Muscle excursion does not correlate with increased serial sarcomere number after muscle adaptation to stretched tendon transfer

Skeletal muscle has been shown to adjust serial sarcomere number in response to chronic static length changes. However, the adaptive responses to alterations in the dynamic environment are less well defined. The adaptations of the adult mouse tibialis anterior (TA) muscle to altered length and excursion were investigated by surgical transection of the flexor retinaculum. TA moment arm and muscle excursion increased by 38±7 % (mean ± s.e.m.) and fully extended (plantarflexed) muscle length was decreased by 8 % after flexor retinaculum transection. In spite of the significant shortening of the muscle in full plantar- and dorsiflexion, serial sarcomere number decreased by 10±1 % after 2 weeks of recovery. Gait analysis of these transected animals revealed a 14±3 % decrease in dorsiflexion angular velocity after transection. The decrease in angular velocity was less than the increase in moment arm and, as a result, muscle velocity was calculated to increase by 20±4 %. These data suggested that the muscle adapted in response to the underlying change in length, irrespective of the altered excursion or velocity.

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Age does not influence muscle fiber length adaptation to increased excursion

Journal of Applied Physiology ◽

10.1152/jappl.2001.91.6.2466 ◽

2001 ◽

Vol 91 (6) ◽

pp. 2466-2470 ◽

Cited By ~ 6

Author(s):

Thomas J. Burkholder

Keyword(s):

Muscle Fiber ◽

Tibialis Anterior ◽

Fiber Length ◽

Tibialis Anterior Muscle ◽

Age Groups ◽

Muscle Length ◽

Adult Rats ◽

Cross Sectional ◽

Muscle Excursion ◽

Sarcomere Number

Muscle fiber length adaptation to static stretch or shortening depends on age, with sarcomere addition in young muscle being dependent on mobility. Series sarcomere number can also increase in young animals in response to increased muscle excursion, but it is not clear whether adult muscles respond similarly. The ankle flexor retinaculum was transected in neonatal and adult rats to increase tibialis anterior muscle excursion. Sarcomere number in tibialis anterior was determined after 8 wk of adaptation. Muscle moment arm and excursion were increased 30% ( P < 0.01) in both age groups. Muscle cross-sectional area was reduced by 12% ( P < 0.01) in response to the increased mechanical advantage, and this reduction was unaffected by age. Fiber length change was also unaffected by age, with both groups showing a trend ( P < 0.10) for slightly (6%) increased fiber length. Retinaculum transection results in shorter muscle length in all joint configurations, so this trend opposes the fiber length decrease predicted by an adaptation to muscle length and indicates that fiber length is influenced by dynamic mechanical signals in addition to static length.

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Elbow extension tendon transfer

Atlas of the Hand Clinics ◽

10.1016/s1082-3131(03)00037-2 ◽

2002 ◽

Vol 7 (1) ◽

pp. 97-108 ◽

Cited By ~ 1

Author(s):

A VANHEEST

Keyword(s):

Tendon Transfer ◽

Elbow Extension

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Breaking NAD+: investigating NMRK2 as a regulator of muscle adaptation through NAD+ salvage

Endocrine Abstracts ◽

10.1530/endoabs.34.p266 ◽

2014 ◽

Author(s):

Craig Doig ◽

Agnieszka Zielinska ◽

Rachel Fletcher ◽

Emma McCabe ◽

Andrew Philp ◽

...

Keyword(s):

Muscle Adaptation

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Combined Nerve and Tendon Transfer for the Restoration of Hand Function in Individuals With Tetraplegia

Case Medical Research ◽

10.31525/ct1-nct04276181 ◽

2020 ◽

Author(s):

Keyword(s):

Tendon Transfer ◽

Hand Function

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Age-dependent Muscle Adaptation after Chronic Stretch-shortening Contractions in Rats

Aging and Disease ◽

10.14336/ad.2015.0920 ◽

2016 ◽

Vol 7 (1) ◽

pp. 1 ◽

Cited By ~ 9

Author(s):

Erik P. Rader ◽

Kayla N. Layner ◽

Alyssa M. Triscuit ◽

Robert D. Chetlin ◽

James Ensey ◽

...

