scholarly journals Pharmacological treatment of chorea in Huntington's disease-good clinical practice versus evidence-based guideline

2013 ◽  
Vol 28 (8) ◽  
pp. 1030-1033 ◽  
Author(s):  
Ralf Reilmann
Keyword(s):  
Clinical Practice ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Pharmacological Treatment ◽  
Good Clinical Practice ◽  
Evidence Based ◽  
Evidence Based Guideline

scholarly journals Plain Language Summary: Benign Paroxysmal Positional Vertigo

2017 ◽  
Vol 156 (3) ◽  
pp. 417-425
Author(s):  
Neil Bhattacharyya ◽  
Deena B. Hollingsworth ◽  
Kathryn Mahoney ◽  
Sarah O’Connor
Keyword(s):  
Quality Improvement ◽  
Clinical Practice ◽  
Clinical Practice Guideline ◽  
Benign Paroxysmal Positional Vertigo ◽  
Evidence Based ◽  
Plain Language ◽  
Positional Vertigo ◽  
Effective Diagnosis ◽  
Evidence Based Guideline ◽  
Paroxysmal Positional Vertigo

Objective. This plain language summary serves as an overview in explaining benign paroxysmal positional vertigo, abbreviated BPPV. This summary applies to patients ≥18 years old with a suspected or potential diagnosis of BPPV and is based on the 2017 “Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).” The evidence-based guideline includes research to support more effective diagnosis and treatment of BPPV. The guideline was developed as a quality improvement opportunity for managing BPPV by creating clear recommendations to use in medical practice.

A MDS Evidence‐Based Review on Treatments for Huntington's Disease

2021 ◽  
Author(s):  
Joaquim J. Ferreira ◽  
Filipe B. Rodrigues ◽  
Gonçalo S. Duarte ◽  
Tiago A. Mestre ◽  
Anne‐Catherine Bachoud‐Levi ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Evidence Based

The Pharmacological Treatment of Refractory OCD

2017 ◽  
Author(s):  
Christopher Pittenger
Keyword(s):  
Clinical Practice ◽  
Pharmacological Treatment ◽  
Evidence Base ◽  
Evidence Based ◽  
Second Line ◽  
First Line ◽  
Substantial Fraction ◽  
Meaningful Improvement ◽  
Residual Symptoms ◽  
Glutamate Neurotransmission

Evidence-based interventions for OCD, both psychotherapeutic and pharmacological, are of benefit to many. However, even when optimally deployed, first- and second-line treatments leave a substantial fraction of patients—perhaps as many as 20% to 25%—without meaningful improvement. Furthermore, many who are classified as “responders” to first- and second-line treatments continue to have substantial residual symptoms and attendant morbidity. This chapter reviews various pharmacological strategies that have been used for the treatment of refractory OCD, including agents targeting serotonin, dopamine, and glutamate neurotransmission. Although the evidence base supporting the use of these agents is not as robust as it is for first-line interventions, many have shown promise in some studies. The prevalence of refractory OCD symptoms means that such pharmacological strategies must frequently be considered in clinical practice, despite the lack of definitive guidance from controlled studies.

Safe chemotherapy: Clinicians driving technology and not the other way around.

2012 ◽  
Vol 30 (34_suppl) ◽  
pp. 183-183
Author(s):  
Vishal Kukreti ◽  
Roxanne Cosby ◽  
Annie Cheung ◽  
Marie Hamasoor ◽  
Sherrie Hertz ◽  
...  
Keyword(s):  
Clinical Practice ◽  
System Integration ◽  
Quality Care ◽  
Management Strategies ◽  
User Involvement ◽  
Clinical Work ◽  
Future Research ◽  
Evidence Based ◽  
Unanticipated Consequences ◽  
Evidence Based Guideline

