Number of olfactory marker protein-containing receptor cells is influenced by developmental stage of the olfactory bulb

1988 ◽  
Vol 20 (1) ◽  
pp. 84-89 ◽  
Author(s):  
M. I. Chuah ◽  
C. Au
1992 ◽  
Vol 115 (1) ◽  
pp. 132-136 ◽  
Author(s):  
Jon N. Kott ◽  
Haila Vickland ◽  
Xiao Ming Dong ◽  
Lesnick E. Westrum

1991 ◽  
Vol 548 (1-2) ◽  
pp. 140-148 ◽  
Author(s):  
Robin L. Smith ◽  
Harriet Baker ◽  
Kaare Kolstad ◽  
Dennis D. Spencer ◽  
Charles A. Geer

1996 ◽  
Vol 10 (4) ◽  
pp. 221-224 ◽  
Author(s):  
John F. Biedlingmaier ◽  
Philip J. Whelan

The middle turbinate is thought to play a key role in olfaction, and many surgeons have cautioned against removal of the middle turbinate during endoscopic sinus surgery. We reviewed 110 patients having 198 partial middle turbinate resections and found that only one patient complained of postoperative anosmia (0.9%). To further investigate the presence of olfactory tissue on the middle turbinate, 36 sections from 12 endoscopically resected turbinate specimens were stained for olfactory tissue, using olfactory marker protein (OMP). Cadaveric olfactory cleft specimens served as positive controls. Neither olfactory epithelium nor olfactory receptor cells were identified in the surgical specimens. The clinical rarity of anosmia suggests that partial resections must not adversely affect airflow to the olfactory cleft. The histologic data suggest that conservative partial turbinate resections should not affect olfaction directly, either because olfactory tissue is not removed by this maneuver, or because the amount of olfactory tissue in this segment is minimal.


1977 ◽  
Vol 25 (12) ◽  
pp. 1311-1316 ◽  
Author(s):  
G A Monti-Graziadei ◽  
F L Margolis ◽  
J W Harding ◽  
P P Graziadei

The olfactory marker protein has been localized, by means of immunohistochemical techniques in the primary olfactory neurons of mice. The olfactory marker protein is not present in the staminal cells of the olfactory neuroepithelium, and the protein may be regarded as indicative of the functional stage of the neurons. Our data indicate that the olfactory marker protein is present in the synaptic terminals of the olfactory neurons at the level of the olfactory bulb glomeruli. The postsynaptic profiles of both mitral and periglomerular cells are negative.


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