Evidence of Nasal Cooling and Sensory Impairments Driving Patient Symptoms With Septal Deviation

2021 ◽  
Author(s):  
Jennifer Malik ◽  
Barak M. Spector ◽  
Zhenxing Wu ◽  
Jennifer Markley ◽  
Songzhu Zhao ◽  
...  
2020 ◽  
Vol 16 (1) ◽  
pp. 28-36
Author(s):  
Maryam Bahrami ◽  
Ghasem Mosayebi ◽  
Ali Ghazavi ◽  
Ali Ganji

Multiple sclerosis is a chronic inflammatory and demyelinating disorder of the central nervous system (CNS) that can cause cognition, mobility, and sensory impairments. Studies have shown that the immune system through inflammation and autoreactive T cells are involved in the progression of MS. The present article aimed to review the potent anti-inflammatory, antioxidant, and immunomodulatory agents that could modulate the immune response in MS. In herbal medicine, various medicinal plants including Olive, Silybum marianum, Grape, Pomegranate peel extract, Nigella sativa, Turmeric, Green tea, Aloysia citrodora, Boswellia papyrifera, Boswellia serrata, Ruta graveolens, and Andrographis paniculata are known with therapeutic benefits in MS patients through immunoregulation and reduction of major symptoms.


2020 ◽  
Vol 31 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Hakan Taşolar ◽  
Mehmet Karataş ◽  
Duygu Demiröz Aslan

2021 ◽  
Vol 18 (3) ◽  
pp. 1-22
Author(s):  
Charlotte M. Reed ◽  
Hong Z. Tan ◽  
Yang Jiao ◽  
Zachary D. Perez ◽  
E. Courtenay Wilson

Stand-alone devices for tactile speech reception serve a need as communication aids for persons with profound sensory impairments as well as in applications such as human-computer interfaces and remote communication when the normal auditory and visual channels are compromised or overloaded. The current research is concerned with perceptual evaluations of a phoneme-based tactile speech communication device in which a unique tactile code was assigned to each of the 24 consonants and 15 vowels of English. The tactile phonemic display was conveyed through an array of 24 tactors that stimulated the dorsal and ventral surfaces of the forearm. Experiments examined the recognition of individual words as a function of the inter-phoneme interval (Study 1) and two-word phrases as a function of the inter-word interval (Study 2). Following an average training period of 4.3 hrs on phoneme and word recognition tasks, mean scores for the recognition of individual words in Study 1 ranged from 87.7% correct to 74.3% correct as the inter-phoneme interval decreased from 300 to 0 ms. In Study 2, following an average of 2.5 hours of training on the two-word phrase task, both words in the phrase were identified with an accuracy of 75% correct using an inter-word interval of 1 sec and an inter-phoneme interval of 150 ms. Effective transmission rates achieved on this task were estimated to be on the order of 30 to 35 words/min.


2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Omar Sabry ◽  
Hazem Dewidar ◽  
Mosaad abdel Aziz ◽  
Amr Elemam ◽  
Ahmed Nassar

Abstract Background Performing nasal surgery on children has been the subject of controversy among surgeons. Specifically, the indications for and timing of septoplasty in children have been debated for the last several decades. In this study, we access the efficacy of the modified Goldman’s technique in dealing with caudal septal deviation in pediatric population suffering from severe nasal obstruction and its effect on nasal functions postoperatively. In this study, 30 pediatric patients suffering from deviated nasal septum who are candidate for septoplasty were included and underwent open septoplasty using modified Goldman’s technique. They were subjected to detailed assessment protocol preoperatively including NOSE scale, anterior rhinomanometry, and CT scans. Follow-up assessment was done at second week postoperative including anterior rhinoscopy and nasal endoscopy and 3 months postoperative including NOSE scale and anterior rhinomanometry. Results There was a statistically significant decrease of the NOSE scale severity to none in 90% of cases. Three months postoperative, all of the patients performed postoperative anterior active rhinomanometry with statistically significant decrease in the postoperative total nasal resistance values with inspiratory values ranging from 0.1 to 0.5 Pa/cm3/s with mean of 0.26 Pa/cm3/s and expiratory nasal resistance values ranging from 0.1 to 0.6 Pa/cm3/s with mean of 0.31 Pa/cm3/s. Conclusions Open septoplasty in children using the modified Goldman’s technique has enabled accurate and conservative approach for correction of nasal septal deviation especially those located in the caudal septal region. The technique also offers a significant reduction of the nasal symptoms postoperatively with marked improvement of the nasal resistance and quality of life in severe cases of deviated nasal septum.


2019 ◽  
Vol 41 (7) ◽  
pp. 823-831 ◽  
Author(s):  
Thomas Radulesco ◽  
Djamel Hazbri ◽  
Patrick Dessi ◽  
Pascal Adalian ◽  
Justin Michel

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