Current therapeutic options for Huntington's disease: Good clinical practice versus evidence-based approaches?

2014 ◽  
Vol 29 (11) ◽  
pp. 1404-1413 ◽  
Author(s):  
Annie Killoran ◽  
Kevin M. Biglan
2021 ◽  
Author(s):  
Joaquim J. Ferreira ◽  
Filipe B. Rodrigues ◽  
Gonçalo S. Duarte ◽  
Tiago A. Mestre ◽  
Anne‐Catherine Bachoud‐Levi ◽  
...  

2018 ◽  
Vol 29 (4) ◽  
pp. 395-399
Author(s):  
Wendy Thompson ◽  
Leonardo Essado Rios ◽  
Zbys Fedorowicz ◽  
Yvonne Dailey ◽  
Gail Douglas

Abstract Antibiotics do not cure toothache. This headline message of the United Kingdom’s (UK) Dental Antimicrobial Stewardship (AMS) toolkit’s posters and leaflets is aimed at patients; clinicians are expected to know this already. Evidence based clinical guidelines exist to set clear standards for good clinical practice yet there are barriers to compliance. The national AMS audit tool is designed for clinicians to review their management of acute dental conditions, including but not limited to the prescription of antibiotics. In this article we aim to help dental teams protect their patients and themselves from adverse events related to antibiotic prescription. It explores the emergent problem of Clostridium difficile, antibiotic resistance and severe sepsis, and considers some of the barriers, which clinicians have suggested, contribute to the unjustified prescription of antibiotics. Dentists must weigh the risks against the benefits before prescribing any antibiotic.


2019 ◽  
Vol 27 (8) ◽  
pp. 1215-1224
Author(s):  
Felicity Wadrup ◽  
◽  
Simon Holden ◽  
Rhona MacLeod ◽  
Zosia Miedzybrodzka ◽  
...  

This handbook is written for clinical and healthcare research students as well as graduates who wish to work in clinical and healthcare research. It provides simple instructions on the legislative requirements as well as the practical requirements of commissioning, conducting, analysing and reporting research for those in clinical or healthcare practice, and education/training. The handbook outlines the underpinning concepts governing each topic. It takes the researcher through the steps from general good clinical practice in healthcare research, through the process and management of research in a practical yet evidence based manner. There is wide coverage of topics pertaining to several areas of healthcare research, not commonly found in a single text.


Author(s):  
J. David Kinzie

In setting treatment goals, the patient’s cultural values and goals, as well as diagnosis, need to be considered by the clinician. Psychiatrists are urged to use the Cultural Formulation Interview of the DSM-5 to aide in assessing patients. With the impacts of globalization and ubiquitous television viewing influencing the culture of the refugees and immigrants, clearly their cultures are in flux and not static, after they arrive in the new country. Doctors and medical approaches are well known to refugees and immigrants. However, they may experience resistance and fear on referral to psychiatrists for reasons of stigma. A sensitive medical approach can help reduce the resistance and fear on the part of the refugee. When a relationship forms, psychosocial issues can be addressed. Treatment guidelines for evidence-based treatments for Western patients exist, but these should be individualized for refugees with individual goals. Good clinical practice and cultural understanding must meet the patient’s personal goals.


2015 ◽  
Vol 21 (3) ◽  
pp. 169-178 ◽  
Author(s):  
Daniel Zielonka ◽  
Michal Mielcarek ◽  
G. Bernhard Landwehrmeyer

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