scholarly journals Ultra‐high dose rate electron beams and the FLASH effect: from preclinical evidence to a new radiotherapy paradigm

2022 ◽  
Author(s):  
Emil Schüler ◽  
Munjal Acharya ◽  
Pierre Montay‐Gruel ◽  
Billy W. Loo ◽  
Marie‐Catherine Vozenin ◽  
...  
Keyword(s):  
Dose Rate ◽  
Electron Beams ◽  
High Dose Rate ◽  
High Dose

scholarly journals The challenge of ionisation chamber dosimetry in ultra-short pulsed high dose-rate Very High Energy Electron beams

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
M. McManus ◽  
F. Romano ◽  
N. D. Lee ◽  
W. Farabolini ◽  
A. Gilardi ◽  
...  
Keyword(s):  
Dose Rate ◽  
Electron Beams ◽  
High Energy ◽  
High Dose Rate ◽  
Energy Electron ◽  
High Dose ◽  
High Energy Electron ◽  
Ionisation Chamber ◽  
Very High Energy ◽  
Very High

Radiobiological characterization of the very high dose rate and dose per pulse electron beams produced by an IORT (intra operative radiation therapy) dedicated linac

2017 ◽  
Vol 6 (S5) ◽  
pp. S761-S768 ◽  
Author(s):  
Paola Scampoli ◽  
Carmela Carpentieri ◽  
Marco Giannelli ◽  
Vera Magaddino ◽  
Lorenzo Manti ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Dose Rate ◽  
Electron Beams ◽  
High Dose Rate ◽  
High Dose ◽  
Pulse Electron ◽  
Very High

scholarly journals Calorimeter for Real-Time Dosimetry of Pulsed Ultra-High Dose Rate Electron Beams

2020 ◽  
Vol 8 ◽  
Author(s):  
Alexandra Bourgouin ◽  
Andreas Schüller ◽  
Thomas Hackel ◽  
Rafael Kranzer ◽  
Daniela Poppinga ◽  
...  
Keyword(s):  
Dose Rate ◽  
Real Time ◽  
Electron Beams ◽  
High Dose Rate ◽  
High Dose

scholarly journals General ion recombination effect in a liquid ionization chamber in high-dose-rate pulsed photon and electron beams

2018 ◽  
Vol 59 (3) ◽  
pp. 282-285 ◽  
Author(s):  
Hideyuki Takei ◽  
Tomonori Isobe ◽  
Nozomi Kitamura ◽  
Yutaro Mori ◽  
Tetsuya Tomita ◽  
...  
Keyword(s):  
Dose Rate ◽  
Ionization Chamber ◽  
Electron Beams ◽  
High Dose Rate ◽  
High Dose ◽  
Liquid Ionization Chamber ◽  
Ion Recombination ◽  
Recombination Effect ◽  
Liquid Ionization

scholarly journals Optical Filter-Embedded Fiber-Optic Radiation Sensor for Ultra-High Dose Rate Electron Beam Dosimetry

Sensors ◽  
2021 ◽  
Vol 21 (17) ◽  
pp. 5840
Author(s):  
Dong-Hyeok Jeong ◽  
Manwoo Lee ◽  
Heuijin Lim ◽  
Sang-Koo Kang ◽  
Kyohyun Lee ◽  
...  
Keyword(s):  
Optical Fiber ◽  
Dose Rate ◽  
Fiber Optic ◽  
Electron Beams ◽  
Optical Filter ◽  
High Dose Rate ◽  
High Dose ◽  
Optic Radiation ◽  
Normal Tissues ◽  
Radiation Sensor

FLASH radiotherapy is an emerging radiotherapy technique used to spare normal tissues. It employs ultra-high dose rate radiation beams over 40 Gy/s, which is significantly higher than those of conventional radiotherapy. In this study, a fiber-optic radiation sensor (FORS) was fabricated using a plastic scintillator, an optical filter, and a plastic optical fiber to measure the ultra-high dose rate electron beams over 40 Gy/s used in FLASH radiotherapy. The radiation-induced emissions, such as Cherenkov radiation and fluorescence generated in a transmitting optical fiber, were spectrally discriminated from the light outputs of the FORS. To evaluate the linearity and dose rate dependence of the FORS, the outputs of the fiber-optic radiation sensor were measured according to distances from an electron scattering device, and the results were compared with those of an ionization chamber and radiochromic films. Finally, the percentage depth doses were obtained using the FORS as a function of depth in a water phantom. This study found that ultra-high dose rate electron beams over 40 Gy/s could be measured in real time using a FORS.

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