scholarly journals Long-term follow-up of botulinum toxin therapy for focal hand dystonia: Outcome at 10 years or more

2011 ◽  
Vol 26 (4) ◽  
pp. 750-753 ◽  
Author(s):  
Codrin Lungu ◽  
Barbara I. Karp ◽  
Katharine Alter ◽  
Regina Zolbrod ◽  
Mark Hallett
2013 ◽  
Vol 11 (8) ◽  
pp. 657
Author(s):  
Zoltan Mari ◽  
Gopiga Thanabalasundaram ◽  
Eric Farbman ◽  
Barbara Karp ◽  
Mark Hallett

2002 ◽  
Vol 34 (2) ◽  
pp. 105-110 ◽  
Author(s):  
V. D'Onofrio ◽  
P. Miletto ◽  
G. Leandro ◽  
G. Laquinto

2013 ◽  
Vol 28 (1) ◽  
pp. 33-46 ◽  
Author(s):  
Patrice Berque ◽  
Heather Gray ◽  
Angus McFadyen

Focal hand dystonia (FHD) in musicians is a painless, task-specific motor disorder characterized by involuntary loss of control of individual finger movements. The aim of this study was to investigate the long-term effects of a combined behavioral therapy intervention aimed at normalizing finger movement patterns. METHODS: Eight musicians with FHD had taken part in the 1-year study involving intensive constraint-induced therapy and motor control retraining at slow speed as the interventions. Four of these subjects volunteered to take part in this 4-year follow-up. A quasi-experimental, repeated measures design was used, with 9 testing sessions over 4 years. Video recordings of the subjects playing two pieces were used for data analysis. The Frequency of Abnormal Movements scale (FAM) was the main outcome measure. It was hypothesized that there would be significant differences in FAM scores achieved over the 4-year period. RESULTS: The results from the ANOVA revealed a significant decrease, by approximately 80%, in the number of abnormal movements for both pieces over the 4-year period (F=7.85, df=8, p<0.001). Tukey’s post-hoc test revealed that significant improvements occurred after 6 months of therapy (p-values between p<0.001 and p=0.044). Although the results were not significant between month 12 and follow-up at year 4, the trend revealed that the progress achieved during the first year of intensive retraining was maintained at year 4. CONCLUSIONS: A 1-year period of intensive task-specific retraining may be a successful strategy with long-term, lasting effects for the treatment of musician’s FHD. Results suggest that retraining strategies may need to be carried out for at least 6 months before statistically significant changes are noted.


2019 ◽  
Vol 56 (6) ◽  
pp. 360-364
Author(s):  
Ayse Ipek Akyuz Unsal ◽  
Seyhan B. Özkan ◽  
Sule Ziylan

1995 ◽  
Vol 108 (4) ◽  
pp. A187 ◽  
Author(s):  
P.J. Pasricha ◽  
R. Rai ◽  
W.J. Ravich ◽  
T.R. Hendrix ◽  
A.N. Kalloo

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