Current trends in the structure—activity relationship studies of the endogenous agouti-related protein (AGRP) melanocortin receptor antagonist

Melanocortin Receptor ◽

Activity Relationship ◽

Related Protein ◽

Current Trends ◽

Structure Activity ◽

Agouti Related Protein

Current Trends in the Structure—Activity Relationship Studies of the Endogenous Agouti-Related Protein (AGRP) Melanocortin Receptor Antagonist

ChemInform ◽

10.1002/chin.200550247 ◽

2005 ◽

Vol 36 (50) ◽

Author(s):

Andrzej M. Wilczynski ◽

Christine G. Joseph ◽

Carrie Haskell-Luevano

Keyword(s):

Receptor Antagonist ◽

Melanocortin Receptor ◽

Activity Relationship ◽

Related Protein ◽

Current Trends ◽

Structure Activity ◽

Agouti Related Protein

Structure–Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b00856 ◽

2017 ◽

Vol 60 (19) ◽

pp. 8103-8114 ◽

Cited By ~ 6

Author(s):

Mark D. Ericson ◽

Katie T. Freeman ◽

Sathya M. Schnell ◽

Katlyn A. Fleming ◽

Carrie Haskell-Luevano

Keyword(s):

Receptor Antagonist ◽

Inverse Agonist ◽

Activity Relationship ◽

Related Protein ◽

Signaling Protein ◽

Structure Activity ◽

Melanocortin 4 Receptor ◽

Agouti Related Protein

Current trends in quantitative structure–activity relationship validation and applications on drug discovery

Future Science OA ◽

10.4155/fsoa-2017-0052 ◽

2017 ◽

Vol 3 (4) ◽

pp. FSO214 ◽

Cited By ~ 2

Author(s):

Vinicius G Maltarollo ◽

Thales Kronenberger ◽

Carsten Wrenger ◽

Kathia M Honorio

Keyword(s):

Drug Discovery ◽

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Current Trends ◽

Structure Activity

Structure-activity relationship of nantenine, a novel 5-HT2A receptor antagonist and its analysis by molecular modeling

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)47568-9 ◽

2000 ◽

Vol 82 ◽

pp. 22

Author(s):

Yasushi Ohizumi-Indra ◽

Kimihiro Matsunaga ◽

Osamu Hoshino ◽

Masaji Ishiguro

Keyword(s):

Molecular Modeling ◽

Receptor Antagonist ◽

Activity Relationship ◽

Its Analysis ◽

Structure Activity ◽

Structure−Activity Relationship Studies Leading to the Identification of (2E)-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a Potent and Selective Prostanoid EP3 Receptor Antagonist, as a Novel Antiplatelet Agent That Does Not Prolong Bleeding

Journal of Medicinal Chemistry ◽

10.1021/jm9005912 ◽

2010 ◽

Vol 53 (1) ◽

pp. 18-36 ◽

Cited By ~ 31

Author(s):

Jasbir Singh ◽

Wayne Zeller ◽

Nian Zhou ◽

Georgeta Hategan ◽

Rama K. Mishra ◽

...

Keyword(s):

Receptor Antagonist ◽

Antiplatelet Agent ◽

Activity Relationship ◽

Structure Activity ◽

Ep3 Receptor

Structure–activity relationship and signal transduction of γ-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor

Peptides ◽

10.1016/s0196-9781(02)00040-2 ◽

2002 ◽

Vol 23 (6) ◽

pp. 1077-1086 ◽

Cited By ~ 8

Author(s):

Lies Langouche ◽

Katrien Pals ◽

Carl Denef

Keyword(s):

Signal Transduction ◽

Melanocortin Receptor ◽

Activity Relationship ◽

Gh3 Cells ◽

Structure Activity

Structure–activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.06.095 ◽

2008 ◽

Vol 18 (15) ◽

pp. 4287-4290 ◽

Cited By ~ 12

Author(s):

Kaori Cho ◽

Fumito Uneuchi ◽

Yuko Kato-Nakamura ◽

Jun-ichi Namekawa ◽

Seiichi Ishizuka ◽

...

Keyword(s):

Vitamin D ◽

Receptor Antagonist ◽

Vitamin D Receptor ◽

Activity Relationship ◽

Structure Activity

Structure-activity relationship of [Nphe1 ]-NC-(1-13)-NH2 , a pure and selective nociceptin/orphanin FQ receptor antagonist

Journal of Peptide Research ◽

10.1111/j.1399-3011.2001.00820.x ◽

2001 ◽

Vol 57 (3) ◽

pp. 215-222 ◽

Cited By ~ 2

Author(s):

R. Guerrini ◽

S. Salvadori ◽

G. Calo' ◽

R. Bigoni ◽

D. Rizzi ◽

...

Keyword(s):

Receptor Antagonist ◽

Activity Relationship ◽

Orphanin Fq ◽

Structure Activity ◽

Structure−Activity Relationship of (1-Aryl-2-piperazinylethyl)piperazines: Antagonists for the AGRP/Melanocortin Receptor Binding

Journal of Medicinal Chemistry ◽

10.1021/jm0255522 ◽

2003 ◽

Vol 46 (1) ◽

pp. 9-11 ◽

Cited By ~ 27

Author(s):

Premilla N. Arasasingham ◽

Christopher Fotsch ◽

Xiaohu Ouyang ◽

Mark H. Norman ◽

Michael G. Kelly ◽

...

Keyword(s):

Receptor Binding ◽

Melanocortin Receptor ◽

Activity Relationship ◽

Structure Activity ◽

Structure–activity relationship of [Nphe1]-NC-(1-13)-NH2, a pure and selective nociceptin/orphanin FQ receptor antagonist

Journal of Peptide Research ◽

10.1034/j.1399-3011.2001.057003215.x ◽

2001 ◽

Vol 57 (3) ◽

pp. 215-222

Author(s):

R. Guerrini ◽

S. Salvadori ◽

G. Calo' ◽

R. Bigoni ◽

D. Rizzi ◽

...

Keyword(s):

Receptor Antagonist ◽

Activity Relationship ◽

Orphanin Fq ◽

Structure Activity ◽