183 Background: Although information technology (IT) has the potential to improve the quality and safety of patient care, introduction into the clinical work flow may create unanticipated consequences. IT solutions such as computerized physician order entry (CPOE) are often designed and executed without end-user involvement. An evidence based guideline for systemic treatment (ST) CPOE was developed. The guideline looks at the features, functionalities and components of a ST CPOE system required to ensure safe and high-quality care. Methods: The guideline was developed by an interdisciplinary panel of physicians, nurses, pharmacists, methodologists, IT specialists, and human factors experts. A systematic review was conducted of the available clinical and technology literature and key informant interviews were conducted. Role-specific CPOE functionalities were process mapped for physicians, nurses and pharmacists. Two expert panels (i.e., clinical and supporting tools) were convened to review the information and provide feedback on guideline content. The guideline was also reviewed externally by content experts from provincial, national and international organizations. Results: The resulting evidence-based guideline focused on two distinct yet interconnected parts: clinical practice (e.g., error prevention, unanticipated consequences, impact on practice, clinical decision support), and technology requirements (e.g., usability features, system integration, effective alerts, audit logs, regimen building). The recommendations also highlight the importance of change management strategies and clinician engagement. Conclusions: This innovative guideline provides an approach to technology evaluation focusing on clinical practice needs driving IT solutions. Future research to help standardize design and usability of such systems is necessary. The non-vendor specific recommendations can be used as the foundation for evaluation of ST CPOE systems to reduce errors, improve safety, and support clinical practice. The application of the recommendations as an assessment of ST CPOE system guideline concordance will also be valuable.

scholarly journals Plain Language Summary: Earwax (Cerumen Impaction)

2017 ◽  
Vol 156 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Helene J. Krouse ◽  
Anthony E. Magit ◽  
Sarah O’Connor ◽  
Seth R. Schwarz ◽  
Sandra A. Walsh
Keyword(s):  
Health Care ◽  
Clinical Practice ◽  
Health Care Providers ◽  
Medical Practice ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Evidence Based ◽  
Care Providers ◽  
Plain Language ◽  
Evidence Based Guideline

This plain language summary serves as an overview in explaining earwax (cerumen). The summary applies to patients older than 6 months with a clinical diagnosis of earwax impaction and is based on the 2017 update of the Clinical Practice Guideline: Earwax (Cerumen Impaction). The evidence-based guideline includes research that supports diagnosis and treatment of earwax impaction. The guideline was developed to improve care by health care providers for managing earwax impaction by creating clear recommendations to use in medical practice.

scholarly journals I’ve got Toothache, I need Antibiotics: a UK Perspective on Rational Antibiotic Prescribing by Dentists

2018 ◽  
Vol 29 (4) ◽  
pp. 395-399
Author(s):  
Wendy Thompson ◽  
Leonardo Essado Rios ◽  
Zbys Fedorowicz ◽  
Yvonne Dailey ◽  
Gail Douglas
Keyword(s):  
Antibiotic Resistance ◽  
Severe Sepsis ◽  
Clinical Practice ◽  
Clostridium Difficile ◽  
Antibiotic Prescription ◽  
Good Clinical Practice ◽  
Antibiotic Prescribing ◽  
Evidence Based ◽  
Audit Tool ◽  
Dental Conditions

Abstract Antibiotics do not cure toothache. This headline message of the United Kingdom’s (UK) Dental Antimicrobial Stewardship (AMS) toolkit’s posters and leaflets is aimed at patients; clinicians are expected to know this already. Evidence based clinical guidelines exist to set clear standards for good clinical practice yet there are barriers to compliance. The national AMS audit tool is designed for clinicians to review their management of acute dental conditions, including but not limited to the prescription of antibiotics. In this article we aim to help dental teams protect their patients and themselves from adverse events related to antibiotic prescription. It explores the emergent problem of Clostridium difficile, antibiotic resistance and severe sepsis, and considers some of the barriers, which clinicians have suggested, contribute to the unjustified prescription of antibiotics. Dentists must weigh the risks against the benefits before prescribing any antibiotic.

scholarly journals Plain Language Summary: Hoarseness (Dysphonia)

2018 ◽  
Vol 158 (3) ◽  
pp. 427-431 ◽  
Author(s):  
Helene J. Krouse ◽  
Charles (Charlie) W. Reavis ◽  
Robert J. Stachler ◽  
David O. Francis ◽  
Sarah O’Connor
Keyword(s):  
Quality Of Care ◽  
Clinical Practice ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Age Groups ◽  
Evidence Based ◽  
Plain Language ◽  
Evidence Based Guideline

This plain language summary for patients serves as an overview in explaining hoarseness (dysphonia). The summary applies to patients in all age groups and is based on the 2018 “Clinical Practice Guideline: Hoarseness (Dysphonia) (Update).” The evidence-based guideline includes research to support more effective identification and management of patients with hoarseness (dysphonia). The primary purpose of the guideline is to improve the quality of care for patients with hoarseness (dysphonia) based on current best evidence.

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