Keyword(s):

Muscle Adaptation ◽

Age Dependent ◽

Shortening Contractions

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Radial Nerve Palsy: Nerve Transfer Versus Tendon Transfer to Restore Function

Hand ◽

10.1177/1558944720988126 ◽

2021 ◽

pp. 155894472098812

Author(s):

J. Megan M. Patterson ◽

Stephanie A. Russo ◽

Madi El-Haj ◽

Christine B. Novak ◽

Susan E. Mackinnon

Keyword(s):

Radial Nerve ◽

Tendon Transfer ◽

Nerve Palsy ◽

Nerve Transfer ◽

Pinch Strength ◽

Radial Nerve Palsy ◽

Nerve Injuries ◽

Tendon Transfers ◽

Nerve Transfers ◽

Transfer Group

Background: Radial nerve injuries cause profound disability, and a variety of reconstruction options exist. This study aimed to compare outcomes of tendon transfers versus nerve transfers for the management of isolated radial nerve injuries. Methods: A retrospective chart review of 30 patients with isolated radial nerve injuries treated with tendon transfers and 16 patients managed with nerve transfers was performed. Fifteen of the 16 patients treated with nerve transfer had concomitant pronator teres to extensor carpi radialis brevis tendon transfer for wrist extension. Preoperative and postoperative strength data, Disabilities of the Arm, Shoulder, and Hand (DASH) scores, and quality-of-life (QOL) scores were compared before and after surgery and compared between groups. Results: For the nerve transfer group, patients were significantly younger, time from injury to surgery was significantly shorter, and follow-up time was significantly longer. Both groups demonstrated significant improvements in grip and pinch strength after surgery. Postoperative grip strength was significantly higher in the nerve transfer group. Postoperative pinch strength did not differ between groups. Similarly, both groups showed an improvement in DASH and QOL scores after surgery with no significant differences between the 2 groups. Conclusions: The nerve transfer group demonstrated greater grip strength, but both groups had improved pain, function, and satisfaction postoperatively. Patients who present early and can tolerate longer time to functional recovery would be optimal candidates for nerve transfers. Both tendon transfers and nerve transfers are good options for patients with radial nerve palsy.

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Variability in Muscle Adaptation to Electrical Stimulation

International Journal of Sports Medicine ◽

10.1055/s-0032-1321799 ◽

2013 ◽

Vol 34 (06) ◽

pp. 544-553 ◽

Cited By ~ 10

Author(s):

M. Minetto ◽

A. Botter ◽

O. Bottinelli ◽

D. Miotti ◽

R. Bottinelli ◽

...

Keyword(s):

Electrical Stimulation ◽

Muscle Adaptation

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Measuring Vocal Fatigue in Sports Coaches

Journal of Clinical Speech and Language Studies ◽

10.3233/acs-2017-23104 ◽

2017 ◽

Vol 23 (1) ◽

pp. 1-20

Author(s):

Kathy Connaughton ◽

Irena Yanushevskaya

Keyword(s):

Acoustic Analysis ◽

Voice Quality ◽

Professional Sports ◽

Muscle Adaptation ◽

Voice Change ◽

Acoustic Measures ◽

Perceptual Evaluation ◽

Coaching Session ◽

Sports Coaches ◽

Voice Use

Objective: This study explores the immediate impact of prolonged voice use by professional sports coaches. Method: Speech samples including sustained phonation of vowel /a/ and a short read passage were collected from two professional sports coaches. The audio recordings were made within an hour before and after a coaching session, over three sessions. Perceptual evaluation of voice quality was done using the GRBAS scale. The speech samples were subsequently analyzed using Praat. The acoustic measures included fundamental frequency (f0), jitter, shimmer, Harmonics-to-Noise ratio and Cepstral Peak Prominence. Main results: The results of perceptual and acoustic analysis suggest a slight shift towards a tenser phonation post-coaching session, which is a likely consequence of laryngeal muscle adaptation to prolonged voice use. This tendency was similar in sustained vowels and connected speech. Conclusion: Acoustic measures used in this study can be useful to capture the voice change post-coaching session. It is desirable, however, that more sophisticated and robust and at the same time intuitive and easy-to-use tools for voice assessment and monitoring be made available to clinicians and professional voice users.

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