Metered-Dose Inhaler with Spacer versus Nebuliser for Acute Exacerbation of Asthma-A Literature Review

2001 ◽  
Vol 31 (3) ◽  
pp. 189-192
Author(s):  
Hesham S Al-Sallami ◽  
Patrick A Ball ◽  
Andrew K Davey
Keyword(s):  
Literature Review ◽  
Acute Exacerbation ◽  
Dose Inhaler ◽  
Metered Dose Inhaler ◽  
Metered Dose

scholarly journals STUDY OF EFFICACY OF METERED DOSE INHALER (MDI) AND DRY POWDER INHALER (DPI) FOR DELIVERY OF SALBUTAMOL IN TREATMENT OF ACUTE EXACERBATION OF ASTHMA IN PATIENTS, ATTENDING IN TERTIARY CARE HOSPITAL AT, PATNA

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Ajit Kumar ◽  
Raj Narayan Seth
Keyword(s):  
Acute Exacerbation ◽  
Bronchial Asthma ◽  
Tertiary Care ◽  
Dry Powder Inhaler ◽  
Dose Inhaler ◽  
Care Hospital ◽  
Metered Dose Inhaler ◽  
Dry Powder ◽  
Accessory Muscle ◽  
Metered Dose

Objective: Present study was undertaken to compare the efficacy of Metered dose inhaler (MDI) with spacer and with Dry powder inhaler (DPI) for delivery of salbutamol in acute exacerbation of bronchial asthma. It is a randomized controlled trial study. Material and Methods: A total of 78 children in the age group of 6-14 years who presented with a mild or moderate acute exacerbation of asthma were included in the study. Salbutamol dose of 400µg were given to all the children’s by either a MDI with spacer or a DPI in randomized pattern. All the changes in the wheezing and accessory muscle scores, Sa02, and PEFR were noted. Results: Out of 78 children, 42 were assigned to the MDI spacer group and 36 to rotahaler (DPI) group. After receiving treatment, the PEFR improved by about 14% in both the groups. The oxygen saturation increased by 2.1% in both the groups. Within each group, the improvement in PEFR, Sa02, wheeze and accessory muscle score after the treatment was statistically significant. Conclusion: Metered dose inhaler with spacer and Dry powder inhaler are equally effective in delivering salbutamol in therapy of mild to moderate acute exacerbations of bronchial asthma in children between 6-14 years of age Keyword: DPI, Salbutamol, Treatment, Asthma, Children, MDI, PEFR

scholarly journals A COMPARATIVE STUDY OF METERED DOSE INHALER WITH SPACER AND DRY POWDER INHALER FOR DELIVERY OF SALBUTAMOL IN ACUTE EXACERBATIONS OF BRONCHIAL ASTHMA

2021 ◽  
pp. 25-26
Author(s):  
Rakesh Kumar
Keyword(s):  
Acute Exacerbation ◽  
Bronchial Asthma ◽  
Statistical Tests ◽  
Dry Powder Inhaler ◽  
Dose Inhaler ◽  
Metered Dose Inhaler ◽  
Dry Powder ◽  
Accessory Muscle ◽  
Acute Exacerbations ◽  
Metered Dose

Objective: To compare the efficacy of metered dose inhaler with spacer with dry powder inhaler for delivery of salbutamol in acute exacerbation of bronchial asthma Design:Randomized controlled trial in the Setting of Department of Pediatrics, Patna Medical College and Hospital Patna Methods: Children in the age group of 5 - 12 years who presented with a mild or moderate acute exacerbation of asthma were randomized to receive 400 mcg salbutamol by either a MDI with spacer or a DPI. The changes in the wheezing and accessory muscle scores, SaO2, and PEFR were recorded and subjected to statistical tests for significance. Results: Two hundred and fifty-three children were studied; 128 were assigned to the MDI-spacer group and 125 to rotahaler (DPI) group. After receiving treatment, the PEFR improved by about 11% in both the groups. The oxygen saturation increased by 2% in both the groups.Within each group, the improvement in PETR, SaO2, wheeze and accessory muscle score after the treatment was statistically significant. Conclusion: Metered dose inhaler with spacer and dry powder inhaler are equally effective in delivering salbutamol in therapy of mild to moderate acute exacerbations of bronchial asthma in children between 5-12 years of age.

scholarly journals EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA

2021 ◽  
Vol 71 (2) ◽  
pp. 438-41
Author(s):  
Ali Mujtaba Tahir ◽  
Waqas Akhtar ◽  
Salah Ud Din Balooch ◽  
Waqas Ahmed ◽  
Ali Murtaza Samar ◽  
...  
Keyword(s):  
Acute Exacerbation ◽  
Positive Family History ◽  
Favourable Outcome ◽  
Dose Inhaler ◽  
Inadequate Response ◽  
Metered Dose Inhaler ◽  
Adequate Response ◽  
Metered Dose ◽  
Oral Steroids ◽  
Clinical Asthma

Objective: To assess efficacy of salbutamol delivered through metered dose inhaler (MDI) - spacer in paediatric patients with acute exacerbation of asthma. Study Design: Prospective observational study. Place and Duration of Study: Department of Paediatrics, Pakistan Naval Ship, Shifa Hospital, Karachi-Pakistan, from Jan to Dec 2018. Methodology: Ninety Five patients aged ≥6 to ≤12 years, with acute asthma exacerbation were enrolled. Any patient with fever, clinical asthma score (CAS) >7, on home treatment with drugs delivered through nebulization or on oral steroids was excluded. Clinical asthma score recorded on presentation, followed with salbutamol via Metered Dose Inhaler & spacer at dose of 400 µgm (4 x puffs of 100 µgm). Clinical asthma score rechecked after 20 min. Response to salbutamol was then compared in relation to the presenting Clinical asthma score. Results: Out of 95 children, 45 (47.9%) were male & 50 (52.1%) female with 67.4% having positive family history for asthma. Average premedication clinical asthma score was 2.44. Sixty nine (72.9%) patients had an adequate response as they exhibited clinical asthma score of 0 or fall in score of ≥2. Patients with adequate response had average clinical asthma score of 2.07 on presentation in contrast to 3.42 with inadequate response. Conclusion: Salbutamol delivered via Metered Dose Inhaler & spacer at dose of 400 µgm is an effective medication for quick relief in children with acute exacerbation of asthma. Moreover, its administration at a point where exacerbation is not much severe steers us towards more favourable outcome.

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