...  

AbstractDevelopment of field portable apparatus and methods for cytokine assay of human saliva by fluorescent-reporting microarray plates is described. Multiplexed assay of 12 cytokines for minimally-processed saliva is read with a CCD-based imager under LED excitation. Immune responsive cytokines are measured at levels significant for indication of human disease state. The motivational context for the new apparatus development, the general optical design issues, saliva protocol, and image analysis are described.


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