scholarly journals Absolute cerebral blood flow quantification with pulsed arterial spin labeling during hyperoxia corrected with the simultaneous measurement of the longitudinal relaxation time of arterial blood

2011 ◽  
Vol 67 (6) ◽  
pp. 1556-1565 ◽  
Author(s):  
David T. Pilkinton ◽  
Teruyuki Hiraki ◽  
John A. Detre ◽  
Joel H. Greenberg ◽  
Ravinder Reddy
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Relaxation Time ◽  
Simultaneous Measurement ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Flow Quantification ◽  
Longitudinal Relaxation Time ◽  
Blood Flow Quantification ◽  
Arterial Blood

scholarly journals Effects of arterial transit delay on cerebral blood flow quantification using arterial spin labeling in an elderly cohort

2016 ◽  
Vol 45 (2) ◽  
pp. 472-481 ◽  
Author(s):  
Weiying Dai ◽  
Tamara Fong ◽  
Richard N. Jones ◽  
Edward Marcantonio ◽  
Eva Schmitt ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Flow Quantification ◽  
Blood Flow Quantification ◽  
Elderly Cohort ◽  
Transit Delay

scholarly journals In Vivo T1 of Blood Measurements in Children with Sickle Cell Disease Improve Cerebral Blood Flow Quantification from Arterial Spin-Labeling MRI

2016 ◽  
Vol 37 (9) ◽  
pp. 1727-1732 ◽  
Author(s):  
L. Václavů ◽  
V. van der Land ◽  
D.F.R. Heijtel ◽  
M.J.P. van Osch ◽  
M.H. Cnossen ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Flow Quantification ◽  
Cell Disease ◽  
Blood Flow Quantification

scholarly journals Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

2012 ◽  
Vol 2 (1) ◽  
pp. 47 ◽  
Author(s):  
Agnieszka Boś ◽  
Ralf Bergmann ◽  
Klaus Strobel ◽  
Frank Hofheinz ◽  
Jörg Steinbach ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Flow Quantification ◽  
Blood Flow Quantification ◽  
Radioactive Microsphere

scholarly journals Cerebral blood flow quantification in swine using pseudo-continuous arterial spin labeling

2013 ◽  
Vol 38 (5) ◽  
pp. 1111-1118 ◽  
Author(s):  
Megan E. Johnston ◽  
Zhenlin Zheng ◽  
Joseph A. Maldjian ◽  
Christopher T. Whitlow ◽  
Michael J. Morykwas ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Flow Quantification ◽  
Blood Flow Quantification ◽  
Continuous Arterial Spin Labeling

scholarly journals Comparison of cerebral blood flow measurement with [15O]-water positron emission tomography and arterial spin labeling magnetic resonance imaging: A systematic review

2016 ◽  
Vol 36 (5) ◽  
pp. 842-861 ◽  
Author(s):  
Audrey P Fan ◽  
Hesamoddin Jahanian ◽  
Samantha J Holdsworth ◽  
Greg Zaharchuk
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Emission Tomography ◽  
Flow Measurements ◽  
Arterial Blood ◽  
Positron Emission

Noninvasive imaging of cerebral blood flow provides critical information to understand normal brain physiology as well as to identify and manage patients with neurological disorders. To date, the reference standard for cerebral blood flow measurements is considered to be positron emission tomography using injection of the [15O]-water radiotracer. Although [15O]-water has been used to study brain perfusion under normal and pathological conditions, it is not widely used in clinical settings due to the need for an on-site cyclotron, the invasive nature of arterial blood sampling, and experimental complexity. As an alternative, arterial spin labeling is a promising magnetic resonance imaging technique that magnetically labels arterial blood as it flows into the brain to map cerebral blood flow. As arterial spin labeling becomes more widely adopted in research and clinical settings, efforts have sought to standardize the method and validate its cerebral blood flow values against positron emission tomography-based cerebral blood flow measurements. The purpose of this work is to critically review studies that performed both [15O]-water positron emission tomography and arterial spin labeling to measure brain perfusion, with the aim of better understanding the accuracy and reproducibility of arterial spin labeling relative to the positron emission tomography reference standard.

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