Early TIPS versus endoscopic therapy for secondary prophylaxis after management of acute esophageal variceal bleeding in cirrhotic patients: a meta-analysis of randomized controlled trials

2016 ◽  
Vol 31 (9) ◽  
pp. 1519-1526 ◽  
Author(s):  
Shadi Al Halabi ◽  
Tarek Sawas ◽  
Besher Sadat ◽  
Aiyah Jandali ◽  
Hadi Al Halabi ◽  
...  
Keyword(s):  
Variceal Bleeding ◽  
Endoscopic Therapy ◽  
Meta Analysis ◽  
Secondary Prophylaxis ◽  
Controlled Trials ◽  
Esophageal Variceal ◽  
Esophageal Variceal Bleeding ◽  
Randomized Controlled ◽  
Cirrhotic Patients ◽  
Early Tips

scholarly journals Use of nonselective β blockers after variceal eradication in cirrhotic patients undergoing secondary prophylaxis of esophageal variceal bleeding: a critical review of current evidence

2019 ◽  
Vol 10 ◽  
pp. 204062231986269 ◽  
Author(s):  
Xiangbo Xu ◽  
Xiaozhong Guo ◽  
Frank Tacke ◽  
Xiaodong Shao ◽  
Xingshun Qi
Keyword(s):  
Variceal Bleeding ◽  
Secondary Prophylaxis ◽  
Endoscopic Surveillance ◽  
Current Evidence ◽  
Esophageal Variceal ◽  
Esophageal Variceal Bleeding ◽  
Cirrhotic Patients ◽  
Β Blockers ◽  
Variceal Recurrence ◽  
Esophageal Variceal Ligation

Nonselective β blockers (NSBBs) combined with esophageal variceal ligation (EVL) are recommended for secondary prophylaxis of esophageal variceal bleeding (EVB) in cirrhotic patients according to the current practice guidelines and consensus. However, until now, there is a paucity of recommendations regarding the use of NSBBs in cirrhotic patients who achieved variceal eradication. In this review paper, we firstly introduced a case who achieved variceal eradication after additional use of NSBBs for secondary prophylaxis of EVB and then did not require further endoscopic therapy during repeated endoscopic surveillance, and subsequently discuss the importance of NSBBs for secondary prophylaxis of EVB, the effect of NSBBs after variceal eradication, adherence to NSBBs, screening for variceal recurrence, and timing of endoscopic surveillance after variceal eradication.

scholarly journals A Randomized Controlled Study of Fuzheng Huayu Capsule for Prevention of Esophageal Variceal Bleeding in Patients with Liver Cirrhosis

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Jie Gu ◽  
Qin Zhang ◽  
Dongying Xue ◽  
Hong Cai ◽  
Lieming Xu
Keyword(s):  
Variceal Bleeding ◽  
Controlled Trial ◽  
Survival Rates ◽  
Controlled Study ◽  
Esophageal Variceal ◽  
Esophageal Variceal Bleeding ◽  
Randomized Controlled ◽  
Cirrhotic Patients ◽  
Upper Gastrointestinal

To elucidate the role of Fuzheng Huayu Capsule, a herbal formula, in the prevention of esophageal variceal bleeding in cirrhotic patients, a multicenter randomized and placebo-controlled trial was carried out. One hundred forty-six cirrhotic patients with esophageal varices were enrolled to compare the probability of upper gastrointestinal bleeding and survival between Fuzheng Huayu Capsule group and controlled group for the duration of 2 years. The results demonstrated that the FZHYC could effectively reduce the risk of variceal bleeding and improve survival rates for cirrhotic patients with varices, especially the combination of the capsule and Propranolol, which presented a better effect; FZHYC could reduce the varices size in patients with small ones. Its effect may be related to the amelioration of hepatic fibrosis.

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