Invasive fungal sinusitis in a healthy athlete due to long-term anabolic steroid use

2014 ◽  
Vol 124 (8) ◽  
pp. 1756-1759 ◽  
Author(s):  
Irene A. Kim ◽  
Christopher F. Thompson ◽  
Paul A. Kedeshian ◽  
Fernando Palma-Diaz ◽  
Jeffrey D. Suh
2000 ◽  
Vol 79 (4) ◽  
pp. 278-285 ◽  
Author(s):  
Samieh S. Rizk ◽  
Dennis H. Kraus ◽  
Goetz Gerresheim ◽  
Satvinder Mudan

Invasive sinonasal fungal disease is a potentially fatal complication of chemotherapy-induced immunosuppression and neutropenia. We reviewed the outcomes of seven cancer patients who had been diagnosed with invasive fungal sinusitis; six patients had hematologic malignancies and one had breast cancer. At the time of their sinus diagnosis, all patients had been hospitalized and were receiving combination chemotherapy for their underlying malignancy. Impairment of their immune function was characterized by an absolute neutrophil count of less than 1,000/mm3. Aggressive management of their sinonasal fungal disease consisted of surgical debridement and systemic amphotericin B for all patients, and treatment with granulocyte colony-stimulating factor for two patients. Invasive Aspergillus infection was identified in six patients and invasive Candida albicans infection in one. Although the prognosis for these patients was poor and two patients died of the fungal infection, the aggressive treatment strategy resulted in long-term survival for the remaining five patients.


1989 ◽  
Vol 19 (2) ◽  
pp. 103-116 ◽  
Author(s):  
Charles E. Yesalis ◽  
Andrea L. Streit ◽  
Judith R. Vicary ◽  
Karl E. Friedl ◽  
Diane Brannon ◽  
...  

The use of anabolic steroids (AS) by adolescent males is argued to be more widespread than currently acknowledged. Although the long-term physiological and psychological ramifications of use are not well established, current research and anecdotal information suggest that there is reason for concern. In addition, very little is known about the attitudes and behaviors of these adolescent AS users. While the debate concerning the physiological versus the psychological dependence liability of various drugs continues to evolve, there seems to be a consensus that drug dependence is not a per se phenomenon and that the characteristics of dependence differ in accordance with the drug being used. The following article attempts to identify characteristics of the adolescent male AS user and suggests that AS use does have a dependence potential. The AS user population was found to be significantly different from nonusers in several areas such as self-perceptions of health and strength, interest in controlling AS use, and perceptions of peer AS use. The AS user group was also found to contain several subgroups (heavy users [≥ 5 cycles] versus other users, and those who initiated use prior to age sixteen who reported significantly different attitudes and/or behaviors. These differences suggest that prevention efforts will have to focus on different motivations for AS use.


2021 ◽  
Author(s):  
Glen D'Souza ◽  
Theodore Klug ◽  
Tory McKnight ◽  
Blair Barton ◽  
Mike Karsy ◽  
...  

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