Secondary Prophylaxis of Gastric Variceal Bleeding: A Systematic Review and Network Meta‐analysis

2021 ◽  
Author(s):  
Karim T. Osman ◽  
Tarek Nayfeh ◽  
Ahmed M. Abdelfattah ◽  
Khaled Alabdallah ◽  
Bashar Hasan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Secondary Prophylaxis

scholarly journals S632 Secondary Prophylaxis of Gastric Variceal Bleeding: A Systematic Review and Network Meta-Analysis

2021 ◽  
Vol 116 (1) ◽  
pp. S288-S288
Author(s):  
Karim T. Osman ◽  
Tarek Nayfeh ◽  
Ahmed M. Abdelfattah ◽  
Khaled Alabdallah ◽  
Bashar Hasan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Secondary Prophylaxis

Outcomes of Early Versus Delayed Endoscopy in Cirrhotic Patients With Acute Variceal Bleeding: A Systematic Review With Meta-Analysis

2021 ◽  
Author(s):  
Zhaohui Bai ◽  
Gang Cheng ◽  
Ran Wang ◽  
Dapeng Ma ◽  
Mostafa Ibrahim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Acute Variceal Bleeding ◽  
Cirrhotic Patients

scholarly journals Carvedilol vs endoscopic variceal ligation for primary and secondary prevention of variceal bleeding: Systematic review and meta-analysis

2019 ◽  
Vol 11 (5) ◽  
pp. 464-476 ◽  
Author(s):  
Michael Dwinata ◽  
David Dwi Putera ◽  
Muhamad Fajri Adda’i ◽  
Putra Nur Hidayat ◽  
Irsan Hasan
Keyword(s):  
Systematic Review ◽  
Secondary Prevention ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Endoscopic Variceal Ligation ◽  
Primary And Secondary Prevention

Systematic review with meta-analysis: self-expanding metal stents in patients with cirrhosis and severe or refractory oesophageal variceal bleeding

2015 ◽  
Vol 42 (11-12) ◽  
pp. 1250-1260 ◽  
Author(s):  
A. Marot ◽  
E. Trépo ◽  
C. Doerig ◽  
C. Moreno ◽  
D. Moradpour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Metal Stents ◽  
Self Expanding Metal Stents

scholarly journals Short-course vasoconstrictors are adequate for esophageal variceal bleeding after endoscopic variceal ligation: A systematic review and meta-analysis

2021 ◽  
Vol 104 (3) ◽  
pp. 003685042110317
Author(s):  
Jen-Hao Yeh ◽  
Gin-Ho Lo ◽  
Ru-Yi Huang ◽  
Chih-Wen Lin ◽  
Wen-Lun Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Treatment Failure ◽  
Variceal Bleeding ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Endoscopic Variceal Ligation ◽  
Esophageal Variceal ◽  
Esophageal Variceal Bleeding ◽  
Short Course ◽  
Significant Difference

Endoscopic variceal ligation (EVL) with vasoconstrictors has been recommended for acute esophageal variceal bleeding. However, the optimal duration of vasoconstrictors after EVL is controversial. This systematic review and meta-analysis was conducted to explore the efficacy of short-course vasoconstrictors (≤3 days) versus standard combination (3–5 days). A comprehensive literature review was conducted using the PubMed, Embase, and Cochrane library databases with subsequent meta-analysis. The primary outcomes were 5-day rebleeding, mortality, and treatment failure rates. A risk ratio (RR) with 95% confidence interval is used for outcome comparison. Nine randomized studies with 838 patients were included. The initial hemostasis (96.8% vs 97.4%, p = 0.919), 5-day rebleeding (11.2% vs 8.3%, RR = 1.05, 95% CI = 0.62–1.76), mortality (0 vs 1.3%, RR = 0.48, 95% CI = 0.10–2.39), and treatment failure (7.4% vs 5.9%, RR = 1.10, 95% CI = 0.48–2.49) were similar in both groups. Subgroup analysis suggested EVL alone had no significant difference of 5-day re-bleeding (15.9% vs 7.1%, RR = 2.25, 95% CI = 0.87–5.77), mortality (0 vs 0.7%, RR = 0.71, 95% CI = 0.08–6.03), treatment failure (9.6% vs 6.7%, RR = 1.43, 95% CI = 0.54–3.75) compared to standard combination. Clinical heterogeneity was found for the rebleeding rate for the subgroup during sensitivity analysis. EVL with short-course vasoconstrictors is highly efficacious for esophageal variceal bleeding. Further studies are required to determine the genuine need of subsequent vasoconstrictor after successful EVL.

scholarly journals S1045 EUS-Guided Primary, Secondary Prophylaxis Treatment of Gastric Varices: A Systematic Review With Meta-Analysis

2021 ◽  
Vol 116 (1) ◽  
pp. S495-S496
Author(s):  
Andrew K. Nguyen ◽  
Babu Mohan ◽  
Ray Thomason ◽  
Douglas Adler
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Gastric Varices ◽  
Secondary Prophylaxis
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